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Rapid, multistep on-chip DNA hybridisation in continuous flow on magnetic particles (2010)
Journal Article
Vojtíšek, M., Iles, A., & Pamme, N. (2010). Rapid, multistep on-chip DNA hybridisation in continuous flow on magnetic particles. Biosensors & bioelectronics, 25(9), 2172-2176. https://doi.org/10.1016/j.bios.2010.01.034

DNA hybridisation is an important tool for bioanalytical research and clinical diagnostics; conventional methods, however, require long incubation times and numerous washing steps, rendering the procedure time consuming and labour intensive. In this... Read More about Rapid, multistep on-chip DNA hybridisation in continuous flow on magnetic particles.

The importance of particle type selection and temperature control for on-chip free-flow magnetophoresis (2009)
Journal Article
Tarn, M. D., Peyman, S. A., Robert, D., Iles, A., Wilhelm, C., & Pamme, N. (2009). The importance of particle type selection and temperature control for on-chip free-flow magnetophoresis. Journal of Magnetism and Magnetic Materials, 321(24), 4115-4122. https://doi.org/10.1016/j.jmmm.2009.08.016

Free-flow magnetophoresis is becoming a popular technique for the separation and manipulation of magnetic particles and materials in microsystems. A wide variety of magnetic particles are commercially available that differ greatly in size and in magn... Read More about The importance of particle type selection and temperature control for on-chip free-flow magnetophoresis.

Mobile magnetic particles as solid-supports for rapid surface-based bioanalysis in continuous flow (2009)
Journal Article
Peyman, S. A., Iles, A., & Pamme, N. (2009). Mobile magnetic particles as solid-supports for rapid surface-based bioanalysis in continuous flow. Lab on a chip, 9(21), 3110-3117. https://doi.org/10.1039/b904724g

An extremely versatile microfluidic device is demonstrated in which multi-step (bio) chemical procedures can be performed in continuous flow. The system operates by generating several co-laminar flow streams, which contain reagents for specific (bio)... Read More about Mobile magnetic particles as solid-supports for rapid surface-based bioanalysis in continuous flow.

Diamagnetic repulsion—A versatile tool for label-free particle handling in microfluidic devices (2009)
Journal Article
Peyman, S. A., Kwan, E. Y., Margarson, O., Iles, A., & Pamme, N. (2009). Diamagnetic repulsion—A versatile tool for label-free particle handling in microfluidic devices. Journal of Chromatography A, 1216(52), 9055-9062. https://doi.org/10.1016/j.chroma.2009.06.039

We report the exploration of diamagnetic repulsion forces for the selective manipulation of microparticles inside microfluidic devices. Diamagnetic materials such as polymers are repelled from magnetic fields, an effect greatly enhanced by suspending... Read More about Diamagnetic repulsion—A versatile tool for label-free particle handling in microfluidic devices.

Rapid on-chip multi-step (bio)chemical procedures in continuous flow - manoeuvring particles through co-laminar reagent streams (2008)
Journal Article
Peyman, S. A., Iles, A., & Pamme, N. (2008). Rapid on-chip multi-step (bio)chemical procedures in continuous flow - manoeuvring particles through co-laminar reagent streams. Chemical communications : Chem comm / the Royal Society of Chemistry, 1220-1222. https://doi.org/10.1039/b716532c

We introduce a novel and extremely versatile microfluidic platform in which tedious multi-step biochemical processes can be performed in continuous flow within a fraction of the time required for conventional methods.

CFD analysis and experimental validation of magnetic droplet generation and deflection across multilaminar flow streams
Presentation / Conference Contribution
Gómez-Pastora, J., Karampelas, I. H., Alorabi, A. Q., Tarn, M. D., Bringas, E., Iles, A., Paunov, V. N., Pamme, N., Furlani, E. P., & Ortiz, I. (2018, June). CFD analysis and experimental validation of magnetic droplet generation and deflection across multilaminar flow streams. Presented at TechConnect Briefs 2018 - Advanced Materials

© 2018 OOSV. All rights reserved. The use of droplet-based microfluidic systems has increased in the last decade due to the advantages these systems present such as compatibility with many chemical and biological reagents, capability of performing a... Read More about CFD analysis and experimental validation of magnetic droplet generation and deflection across multilaminar flow streams.