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Identification of the Antigens Recognised by Colorectal Cancer Patients Using Sera from Patients Who Exhibit a Crohn’s-like Lymphoid Reaction (2022)
Journal Article
Boncheva, V., Linnebacher, M., Kdimati, S., Draper, H., Orchard, L., Mills, K., …Guinn, B. (2022). Identification of the Antigens Recognised by Colorectal Cancer Patients Using Sera from Patients Who Exhibit a Crohn’s-like Lymphoid Reaction. Biomolecules, 12(8), 1058. https://doi.org/10.3390/biom12081058

A Crohn’s-like lymphoid reaction (CLR) is observed in about 15% of colorectal cancer (CRC) patients and is associated with favourable outcomes. To identify the immune targets recognised by CRC CLR patient sera, we immunoscreened a testes cDNA library... Read More about Identification of the Antigens Recognised by Colorectal Cancer Patients Using Sera from Patients Who Exhibit a Crohn’s-like Lymphoid Reaction.

Just, Reasonable Multiculturalism: Reply to Levey, Newman and Cohen (2022)
Journal Article
Cohen-Almagor, R. (2022). Just, Reasonable Multiculturalism: Reply to Levey, Newman and Cohen. Philosophia, https://doi.org/10.1007/s11406-022-00543-7

This is my reply to the symposium articles, written by Levey, Newman and Cohen. Any critique of Just, Reasonable Multiculturalism should consider the underpinning principles of the theory. I made it clear that the theory is restricted to democracies... Read More about Just, Reasonable Multiculturalism: Reply to Levey, Newman and Cohen.

Portfolio Entrepreneurs: The role of risk (2022)
Book Chapter
Malfense Fierro, A., & Rosa, P. (2022). Portfolio Entrepreneurs: The role of risk. In D. Lingelbach (Ed.), De Gruyter Handbook of Entrepreneurial Finance (75-85). Berlin: De Gruyter. https://doi.org/10.1515/9783110726312

Financial portfolio theory suggests that diversifying through establishing a group of businesses may be an important mechanism to manage and spread risk, but empirical entrepreneurship research on portfolio entrepreneurship has failed to adequately i... Read More about Portfolio Entrepreneurs: The role of risk.

miRNA expression in acute myeloid leukaemia: new targets for therapy? (2022)
Journal Article
Fletcher, D., Brown, E., Javadala, J., Uysal-Onganer, P., & Guinn, B. (in press). miRNA expression in acute myeloid leukaemia: new targets for therapy?. eJHaem, https://doi.org/10.1002/jha2.441

Recent studies have shown that short non-coding RNAs, known as microRNAs (miRNAs) and their dysregulation, are implicated in the pathogenesis of acute myeloid leukaemia (AML). This is due to their role in the control of gene expression in a variety o... Read More about miRNA expression in acute myeloid leukaemia: new targets for therapy?.

Detection of microplastics in human lung tissue using μFTIR spectroscopy (2022)
Journal Article
Jenner, L. C., Rotchell, J. M., Bennett, R. T., Cowen, M., Tentzeris, V., & Sadofsky, L. (2022). Detection of microplastics in human lung tissue using μFTIR spectroscopy. The Science of the total environment, 831, Article 154907. https://doi.org/10.1016/j.scitotenv.2022.154907

Airborne microplastics (MPs) have been sampled globally, and their concentration is known to increase in areas of high human population and activity, especially indoors. Respiratory symptoms and disease following exposure to occupational levels of MP... Read More about Detection of microplastics in human lung tissue using μFTIR spectroscopy.

Identification of biomarkers for the diagnosis and targets for therapy in patients with clear cell ovarian cancer: a systematic literature review (2022)
Journal Article
Butler, H., Saulat, O., & Guinn, B. A. (2022). Identification of biomarkers for the diagnosis and targets for therapy in patients with clear cell ovarian cancer: a systematic literature review. Carcinogenesis, 43(3), 183-189. https://doi.org/10.1093/carcin/bgac012

Clear cell ovarian cancer (CCOC) is a rare type of epithelial cancer often resistant to platinum-based chemotherapy. Biomarkers for the diagnosis of CCOC, and targets for immunotherapy, both have the potential to improve outcomes for patients. Our re... Read More about Identification of biomarkers for the diagnosis and targets for therapy in patients with clear cell ovarian cancer: a systematic literature review.

