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Professor Ian Chetter's Outputs (176)

Extreme low-lying carotid bifurcations (2016)
Journal Article
Harwood, A. E., Leung, C. C. M., Smith, G. E., & Chetter, I. C. (2016). Extreme low-lying carotid bifurcations. Vascular Medicine, 21(4), 394-395. https://doi.org/10.1177/1358863X15627208

A 52-year-old male with no past medical history was referred to the transient ischaemic attack (TIA) clinic following an event at home. The transient symptoms were of an inability to move his left arm and leg for a period of approximately 15 minutes.... Read More about Extreme low-lying carotid bifurcations.

The Impact of Vein Mechanical Compliance on Arteriovenous Fistula Outcomes (2016)
Journal Article
Smith, G. E., Barnes, R., Chetter, I. C., Barnes, R., & Fagan, M. (2016). The Impact of Vein Mechanical Compliance on Arteriovenous Fistula Outcomes. Annals of vascular surgery, 32, 9-14. https://doi.org/10.1016/j.avsg.2015.11.002

© 2016 Elsevier Inc. Background Arteriovenous fistulae (AVFs) are the preferred access for hemodialysis but suffer a high early failure rate. The aim of this study was to determine how venous distensibility, as measured in vitro, relates to early out... Read More about The Impact of Vein Mechanical Compliance on Arteriovenous Fistula Outcomes.

Infection in prosthetic material (2015)
Journal Article
Smith, G., & Chetter, I. (2015). Infection in prosthetic material. Surgery (Oxford), 33(11), 559-564. https://doi.org/10.1016/j.mpsur.2015.08.003

Surgical site infection (SSI) occurs when a wound created as part of a surgical procedure becomes infected. SSI is one of the most common healthcare-associated infections and occurs in approximately 5% of patients undergoing a surgical procedure. SSI... Read More about Infection in prosthetic material.

A prospective observational study to assess the impact of operator seniority on outcome following arteriovenous fistula formation (2015)
Journal Article
Barnes, R., Smith, G. E., & Chetter, I. C. (2015). A prospective observational study to assess the impact of operator seniority on outcome following arteriovenous fistula formation. The journal of vascular access, 16(5), 372-376. https://doi.org/10.5301/jva.5000401

Purpose: Arteriovenous fistula (AVF) surgery affords an excellent opportunity for junior surgeons to learn key vascular techniques. However, implementation of the European Working Time Directive has reduced trainee surgeon’s working hours, leading to... Read More about A prospective observational study to assess the impact of operator seniority on outcome following arteriovenous fistula formation.

A review of the potential local mechanisms by which exercise improves functional outcomes in intermittent claudication (2015)
Journal Article
Harwood, A., Cayton, T., Sarvanandan, R., Lane, R., & Chetter, I. (2016). A review of the potential local mechanisms by which exercise improves functional outcomes in intermittent claudication. Annals of vascular surgery, 30, 312-320. https://doi.org/10.1016/j.avsg.2015.05.043

© 2016 Elsevier Inc. All rights reserved. Background Intermittent claudication (IC) is a common condition which is associated with significant quality of life limitation. National Institute for Health and Care Excellence guidelines recommend a group-... Read More about A review of the potential local mechanisms by which exercise improves functional outcomes in intermittent claudication.

A systematic review and meta-analysis of systemic intraoperative anticoagulation during arteriovenous access formation for dialysis (2015)
Journal Article
Smith, G. E., Souroullos, P., Cayton, T., Harwood, A., Carradice, D., & Chetter, I. C. (2016). A systematic review and meta-analysis of systemic intraoperative anticoagulation during arteriovenous access formation for dialysis. The journal of vascular access, 17(1), 1-5. https://doi.org/10.5301/jva.5000484

Purpose: Surgical arteriovenous fistula (AVF) or graft (AVG) is preferred to a central venous catheter for dialysis access. Surgical access may suffer thrombosis early after placement and systemic anticoagulation during surgical access formation may... Read More about A systematic review and meta-analysis of systemic intraoperative anticoagulation during arteriovenous access formation for dialysis.

Individual-patient meta-analysis of three randomized trials comparing endovascular versus open repair for ruptured abdominal aortic aneurysm (2015)
Journal Article
Chetter, I., Sweeting, M., Balm, R., Desgranges, P., Ulug, P., Powell, J., & Ruptured Aneurysm Trialists. (2015). Individual-patient meta-analysis of three randomized trials comparing endovascular versus open repair for ruptured abdominal aortic aneurysm. British journal of surgery, 102(10), 1229-1239. https://doi.org/10.1002/bjs.9852

BackgroundThe benefits of endovascular repair of ruptured abdominal aortic aneurysm remain controversial, without any strong evidence about advantages in specific subgroups.MethodsAn individual-patient data meta-analysis of three recent randomized tr... Read More about Individual-patient meta-analysis of three randomized trials comparing endovascular versus open repair for ruptured abdominal aortic aneurysm.

