All Projects (59)

DRESSINg: DACC in the REduction of Surgical Site INfection Feb 1, 2017 - Jan 31, 2018
A surgical site infection is an infection occurring in the body where surgery has recently taken place. The rates of infection vary according to the type of surgery but may occur in as many as 1 in every 3 or 4 operations. All of these infections cau... Read More about DRESSINg: DACC in the REduction of Surgical Site INfection.

Prognostic Value of 18 FDG PET-CT in Idiopathic Pulmonary Fibrosis Feb 1, 2017 - Dec 31, 2023

Development and application of a multi-scale computational model of sarcoidosis to predict therapeutic approaches for non-self-resolving disease Jun 30, 2017 - Aug 31, 2020
An in silico computational model of sarcoidosis

BATCH: Biomarker-guided duration of Antibiotic Treatment in Children Hospitalised with confirmed or suspected bacterial infection Sep 1, 2017 - Feb 28, 2022

PUMA: Paediatric early warning system (PEWS): Utilisation and Mortality Avoidance. A prospective, mixed methods, before and after study identifying the evidence base for the core components of an effective PEWS and the development of an implementation package for implementation and use in the UK Oct 1, 2017 - Oct 31, 2018
In 2011 a research study compared the child health outcomes and death rate in the UK with other European countries. It was worrying that UK measures of child health were amongst the worst in Europe. It is not clear why that is and further work needs... Read More about PUMA: Paediatric early warning system (PEWS): Utilisation and Mortality Avoidance. A prospective, mixed methods, before and after study identifying the evidence base for the core components of an effective PEWS and the development of an implementation package for implementation and use in the UK.

BRAVO: High grade bladder cancer: a randomised controlled trial of radical cystectomy against intra-vesical immunotherapy – a feasibility study Oct 1, 2017 - Sep 30, 2018
Bladder cancer is a common disease with worse outcomes in Yorkshire than in the rest of the UK. We want to conduct a randomized trial to evaluate the best treatment for aggressive bladder cancer when found at an early stage. This could be complete b... Read More about BRAVO: High grade bladder cancer: a randomised controlled trial of radical cystectomy against intra-vesical immunotherapy – a feasibility study.

LAVA: Thermal ablation versus surgery for patients with colorectal liver metastases Oct 1, 2017 - May 31, 2023

An educational resource about palliative care needs of men with prostate cancer: supporting the patient living with prostate cancer Dec 1, 2017 - Feb 28, 2019

NIFTy: Near Infrared Fluorescence imaging to prevent post-surgical hypoparathyroidism after thyriod surgery - a phase II/III pragmatic, multi-centre rct Oct 1, 2019 - Jul 31, 2024
Parathyroid glands are tiny glands in the neck behind the thyroid gland that control the level of calcium in the blood. More than 12,000 patients undergo thyroid surgery every year in England alone (HES dataset). A common complication of thyroid surg... Read More about NIFTy: Near Infrared Fluorescence imaging to prevent post-surgical hypoparathyroidism after thyriod surgery - a phase II/III pragmatic, multi-centre rct.

Improving outcomes in patient with diabetic foot disease Jun 1, 2018 - May 31, 2019
Diabetes is the fastest growing health crisis of our time. One person with diabetes dies every 6 seconds. In the UK a new person is diagnosed every 2 minutes and care of diabetes currently costs the NHS £1million per hour, every hour. Diabetes is not... Read More about Improving outcomes in patient with diabetic foot disease.

LACES 2: A multicentre, randomised controlled trial of Laparoscopic versus Open Colorectal Surgery in the Acute Setting Apr 1, 2020 - Dec 31, 2025
Approximately 30,000 patients undergo an emergency laparotomy within the NHS yearly. An emergency laparotomy is an open operation which is undertaken for a variety of diseases, a third of those are for diseases affecting the large bowel, including co... Read More about LACES 2: A multicentre, randomised controlled trial of Laparoscopic versus Open Colorectal Surgery in the Acute Setting.

