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NAL04-201 - Trevi Therapeutics, Inc. - Refractory Chronic Cough - 4318/0011

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Kappa and Mu Opioid Receptors in Chronic Cough: Current Evidence and Future Treatment (2025)
Journal Article
Birring, S. S., Dicpinigaitis, P. V., Maher, T. M., Mazzone, S. B., Page, C. P., Hawi, A., Sciascia, T., & Morice, A. H. (2025). Kappa and Mu Opioid Receptors in Chronic Cough: Current Evidence and Future Treatment. Lung, 203, Article 62. https://doi.org/10.1007/s00408-025-00812-8

Chronic cough is a significant burden on patient quality of life and is associated with poor health outcomes. Chronic cough may be a result of neural hypersensitivity due to changes in both the peripheral and the central nervous systems, although the... Read More about Kappa and Mu Opioid Receptors in Chronic Cough: Current Evidence and Future Treatment.