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Outputs (1035)

Determination of the role of WSB-1 in breast cancer and metastasis to the bone (2024)
Thesis
Lovell, S. (2024). Determination of the role of WSB-1 in breast cancer and metastasis to the bone. (Thesis). University of Hull. https://hull-repository.worktribe.com/output/5086180

Breast cancer is the second most common cause of female-related deaths in the United Kingdom with metastatic spread the main reason for treatment failure and cancer-related deaths. The bone is the most frequent site of secondary cancer, significantly... Read More about Determination of the role of WSB-1 in breast cancer and metastasis to the bone.

The morphology and stability of the oxygen pulse curve during cardiopulmonary exercise testing (2024)
Journal Article
Nickolay, T., Ingle, L., Hoye, A., Garrett, A. T., & Gleadall-Siddall, D. O. (2025). The morphology and stability of the oxygen pulse curve during cardiopulmonary exercise testing. Science & Sports, 40(3), 239-247. https://doi.org/10.1016/j.scispo.2024.10.003

Objectives: This study aimed to assess the relative and absolute reliability (agreement) of various parameters derived from the oxygen pulse ( O˙2Pulse) curve during cardiopulmonary exercise testing (CPET), a tool critical for evaluating cardiopulmon... Read More about The morphology and stability of the oxygen pulse curve during cardiopulmonary exercise testing.

‘How Long Do I Have?’ – Examining survival outcomes in laryngeal cancer patients managed with non-curative intent in Northern UK: Insights from the Northern Head & Neck Cancer Alliance Retrospective Study (2024)
Journal Article
Rajgor, A., Hurley, R., Douglas, C. M., Paterson, C., Moor, J., Lester, S., Sionis, S., Davies, K., O'Hara, J., Inman, G., Jones, T., Hamilton, D. W., Hill, S., O’Neill, S., McLoughlin, A., Jose, J., Wong, W., Ho, M., Horne, D., Homer, J., …Mandrik, O. (in press). ‘How Long Do I Have?’ – Examining survival outcomes in laryngeal cancer patients managed with non-curative intent in Northern UK: Insights from the Northern Head & Neck Cancer Alliance Retrospective Study. Clinical otolaryngology, https://doi.org/10.1111/coa.14260

Introduction: Historically, 15% of laryngeal cancer patients undergo non-curative management, but pragmatic data on this group are limited. This information is crucial to help patients make informed decisions about their care. Supported by the Northe... Read More about ‘How Long Do I Have?’ – Examining survival outcomes in laryngeal cancer patients managed with non-curative intent in Northern UK: Insights from the Northern Head & Neck Cancer Alliance Retrospective Study.

The Impact of Attendance on Academic Performance in Forensic Science Undergraduate Programs: A Cohort Analysis (2024)
Journal Article
Preece, D. (2024). The Impact of Attendance on Academic Performance in Forensic Science Undergraduate Programs: A Cohort Analysis. Journal of Forensic Science Education, 6(2), 1-10

Attendance in educational settings has long been regarded as a crucial factor influencing student performance and outcomes. In the field of forensic science, where both theoretical knowledge and practical skills are essential, regular attendance in l... Read More about The Impact of Attendance on Academic Performance in Forensic Science Undergraduate Programs: A Cohort Analysis.

PEGylation of indium phosphide quantum dots prevents quantum dot mediated platelet activation (2024)
Journal Article
Naylor-Adamson, L., Price, T. W., Booth, Z., Leonard, S. V. L., Gallo, J., Tung, L. D., Harvell-Smith, S., Thi Kim Thanh, N., Aslam, Z., Allsup, D., Hondow, N., Chamberlain, T., Schneider, J. E., Naseem, K., Bouillard, J. S. G., Stasiuk, G. J., & Calaminus, S. D. (in press). PEGylation of indium phosphide quantum dots prevents quantum dot mediated platelet activation. Journal of Materials Chemistry B, https://doi.org/10.1039/d4tb01334d

Quantum dots (QDs) are semiconducting inorganic nanocrystals, that have garnered interest in biological and medical spheres due, to their potential benefits in biomedical imaging and drug-delivery systems. Indium phosphide QDs shelled with zinc sulph... Read More about PEGylation of indium phosphide quantum dots prevents quantum dot mediated platelet activation.

α-Synuclein Deletion Impairs Platelet Function: A Role for SNARE Complex Assembly (2024)
Journal Article
Sennett, C., Jia, W., Khalil, J. S., Hindle, M. S., Coupland, C., Calaminus, S. D., Langer, J. D., Frost, S., Naseem, K. M., Rivero, F., Ninkina, N., Buchman, V., & Aburima, A. (2024). α-Synuclein Deletion Impairs Platelet Function: A Role for SNARE Complex Assembly. Cells, 13(24), Article 2089. https://doi.org/10.3390/cells13242089

Granule secretion is an essential platelet function that contributes not only to haemostasis but also to wound healing, inflammation, and atherosclerosis. Granule secretion from platelets is facilitated, at least in part, by Soluble N-ethylmaleimide-... Read More about α-Synuclein Deletion Impairs Platelet Function: A Role for SNARE Complex Assembly.

Tissue factor signalling modifies the expression and regulation of G1/S checkpoint regulators: Implications during injury and prolonged inflammation (2024)
Journal Article
Featherby, S., Faulkner, E., & Ettelaie, C. (2025). Tissue factor signalling modifies the expression and regulation of G1/S checkpoint regulators: Implications during injury and prolonged inflammation. Molecular Medicine Reports, 31(2), Article 39. https://doi.org/10.3892/mmr.2024.13404

Tissue factor (TF) possesses additional physiological functions beyond initiating the coagulation cascade. Cellular signals initiated by cellular TF or on contact with TF-containing microvesicles, contribute to wound healing through regulating a numb... Read More about Tissue factor signalling modifies the expression and regulation of G1/S checkpoint regulators: Implications during injury and prolonged inflammation.

High‐Risk Chronic Lymphocytic Leukemia Complicating the Course of Imatinib‐Treated Chronic Myeloid Leukemia: Successful Disease Management With Dual Tyrosine Kinase Inhibition (2024)
Journal Article
James, D., Green, S., Molica, S., & Allsup, D. (2024). High‐Risk Chronic Lymphocytic Leukemia Complicating the Course of Imatinib‐Treated Chronic Myeloid Leukemia: Successful Disease Management With Dual Tyrosine Kinase Inhibition. Case Reports in Hematology, 2024, Article 1813512. https://doi.org/10.1155/2024/1813512

The coexistence of chronic myeloid leukemia (CML) and chronic lymphocytic leukemia (CLL) in the same patient is exceedingly rare, with only a few cases reported in the literature. Here, we report a patient with CML who, having achieved a major molecu... Read More about High‐Risk Chronic Lymphocytic Leukemia Complicating the Course of Imatinib‐Treated Chronic Myeloid Leukemia: Successful Disease Management With Dual Tyrosine Kinase Inhibition.