Immune Responses to Persistent or Recurrent Antigens: Implications for Immunological Memory and Immunotherapy
(2021)
Journal Article
Caserta, S., & Pera, A. (2021). Immune Responses to Persistent or Recurrent Antigens: Implications for Immunological Memory and Immunotherapy. Frontiers in immunology, 12, Article 643989. https://doi.org/10.3389/fimmu.2021.643989
Outputs (77)
Hippo STK kinases drive metabolic derangement (2021)
Journal Article
Maedler, K., & Ardestani, A. (2021). Hippo STK kinases drive metabolic derangement. Nature Metabolism, 3(3), 295-296. https://doi.org/10.1038/s42255-021-00370-2Obesity is associated with mitochondrial dysfunction and chronic metabolic derailment. Cho et al. report that elevated adipose expression of the Hippo kinases STK3 and STK4 (STK3/4) in obesity and type 2 diabetes decreases the mass and oxidative capa... Read More about Hippo STK kinases drive metabolic derangement.
An evaluation of inkjet printed amino acid fingerprint test targets for ninhydrin process monitoring − and some observations (2021)
Journal Article
Croxton, R., Kent, T., Littlewood, A., & Smith, M. (2021). An evaluation of inkjet printed amino acid fingerprint test targets for ninhydrin process monitoring − and some observations. Forensic Science International, 321, Article 110741. https://doi.org/10.1016/j.forsciint.2021.110741Ninhydrin was implemented as the primary police method of developing latent fingermarks on paper, cardboard and some other porous surfaces from the late 1960s. Some researchers have used individual amino acids, or mixtures of amino acids, as a method... Read More about An evaluation of inkjet printed amino acid fingerprint test targets for ninhydrin process monitoring − and some observations.
A muscle growth-promoting treatment based on the attenuation of activin/myostatin signalling results in long-term testicular abnormalities (2021)
Journal Article
Vaughan, D., Mitchell, R., Kretz, O., Chambers, D., Lalowski, M., Amthor, H., Ritvos, O., Pasternack, A., Matsakas, A., Vaiyapuri, S., Huber, T. B., Denecke, B., Mukherjee, A., Widera, D., & Patel, K. (2021). A muscle growth-promoting treatment based on the attenuation of activin/myostatin signalling results in long-term testicular abnormalities. Disease Models and Mechanisms, 14(2), Article dmm047555. https://doi.org/10.1242/dmm.047555© 2021. Published by The Company of Biologists Ltd. Activin/myostatin signalling acts to induce skeletal muscle atrophy in adult mammals by inhibiting protein synthesis as well as promoting protein and organelle turnover. Numerous strategies have bee... Read More about A muscle growth-promoting treatment based on the attenuation of activin/myostatin signalling results in long-term testicular abnormalities.
Protective effects of dapagliflozin against oxidative stress-induced cell injury in human proximal tubular cells (2021)
Journal Article
Zaibi, N., Li, P., & Xu, S.-Z. (in press). Protective effects of dapagliflozin against oxidative stress-induced cell injury in human proximal tubular cells. PLoS ONE, 16(2), Article e0247234. https://doi.org/10.1371/journal.pone.0247234Elevated reactive oxygen species (ROS) in type 2 diabetes cause cellular damage in many organs. Recently, the new class of glucose-lowering agents, SGLT-2 inhibitors, have been shown to reduce the risk of developing diabetic complications; however, t... Read More about Protective effects of dapagliflozin against oxidative stress-induced cell injury in human proximal tubular cells.
Ibrutinib does not reverse disease- and treatment-related hypogammaglobulinaemia associated with chronic lymphocytic leukemia (2021)
Journal Article
Khan, S., Durairaj, S., Phumphukhieo, P., Holding, S., & Allsup, D. (2021). Ibrutinib does not reverse disease- and treatment-related hypogammaglobulinaemia associated with chronic lymphocytic leukemia. Leukemia & Lymphoma, 1-8. https://doi.org/10.1080/10428194.2021.1885662
Human ex vivo wound model and whole-mount staining approach to accurately evaluate skin repair (2021)
Journal Article
Wilkinson, H. N., Kidd, A. S., Roberts, E. R., & Hardman, M. J. (2021). Human ex vivo wound model and whole-mount staining approach to accurately evaluate skin repair. Journal of visualized experiments : JoVE, 168, Article e62326. https://doi.org/10.3791/62326© 2021 JoVE Creative Commons. Chronic non-healing wounds, which primarily affect the elderly and diabetic, are a significant area of clinical unmet need. Unfortunately, current chronic wound treatments are inadequate, while available pre-clinical mod... Read More about Human ex vivo wound model and whole-mount staining approach to accurately evaluate skin repair.
NIR-quantum dots in biomedical imaging and their future (2021)
Journal Article
Gil, H. M., Price, T. W., Chelani, K., Bouillard, J. S. G., Calaminus, S. D., & Stasiuk, G. J. (2021). NIR-quantum dots in biomedical imaging and their future. iScience, 24(3), Article 102189. https://doi.org/10.1016/j.isci.2021.102189Fluorescence imaging has gathered interest over the recent years for its real-time response and high sensitivity. Developing probes for this modality has proven to be a challenge. Quantum dots (QDs) are colloidal nanoparticles that possess unique opt... Read More about NIR-quantum dots in biomedical imaging and their future.
Recent Advancements in Hematology: Knowledge, Methods and Dissemination, Part 2 (2021)
Journal Article
Corre, J., Sabbah, M., Schjesvold, F., Zeidan, A. M., Buccisano, F., Sallman, D., Mazzucato, M., Madden, L. A., Martini, M., Van Breda, E., Dolcetti, R., Busca, A., Cook, G., Onida, F., Versari, A., Kiladjian, J. J., Walter, R. B., Garderet, L., Robin, M., & Signore, A. (2021). Recent Advancements in Hematology: Knowledge, Methods and Dissemination, Part 2. Hemato, 2(1), 79-88. https://doi.org/10.3390/hemato2010004
Revascularisation of type 2 diabetics with coronary artery disease: Insights and therapeutic targeting of O-GlcNAcylation (2021)
Journal Article
Bolanle, I. O., Riches-Suman, K., Loubani, M., Williamson, R., & Palmer, T. M. (2021). Revascularisation of type 2 diabetics with coronary artery disease: Insights and therapeutic targeting of O-GlcNAcylation. Nutrition, metabolism, and cardiovascular diseases : NMCD, https://doi.org/10.1016/j.numecd.2021.01.017Background and Aim:
Coronary artery bypass graft (CABG) using autologous saphenous vein continues to be a gold standard procedure to restore the supply of oxygen-rich blood to the heart muscles in coronary artery disease (CAD) patients with or with... Read More about Revascularisation of type 2 diabetics with coronary artery disease: Insights and therapeutic targeting of O-GlcNAcylation.