Dr Leonid Nikitenko's Outputs (3)

Endothelial cells and cancer (2006)
Book Chapter
Nikitenko, L., & Boshoff, C. (2006). Endothelial cells and cancer. In S. Moncada, & A. Higgs (Eds.), The Vascular Endothelium II (307-334). Springer Verlag. https://doi.org/10.1007/3-540-36028-X_10

Endothelial cells play a key role in the development and function of blood and lymph vessels. Excessive proliferation and transformation of endothelial cells lead to pathological angiogenesis/ lymphangiogenesis or vascular malfunctions which are hall... Read More about Endothelial cells and cancer.

Expression of terminally glycosylated calcitonin receptor - Like receptor in uterine leiomyoma: Endothelial phenotype and association with microvascular density (2006)
Journal Article
Nikitenko, L. L., Cross, T., Campo, L., Turley, H., Leek, R., Manek, S., Bicknell, R., & Rees, M. C. (2006). Expression of terminally glycosylated calcitonin receptor - Like receptor in uterine leiomyoma: Endothelial phenotype and association with microvascular density. Clinical cancer research : an official journal of the American Association for Cancer Research, 12(19), 5648-5658. https://doi.org/10.1158/1078-0432.CCR-06-0852

Purpose: The role for the hypoxia-inducible angiogenic factor adrenomedullin (AM) in tumor growth and progression has been suggested. Calcitonin receptor - like receptor (CL) is a G protein - coupled receptor (GPCR) that mediates effects of AM, but l... Read More about Expression of terminally glycosylated calcitonin receptor - Like receptor in uterine leiomyoma: Endothelial phenotype and association with microvascular density.

Adrenomedullin and CGRP interact with endogenous calcitonin-receptor-like receptor in endothial cells and induce its desensitisation by different mechanism (2006)
Journal Article
Nikitenko, L. L., Blucher, N., Fox, S. B., Bicknell, R., Smith, D. M., & Rees, M. C. (2006). Adrenomedullin and CGRP interact with endogenous calcitonin-receptor-like receptor in endothial cells and induce its desensitisation by different mechanism. Journal of cell science, 119(5), 910-922. https://doi.org/10.1242/jcs.02783

Adrenomedullin (AM) and calcitonin gene-related peptide (CGRP) are related peptides with distinct pharmacological profiles. Calcitonin-receptor-like receptor (CRLR, now known as CL) can function as either an AM receptor or a CGRP receptor, when cotra... Read More about Adrenomedullin and CGRP interact with endogenous calcitonin-receptor-like receptor in endothial cells and induce its desensitisation by different mechanism.