The ETTAA study protocol: A UK-wide observational study of 'Effective treatments for thoracic aortic aneurysm' (2015)
Journal Article
Sastry, P., Hughes, V., Hayes, P., Vallabhaneni, S. R., Sharples, L., Thompson, M., Catarino, P., Moorjani, N., Vale, L., Gray, J., Cook, A., Elefteriades, J., Large, S. R., & on behalf of the ETTAA collaborators. (2015). The ETTAA study protocol: A UK-wide observational study of 'Effective treatments for thoracic aortic aneurysm'. BMJ open, 5(6), e008147-e008147. https://doi.org/10.1136/bmjopen-2015-008147

© 2015 BMJ Open. Introduction: Chronic thoracic aortic aneurysm (CTAA) affecting the arch or descending aorta is an indolent but life-threatening condition with a rising prevalence as the UK population ages. Treatment may be in the form of open surgi... Read More about The ETTAA study protocol: A UK-wide observational study of 'Effective treatments for thoracic aortic aneurysm'.

Endovascular strategy or open repair for ruptured abdominal aortic aneurysm: One-year outcomes from the IMPROVE randomized trial (2015)
Journal Article
Braithwaite, B., Greenhalgh, R. M., Grieve, R., Hassan, T. B., Moore, F., Nicholson, A. A., Soong, C. V., Heatley, F., Anjum, A., Kalinowska, G., Gomes, M., Powell, J. T., Hinchliffe, R., Sweeting, M., Thompson, M. M., Thompson, S. G., Ulug, P., Roberts, I., Bell, P. R., Cheetham, A., …Wilson, L. (2015). Endovascular strategy or open repair for ruptured abdominal aortic aneurysm: One-year outcomes from the IMPROVE randomized trial. European Heart Journal, 36(31), 2061-2069. https://doi.org/10.1093/eurheartj/ehv125

© 2015 The Author. Aims To report the longer term outcomes following either a strategy of endovascular repair first or open repair of ruptured abdominal aortic aneurysm, which are necessary for both patient and clinical decision-making. Methods and r... Read More about Endovascular strategy or open repair for ruptured abdominal aortic aneurysm: One-year outcomes from the IMPROVE randomized trial.

Systematic review of compression following treatment for varicose veins (2015)
Journal Article
El-Sheikha, J., Carradice, D., Nandhra, S., Leung, C., Smith, G., Campbell, B., & Chetter, I. (2015). Systematic review of compression following treatment for varicose veins. British journal of surgery, 102(7), 719-725. https://doi.org/10.1002/bjs.9788

Background Consensus regarding compression following treatment of varicose veins has yet to be reached. This systematic review aims to establish the optimal compression regimen after venous treatment. Methods A systematic review of MEDLINE, Embase an... Read More about Systematic review of compression following treatment for varicose veins.

Clinical and cost-effectiveness of foam sclerotherapy, endovenous laser ablation and surgery for varicose veins: results from the CLASS trial (2015)
Journal Article
Brittenden, J., Cotton, S. C., Elders, A., Tassie, E., Scotland, G., Ramsay, C. R., Norrie, J., Burr, J., Francis, J., Wileman, S., Campbell, B., Bachoo, P., Chetter, I., Gough, M., Earnshaw, J., Lees, T., Scott, J., Baker, S. A., MacLennan, G., Prior, M., …Campbell, M. K. (2015). Clinical and cost-effectiveness of foam sclerotherapy, endovenous laser ablation and surgery for varicose veins: results from the CLASS trial. Health Technology Assessment, 19(27), 1-342. https://doi.org/10.3310/hta19270

Background
Foam sclerotherapy (foam) and endovenous laser ablation (EVLA) have emerged as alternative treatments to surgery for patients with varicose veins, but uncertainty exists regarding their effectiveness in the medium to longer term.

Objec... Read More about Clinical and cost-effectiveness of foam sclerotherapy, endovenous laser ablation and surgery for varicose veins: results from the CLASS trial.

A randomized clinical trial of endovenous laser ablation versus conventional surgery for small saphenous varicose veins (2015)
Journal Article
Nandhra, S., El-sheikha, J., Carradice, D., Wallace, T., Souroullas, P., Samuel, N., Smith, G., & Chetter, I. C. (2015). A randomized clinical trial of endovenous laser ablation versus conventional surgery for small saphenous varicose veins. Journal of vascular surgery, 61(3), 741-746. https://doi.org/10.1016/j.jvs.2014.09.037

Background: This randomized clinical trial compared endovenous laser ablation (EVLA) and surgical ligation with attempted stripping in the treatment of small saphenous vein (SSV) insufficiency. The early results demonstrated that EVLA was more likely... Read More about A randomized clinical trial of endovenous laser ablation versus conventional surgery for small saphenous varicose veins.

The effect of aortic morphology on peri-operative mortality of ruptured abdominal aortic aneurysm (2015)
Journal Article
IMPROVE Trial Investigators. (2015). The effect of aortic morphology on peri-operative mortality of ruptured abdominal aortic aneurysm. European Heart Journal, 36(21), 1328-1334. https://doi.org/10.1093/eurheartj/ehu521

Aims To investigate whether aneurysm shape and extent, which indicate whether a patient with ruptured abdominal aortic aneurysm (rAAA) is eligible for endovascular repair (EVAR), influence the outcome of both EVAR and open surgical repair. Methods an... Read More about The effect of aortic morphology on peri-operative mortality of ruptured abdominal aortic aneurysm.

