Professor Simon Hart S.Hart@hull.ac.uk
Professor in Respiratory Medicine
A single arm, open-label exploratory clinical trial of azithromycin in pulmonary sarcoidosis
People Involved
Dr Simon Fraser
Prof Michael Crooks m.g.crooks@hull.ac.uk
Professor of Respiratory Medicine
Effects of Azithromycin on Blood Inflammatory Gene Expression and Cytokine Production in Sarcoidosis (2024)
Journal Article
Fraser, S. D., Thackray-Nocera, S., Wright, C., Flockton, R., James, S. R., Crooks, M. G., Kaye, P. M., & Hart, S. P. (2024). Effects of Azithromycin on Blood Inflammatory Gene Expression and Cytokine Production in Sarcoidosis. Lung, https://doi.org/10.1007/s00408-024-00743-wIntroduction: In sarcoidosis granulomas, monocyte-derived macrophages are activated by pro-inflammatory cytokines including TNF and IL-6. Current drug treatment for sarcoidosis aims to suppress inflammation but disabling side effects can ensue. The m... Read More about Effects of Azithromycin on Blood Inflammatory Gene Expression and Cytokine Production in Sarcoidosis.