Linking energy sensing to suppression of JAK-STAT signalling: A potential route for repurposing AMPK activators?
(2017)
Journal Article
Speirs, C., Williams, J. J. L., Riches, K., Salt, I. P., & Palmer, T. M. (2018). Linking energy sensing to suppression of JAK-STAT signalling: A potential route for repurposing AMPK activators?. Pharmacological research : the official journal of the Italian Pharmacological Society, 128, 88-100. https://doi.org/10.1016/j.phrs.2017.10.001
Exaggerated Janus kinase-signal transducer and activator of transcription (JAK-STAT) signalling is key to the pathogenesis of pro-inflammatory disorders, such as rheumatoid arthritis and cardiovascular diseases. Mutational activation of JAKs is also... Read More about Linking energy sensing to suppression of JAK-STAT signalling: A potential route for repurposing AMPK activators?.