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Professor Sean Carroll

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Sean Carroll

Professor of Sport, Health and Exercise Science


The Rating of Perceived Exertion at the Ventilatory Anaerobic Threshold in Patients with Coronary Heart Disease - Prescribing Implications for Exercise-Based Cardiovascular Rehabilitation: A CARE CR study (2021)
Journal Article
Nichols, S., Engin, B., Carroll, S., Buckley, J., & Ingle, L. (2021). The Rating of Perceived Exertion at the Ventilatory Anaerobic Threshold in Patients with Coronary Heart Disease - Prescribing Implications for Exercise-Based Cardiovascular Rehabilitation: A CARE CR study. Annals of physical and rehabilitation medicine, 64(6), Article 101462. https://doi.org/10.1016/j.rehab.2020.101462

Background: Exercise prescription guidelines for patients undertaking cardiovascular rehabilitation (CR) are based on heart rate training zones and ratings of perceived exertion (RPE). In the UK, guidelines indicate that patients should exercise at a... Read More about The Rating of Perceived Exertion at the Ventilatory Anaerobic Threshold in Patients with Coronary Heart Disease - Prescribing Implications for Exercise-Based Cardiovascular Rehabilitation: A CARE CR study.

Ratings of perceived exertion at the ventilatory anaerobic threshold in people with coronary heart disease: A CARE CR study (2021)
Journal Article
Nichols, S., Engin, B., Carroll, S., Buckley, J., & Ingle, L. (2021). Ratings of perceived exertion at the ventilatory anaerobic threshold in people with coronary heart disease: A CARE CR study. Annals of physical and rehabilitation medicine, 64(6), Article 101462. https://doi.org/10.1016/j.rehab.2020.101462

Background: Exercise prescription guidelines for individuals undergoing cardiovascular rehabilitation (CR) are often based on heart rate training zones and rating of perceived exertion (RPE). United Kingdom guidelines indicate that patients should ex... Read More about Ratings of perceived exertion at the ventilatory anaerobic threshold in people with coronary heart disease: A CARE CR study.

Love is in the hair: arginine methylation of human hair proteins as novel cardiovascular biomarkers (2021)
Journal Article
Marsden, A. J., Riley, D. R., Birkett, S., Rodriguez-Barucg, Q., Guinn, B. A., Carroll, S., …Beltran-Alvarez, P. (in press). Love is in the hair: arginine methylation of human hair proteins as novel cardiovascular biomarkers. Amino acids, https://doi.org/10.1007/s00726-021-03024-5

Cardiovascular disease is the major cause of death worldwide. Extensive cardiovascular biomarkers are available using blood tests but very few, if any, investigations have described non-invasive tests for cardiovascular biomarkers based on readily av... Read More about Love is in the hair: arginine methylation of human hair proteins as novel cardiovascular biomarkers.

The effects of exercise to promote quality of life in individuals with traumatic brain injuries: a systematic review (2020)
Journal Article
O'Caroll, G., King, S. L., Carroll, S., Perry, J., & Vanicek, N. (in press). The effects of exercise to promote quality of life in individuals with traumatic brain injuries: a systematic review. Brain Injury, 1-13. https://doi.org/10.1080/02699052.2020.1812117

© 2020 Taylor & Francis Group, LLC. Objective: To systematically review the effects of exercise interventions that may enhance quality of life (QOL) in individuals with traumatic brain injury (TBI). Methods: A systematic search was conducted using... Read More about The effects of exercise to promote quality of life in individuals with traumatic brain injuries: a systematic review.

Considering the feasibility, tolerability and safety of high intensity interval training as a novel treatment for patients with intermittent claudication (2020)
Journal Article
Pymer, S., Ibeggazene, S., Palmer, J., Smith, G. E., Carroll, S., Ingle, L., …Chetter, I. C. (2021). Considering the feasibility, tolerability and safety of high intensity interval training as a novel treatment for patients with intermittent claudication. Journal of Cardiopulmonary Rehabilitation and Prevention, 41(3), 188-193. https://doi.org/10.1097/HCR.0000000000000551

Considering the Feasibility, Tolerability and Safety of High-Intensity Interval Training as a Novel Treatment for Patients with Intermittent Claudication. Structured Abstract Purpose: This study assessed the feasibility, tolerability, safety and... Read More about Considering the feasibility, tolerability and safety of high intensity interval training as a novel treatment for patients with intermittent claudication.