A single arm, open-label exploratory clinical trial of azithromycin in pulmonary sarcoidosis Mar 1, 2019 - Sep 30, 2020
Patients with sarcoidosis need treatment options that improve their disease without causing unacceptable side effects. Currently, steroids tablets are offered for severe sarcoidosis, but side effects can be dangerous and personally distressing, and s... Read More about A single arm, open-label exploratory clinical trial of azithromycin in pulmonary sarcoidosis.

EPaCCS: Electronic Palliative Care Co-ordination Systems (EPaCCS) in end of life care: evaluating their implementation and optimising future service provision. Sep 1, 2020 - Nov 30, 2023
It is not clear how Electronic Palliative Care Co-ordination Systems (EPaCCS) are being implemented across England, what problems healthcare professionals face in using EPaCCS, what views patients and caregivers have on EPaCCS, and how EPaCCS affect... Read More about EPaCCS: Electronic Palliative Care Co-ordination Systems (EPaCCS) in end of life care: evaluating their implementation and optimising future service provision..

GCRF 2019 PPF03: Depression and anxiety in patients with thyroid cancer in China Apr 1, 2019 - Mar 31, 2020
Majority of differentiated thyroid cancer can be successfully treated by thyroidectomy, radioactive iodine treatment and thyrotropin suppression therapy. However, the whole surgical and the first course of radioactive iodine treatment last around one... Read More about GCRF 2019 PPF03: Depression and anxiety in patients with thyroid cancer in China.

PPI for PBP research - Exploring the role, responsibilities and impact of pharmacists working in primary care (GP surgeries) Apr 1, 2019 - Sep 30, 2019
Both local and national initiatives seek to recruit more pharmacists to work in GP practices. Following a successful pilot, NHS England have committed to recruit up to 2000 pharmacists by 2020 to work clinically in general practice settings; this is... Read More about PPI for PBP research - Exploring the role, responsibilities and impact of pharmacists working in primary care (GP surgeries).

Comparing Outcomes of Through knee and Above knee Amputation Apr 17, 2019 - Dec 31, 2021
Project aims: To explore quality of life and rehabilitation outcomes for through knee (TK) amputees and above knee (AK) amputees.

TK amputation is rarely performed despite documented functional benefits and reports that surgical outcomes for dysv... Read More about Comparing Outcomes of Through knee and Above knee Amputation.

Endoscopic vein harvesting - Research Support Funding Aug 1, 2022 - Jul 31, 2023
The long saphenous vein remains the most frequently used conduit for coronary artery bypass grafting. Traditionally, the harvesting of this conduit has been by open incision extending upwards from the ankle in the inner side of the leg up to the groi... Read More about Endoscopic vein harvesting - Research Support Funding.

The Ulsys “smart sock” – transforming venous leg ulcer care with a patient centred electronically assisted self-care compression system. Aug 16, 2019 - Feb 15, 2020

Examining Impact of Local Area Coordination as a Preventative Intervention in Adult Social Care Jul 1, 2021 - Mar 31, 2024
Bid to NIHR RfPB call on Social Care. Examines the impact of LAC interventions compared across 5 cities. Uses both Economic costs/outcomes anlaysis and lived experience participant journeys.

QR - GCRF - PPF15 - Establishing a Platform for Measuring the Effect of Ambient Air Pollution on Maternal and Newborn Health Outcomes in Ghana Nov 1, 2019 - Dec 31, 2020
Air pollution is a leading cause of morbidity and mortality globally. The World Health Organization reports over 90% of global population breathe in polluted air and results in 7 million premature deaths yearly. Yet, due to lack of empirical data on... Read More about QR - GCRF - PPF15 - Establishing a Platform for Measuring the Effect of Ambient Air Pollution on Maternal and Newborn Health Outcomes in Ghana.