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The role of inhibitory and excitatory motor processes in planned scratch responses

People Involved

Dr Emmanuele Tidoni

Profile image of Dr Henning Holle

Dr Henning Holle H.Holle@hull.ac.uk
Reader in Psychology / Leader of Cognitive and Clinical Neuroscience group (https://www.hull.ac.uk/neuroscience)

Project Description

Chronic itch patients are often stuck in a vicious, mutually reinforcing itch-scratch cycle, leading to exacerbation of symptoms and feelings of loss of control over their disease following a scratching bout. The aim of the present project is to break the itch-scratch cycle, by progressing understanding of what gives to urge to scratch when one is experiencing an itch. Whether or not a patient acts out the intention to scratch depends, among other things, on the strength of simultaneous top-down inhibitory processes (e.g., every eczema patient knows they should not scratch). Understanding the neurophysiological basis that gives rise to this urge to scratch or the assumed inhibitory counterforces is not only important for a better theoretical understanding, but is also of fundamental relevance for developing novel interventions that aim to reduce the urge to scratch.

Status Project Complete
Value £3,500.00
Project Dates Sep 1, 2020 - Apr 30, 2023

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