Characterising the application of the “progressive overload” principle of exercise training within cardiac rehabilitation: a United Kingdom-based community programme (2020)
Journal Article
Khushhal, A., Nichols, S., Carroll, S., Abt, G., & Ingle, L. (in press). Characterising the application of the “progressive overload” principle of exercise training within cardiac rehabilitation: a United Kingdom-based community programme. PLoS ONE, 15(8), Article e0237197. https://doi.org/10.1371/journal.pone.0237197

BACKGROUND: Recent concerns have cast doubt over the effectiveness of cardiac rehabilitation [CR] programmes for improving cardiorespiratory fitness [CRF] in patients with a history of cardiac disease in the United Kingdom [UK]. We aimed to character... Read More about Characterising the application of the “progressive overload” principle of exercise training within cardiac rehabilitation: a United Kingdom-based community programme.

high INtensity Interval Training In pATiEnts with intermittent claudication (INITIATE): protocol for a multi-centre, proof-of-concept, prospective interventional study (2020)
Journal Article
Pymer, S., Harwood, A., Ibeggazene, S., McGregor, G., Huang, C., Twiddy, M., …Chetter, I. C. (2020). high INtensity Interval Training In pATiEnts with intermittent claudication (INITIATE): protocol for a multi-centre, proof-of-concept, prospective interventional study. BMJ open, 10(7), Article e038825. https://doi.org/10.1136/bmjopen-2020-038825

Introduction: The first-line recommended treatment for patients with intermittent claudication (IC), is a supervised exercise programme (SEP), which includes a minimum of 2 hours exercise per week over a 12-week period. However, provision, uptake, an... Read More about high INtensity Interval Training In pATiEnts with intermittent claudication (INITIATE): protocol for a multi-centre, proof-of-concept, prospective interventional study.

Routine exercise-based cardiac rehabilitation does not increase aerobic fitness: A CARE CR study (2020)
Journal Article
Nichols, S., Taylor, C., Goodman, T., Page, R., Kallvikbacka-Bennett, A., Nation, F., …Ingle, L. (2020). Routine exercise-based cardiac rehabilitation does not increase aerobic fitness: A CARE CR study. International journal of cardiology, 305, 25-34. https://doi.org/10.1016/j.ijcard.2020.01.044

© 2020 The Authors Background: Recent evidence suggests that routine exercise-based cardiac rehabilitation (CR) may not lead to a substantial increase in estimated peak oxygen uptake (V̇O2peak). This could reduce the potential benefits of CR and expl... Read More about Routine exercise-based cardiac rehabilitation does not increase aerobic fitness: A CARE CR study.

The effect of atorvastatin (and subsequent metformin) on adipose tissue acylation-stimulatory-protein concentration and inflammatory biomarkers in overweight/obese women with polycystic ovary syndrome (2019)
Journal Article
Sathyapalan, T., Hobkirk, J. P., Javed, Z., Carroll, S., Coady, A. M., Pemberton, P., …Atkin, S. L. (2019). The effect of atorvastatin (and subsequent metformin) on adipose tissue acylation-stimulatory-protein concentration and inflammatory biomarkers in overweight/obese women with polycystic ovary syndrome. Frontiers in endocrinology, 10(JUN), Article 394. https://doi.org/10.3389/fendo.2019.00394

Copyright © 2019 Sathyapalan, Hobkirk, Javed, Carroll, Coady, Pemberton, Smith, Cianflone and Atkin. Background: Atorvastatin has been shown to improve cardiovascular risk (CVR) indices in women with polycystic ovary syndrome (PCOS). Low-grade chroni... Read More about The effect of atorvastatin (and subsequent metformin) on adipose tissue acylation-stimulatory-protein concentration and inflammatory biomarkers in overweight/obese women with polycystic ovary syndrome.

Insufficient exercise intensity for clinical benefit? Monitoring and quantification of a community-based Phase III cardiac rehabilitation programme: A United Kingdom perspective (2019)
Journal Article
Khushhal, A., Nichols, S., Carroll, S., Abt, G., & Ingle, L. (in press). Insufficient exercise intensity for clinical benefit? Monitoring and quantification of a community-based Phase III cardiac rehabilitation programme: A United Kingdom perspective. PLoS ONE, 14(6), Article e0217654. https://doi.org/10.1371/journal.pone.0217654

Abstract: Background: In recent years, criticism of the percentage range approach for individualised exercise prescription has intensified and we were concerned that sub-optimal exercise dose (especially intensity) may be in part responsible for the... Read More about Insufficient exercise intensity for clinical benefit? Monitoring and quantification of a community-based Phase III cardiac rehabilitation programme: A United Kingdom perspective.