Combined Metallomics/Transcriptomics Profiling Reveals a Major Role for Metals in Wound Repair (2021)
Journal Article
Wilkinson, H. N., Guinn, B. A., & Hardman, M. J. (2021). Combined Metallomics/Transcriptomics Profiling Reveals a Major Role for Metals in Wound Repair. Frontiers in Cell and Developmental Biology, 9, Article 788596. https://doi.org/10.3389/fcell.2021.788596

Endogenous metals are required for all life, orchestrating the action of diverse cellular processes that are crucial for tissue function. The dynamic wound healing response is underpinned by a plethora of such cellular behaviours, occurring in a time... Read More about Combined Metallomics/Transcriptomics Profiling Reveals a Major Role for Metals in Wound Repair.

Treatied space: North American indigenous treaties in a global context (2021)
Book Chapter
Porter, J. (2021). Treatied space: North American indigenous treaties in a global context. In A. McGrath, & L. Russell (Eds.), The Routledge Companion to Global Indigenous History (259-278). London: Taylor & Francis (Routledge). https://doi.org/10.4324/9781315181929

All communities and individuals living on North American land are, in a geo-political sense, ‘treaty people’ and attention to treaty history is vital to the challenge of addressing the profound environmental, technological, and resource-use changes o... Read More about Treatied space: North American indigenous treaties in a global context.

Survivin’ acute myeloid leukaemia—a personalised target for inv(16) patients (2021)
Journal Article
Greiner, J., Brown, E., Bullinger, L., Hills, R. K., Morris, V., Döhner, H., …Guinn, B. A. (2021). Survivin’ acute myeloid leukaemia—a personalised target for inv(16) patients. International Journal of Molecular Sciences, 22(19), Article 10482. https://doi.org/10.3390/ijms221910482

Abstract: Despite recent advances in therapies including immunotherapy, patients with acute myeloid leukaemia (AML) still experience relatively poor survival rates. The Inhibition of Apoptosis (IAP) family member, survivin, also known by its gene and... Read More about Survivin’ acute myeloid leukaemia—a personalised target for inv(16) patients.

Coercion (2021)
Journal Article
Cohen-Almagor, R. (2021). Coercion. Open Journal of Philosophy, 11(03), 386-409. https://doi.org/10.4236/ojpp.2021.113027

Coercion involves two or more parties who are in conflict and whose relationships are complex and uneasy. Generally speaking, people resent coercion and, when possible, rebel against it. This paper differentiates between circumstantial coercion and p... Read More about Coercion.

Sexual and reproductive health knowledge and behaviour of adolescent boys and girls aged 10-19 years in western Kenya: Evidence from a cross-sectional pilot survey (2021)
Journal Article
Magadi, M., Kaseje, D., Kaseje, M., Ochola-Odhiambo, P., Ogutu-Owii, S., Wafula, C., …Smith, L. (2021). Sexual and reproductive health knowledge and behaviour of adolescent boys and girls aged 10-19 years in western Kenya: Evidence from a cross-sectional pilot survey. Journal of biosocial science, https://doi.org/10.1017/S0021932021000353

This paper reports findings of a pilot survey of adolescent sexual and reproductive health (ASRH) knowledge and behaviour in Homabay County of western Kenya. The study was based on a cross-sectional survey of 523 male and female adolescents aged 10-1... Read More about Sexual and reproductive health knowledge and behaviour of adolescent boys and girls aged 10-19 years in western Kenya: Evidence from a cross-sectional pilot survey.

A novel HAGE/WT-1 ImmunoBody® vaccine combination enhances anti-tumour responses when compared to either vaccine alone. (2021)
Journal Article
Almshayakhchi, R., Nagarajan, D., Vadakekolathu, J., Guinn, B., Reeder, S., Brentville, V., …McArdle, S. (in press). A novel HAGE/WT-1 ImmunoBody® vaccine combination enhances anti-tumour responses when compared to either vaccine alone. Frontiers in Oncology, 11, https://doi.org/10.3389/fonc.2021.636977

Many cancers, including myeloid leukaemia express the cancer testis antigen (CTA) DDX43 (HAGE) and/or the oncogene Wilms' tumour (WT1). Here we demonstrate that HAGE/WT1-ImmunoBody® vaccines derived T-cells can kill ex-vivo human CML cell lines expre... Read More about A novel HAGE/WT-1 ImmunoBody® vaccine combination enhances anti-tumour responses when compared to either vaccine alone..

