Is zinc a critical modulator of cyclic nucleotide signalling?

Platelet zinc status regulates prostaglandin-induced signaling, altering thrombus formation (2023)
Journal Article
Coupland, C. A., Naylor-Adamson, L., Booth, Z., Price, T. W., Gil, H. M., Firth, G., Avery, M., Ahmed, Y., Stasiuk, G. J., & Calaminus, S. D. (2023). Platelet zinc status regulates prostaglandin-induced signaling, altering thrombus formation. Journal of thrombosis and haemostasis : JTH, 21(9), 2545-2558. https://doi.org/10.1016/j.jtha.2023.05.008

Background: Approximately 17.3% of the global population exhibits an element of zinc (Zn2+) deficiency. One symptom of Zn2+ deficiency is increased bleeding through impaired hemostasis. Platelets are crucial to hemostasis and are inhibited by endothe... Read More about Platelet zinc status regulates prostaglandin-induced signaling, altering thrombus formation.