Compression regimes after endovenous ablation for superficial venous insufficiency – A survey of members of the Vascular Society of Great Britain and Ireland (2015)
Journal Article
El-Sheikha, J., Nandhra, S., Carradice, D., Acey, C., Smith, G., Campbell, B., & Chetter, I. (2016). Compression regimes after endovenous ablation for superficial venous insufficiency – A survey of members of the Vascular Society of Great Britain and Ireland. Phlebology, 31(1), 16-22. https://doi.org/10.1177/0268355514567732

Introduction: The optimal compression regime following ultrasound guided foam sclerotherapy (UGFS), radiofrequency ablation (RFA) and endovenous laser ablation (EVLA) for varicose veins is not known. The aim of this study was to document current prac... Read More about Compression regimes after endovenous ablation for superficial venous insufficiency – A survey of members of the Vascular Society of Great Britain and Ireland.

The FINISH-3 trial: A phase 3, international, randomized, single-blind, controlled trial of topical fibrocaps in intraoperative surgical hemostasis (2014)
Journal Article
Bochicchio, G. V., Gupta, N., Porte, R. J., Renkens, K. L., Pattyn, P., Topal, B., Troisi, R. I., Muir, W., Chetter, I., Gillen, D. L., Zuckerman, L. A., & Frohna, P. A. (2015). The FINISH-3 trial: A phase 3, international, randomized, single-blind, controlled trial of topical fibrocaps in intraoperative surgical hemostasis. Journal of The American College of Surgeons, 220(1), 70-81. https://doi.org/10.1016/j.jamcollsurg.2014.09.019

Background This Phase 3, international, randomized, single-blind, controlled trial (FINISH-3) compared the efficacy and safety of Fibrocaps, a ready-to-use, dry-powder fibrin sealant containing human plasma-derived thrombin and fibrinogen, vs gelatin... Read More about The FINISH-3 trial: A phase 3, international, randomized, single-blind, controlled trial of topical fibrocaps in intraoperative surgical hemostasis.

Cost-effectiveness of ultrasound-guided foam sclerotherapy, endovenous laser ablation or surgery as treatment for primary varicose veins from the randomized CLASS trial: Cost-effectiveness of primary varicose vein treatments (2014)
Journal Article
Tassie, E., Scotland, G., Brittenden, J., Cotton, S. C., Elders, A., Campbell, M. K., Campbell, B., Gough, M., Burr, J. M., Ramsay, C. R., & on behalf of the CLASS study team. (2014). Cost-effectiveness of ultrasound-guided foam sclerotherapy, endovenous laser ablation or surgery as treatment for primary varicose veins from the randomized CLASS trial: Cost-effectiveness of primary varicose vein treatments. British journal of surgery, 101(12), 1532-1540. https://doi.org/10.1002/bjs.9595

© 2014 Crown copyright. Background: The treatment of patients with varicose veins constitutes a considerable workload and financial burden to the National Health Service. This study aimed to assess the cost-effectiveness of ultrasound-guided foam scl... Read More about Cost-effectiveness of ultrasound-guided foam sclerotherapy, endovenous laser ablation or surgery as treatment for primary varicose veins from the randomized CLASS trial: Cost-effectiveness of primary varicose vein treatments.

A randomized trial comparing treatments for varicose veins. (2014)
Journal Article
Brittenden, J., Cotton, S. C., Elders, A., Ramsay, C. R., Norrie, J., Burr, J., Campbell, B., Bachoo, P., Chetter, I., Gough, M., Earnshaw, J., Lees, T., Scott, J., Baker, S. A., Francis, J., Tassie, E., Scotland, G., Wileman, S., & Campbell, M. K. (2014). A randomized trial comparing treatments for varicose veins. New England Journal of Medicine, 371, 1218-1227. https://doi.org/10.1056/NEJMoa1400781

BACKGROUND
Ultrasound-guided foam sclerotherapy and endovenous laser ablation are widely used alternatives to surgery for the treatment of varicose veins, but their comparative effectiveness and safety remain uncertain.

METHODS
In a randomized t... Read More about A randomized trial comparing treatments for varicose veins..

A comparison of the effectiveness of treating those with and without the complications of superficial venous insufficiency (2014)
Journal Article
Carradice, D., Wallace, T., Gohil, R., & Chetter, I. (2014). A comparison of the effectiveness of treating those with and without the complications of superficial venous insufficiency. Annals of Surgery, 260(2), 396-401. https://doi.org/10.1097/sla.0000000000000541

Objective: To test the hypothesis that patients with soft tissue changes related to superficial venous insufficiency (SVI) have greater benefits from treatment than those with only symptomatic varicose veins.
Background: A commonly held view is that... Read More about A comparison of the effectiveness of treating those with and without the complications of superficial venous insufficiency.