Supply Chain Management Systems in Africa: insights from Nigeria. (2021)
Book Chapter
Oyedijo, A., Adams, K., & Koukpaki, S. (2021). Supply Chain Management Systems in Africa: insights from Nigeria. In J. B. Abugre, E. Osabutey, & S. Sigué (Eds.), Business in Africa in the Era of Digital Technology: Essays in Honour of Professor William Darley. Springer. https://doi.org/10.1007/978-3-030-70538-1

This chapter investigates the barriers and driving forces of supply chain collaboration in Nigeria as prior research has not adequately explored this issue in developing countries. Using an in-depth qualitative interviews conducted with purchasing an... Read More about Supply Chain Management Systems in Africa: insights from Nigeria..

Guidance On The Use Of Esketamine Nasal Spray For Treatment Resistant Depression (2021)
Other
White, J., & Feetam, C. (2021). Guidance On The Use Of Esketamine Nasal Spray For Treatment Resistant Depression. Janssen Medical Cloud for UK Healthcare Professionals

This guidance was commissioned by Janssen-Cilag Ltd as part of an extensive programme of work to support practitioners across the UK to apply best practice to the supervised self-administration of esketamine nasal spray. The document was generated wi... Read More about Guidance On The Use Of Esketamine Nasal Spray For Treatment Resistant Depression.

The Health Improvement Profile for people with severe mental illness: Feasibility of a secondary analysis to make international comparisons (2021)
Journal Article
Bos, D., Gray, R., Meepring, S., White, J., Foland, K., & Bressington, D. (in press). The Health Improvement Profile for people with severe mental illness: Feasibility of a secondary analysis to make international comparisons. Journal of psychiatric and mental health nursing, https://doi.org/10.1111/jpm.12748

Abstract: Introduction To date, no studies have contrasted physical health profiles of people with severe mental illness (SMI) in different countries. Aim To evaluate feasibility of using the Health Improvement Profile (HIP) to compare and contrast p... Read More about The Health Improvement Profile for people with severe mental illness: Feasibility of a secondary analysis to make international comparisons.

Taking Profound Offence Seriously - Freedom Of Speech V. Human Dignity (2020)
Journal Article
Cohen-Almagor, R. (2020). Taking Profound Offence Seriously - Freedom Of Speech V. Human Dignity. Journal of hate studies, 16(1), 1-11. https://doi.org/10.33972/jhs.152

This study discusses the issue of offence to sensibilities as possible grounds for limiting freedom of expression. This issue is constantly brought to the public agenda, as for example, in the limitation imposed in Israel on the playing of Richard Wa... Read More about Taking Profound Offence Seriously - Freedom Of Speech V. Human Dignity.

Seventeen Pieces: Displacement, Misplacement and Conservation (2020)
Journal Article
Merali, Y., Mourad, K., & Ghanem, M. (2020). Seventeen Pieces: Displacement, Misplacement and Conservation. New England Journal of Public Policy, 32(2), Article 7

This article explores the systemic importance of art in the conservation of images, historical reference, and cultural meaning as displaced victims of humanitarian crises make the transition from the land of their birth to a new country with a differ... Read More about Seventeen Pieces: Displacement, Misplacement and Conservation.

Rereading Ruins: Edmund Spenser and Scottish Presbyterianism (2020)
Book Chapter
Mottram, S. (2020). Rereading Ruins: Edmund Spenser and Scottish Presbyterianism. In A. Walsham, B. Wallace, C. Law, & B. Cummings (Eds.), Memory and the English Reformation (223-237). Cambridge: Cambridge University Press

With a focus on Edmund Spenser, this chapter explores representations of ruined monasteries within (New) English protestant writing of c.1590-1642. Monastic ruins are visible mnemonics of British-Irish reformation, and protestants express surprisingl... Read More about Rereading Ruins: Edmund Spenser and Scottish Presbyterianism.

Identification of Genes Whose Expression Overlaps Age Boundaries and Correlates with Risk Groups in Paediatric and Adult Acute Myeloid Leukaemia (2020)
Journal Article
Davis, L., Mills, K. I., Orchard, K. H., & Guinn, B. A. (2020). Identification of Genes Whose Expression Overlaps Age Boundaries and Correlates with Risk Groups in Paediatric and Adult Acute Myeloid Leukaemia. Cancers, 12(10), 1-22. https://doi.org/10.3390/cancers12102769

Few studies have compared gene expression in paediatric and adult acute myeloid leukaemia (AML). In this study, we have analysed mRNA-sequencing data from two publicly accessible databases: (1) National Cancer Institute's Therapeutically Applicable R... Read More about Identification of Genes Whose Expression Overlaps Age Boundaries and Correlates with Risk Groups in Paediatric and Adult Acute Myeloid Leukaemia.