Outputs (190)

Immunotherapeutic Potential of Mutated NPM1 for the Treatment of Acute Myeloid Leukemia (2024)
Journal Article
Greiner, J., Mohamed, E., Fletcher, D. M., Schuler, P. J., Schrezenmeier, H., Götz, M., & Guinn, B. A. (2024). Immunotherapeutic Potential of Mutated NPM1 for the Treatment of Acute Myeloid Leukemia. Cancers, 16(20), Article 3443. https://doi.org/10.3390/cancers16203443

Acute myeloid leukemia (AML) is a malignant disease of the blood and bone marrow that is characterized by uncontrolled clonal proliferation of abnormal myeloid progenitor cells. Nucleophosmin 1 (NPM1) gene mutations are the most common genetic abnorm... Read More about Immunotherapeutic Potential of Mutated NPM1 for the Treatment of Acute Myeloid Leukemia.

The environmental dependence of the stellar mass-gas metallicity relation in Horizon Run 5 (2024)
Journal Article
Rowntree, A., Singh, A., Vincenzo, F., Gibson, B. K., Gouin, C., Galárrag a-Espinosa, D., Lee, J., Kim, J., Laigle, C., Park, C., Pichon, C., Few, G., Hong, S. E., & Kim, Y. (2024). The environmental dependence of the stellar mass-gas metallicity relation in Horizon Run 5. Monthly notices of the Royal Astronomical Society, 531(4), 3858-3875. https://doi.org/10.1093/mnras/stae1384

Metallicity offers a unique window into the baryonic history of the cosmos, being instrumental in probing evolutionary processes in galaxies between different cosmic environments. We aim to quantify the contribution of these environments to the scatt... Read More about The environmental dependence of the stellar mass-gas metallicity relation in Horizon Run 5.

Can tumour antigens act as biomarkers for the early detection of non-small cell lung cancer? (2024)
Journal Article
Mohamed, E., Fletcher, D., Hart, S., & Guinn, B.-A. (2024). Can tumour antigens act as biomarkers for the early detection of non-small cell lung cancer?. Onco, 4(2), 87-100. https://doi.org/10.3390/onco4020008

Lung cancer (LC) is one of the leading causes of cancer-related deaths. Pulmonary nodules are one of the risk factors and their discovery rate has been increasing due to enhanced performance of chest CT scans but more than 90% are non-malignant causi... Read More about Can tumour antigens act as biomarkers for the early detection of non-small cell lung cancer?.

Analysis-on-a-roll platforms towards automated and high frequency in-situ sensing of natural geochemical fluxes (2024)
Thesis
Iurkov, A. Analysis-on-a-roll platforms towards automated and high frequency in-situ sensing of natural geochemical fluxes. (Thesis). University of Hull. https://hull-repository.worktribe.com/output/4702966

In the context of the rapidly intensifying crisis of climate change, the intricate dynamics of Earth's ecosystems have assumed a paramount significance. The carbon cycle plays a significant role in the dynamics of the earth’s ecosystem, and anthropog... Read More about Analysis-on-a-roll platforms towards automated and high frequency in-situ sensing of natural geochemical fluxes.

Identification of tumour anitgens that may facilitate effective cancer detection and treatment (2024)
Thesis
Mohamed, E. Identification of tumour anitgens that may facilitate effective cancer detection and treatment. (Thesis). University of Hull. https://hull-repository.worktribe.com/output/4866442

Tumour antigens (TAs) play a crucial role in terms of cancer diagnosis and targets for therapy. As TAs are normally expressed in restricted tissues such as testis, sensitivity and specificity may not be ideal, but they could still represent good biom... Read More about Identification of tumour anitgens that may facilitate effective cancer detection and treatment.

Identification of biomarkers for the early detection of non-small cell lung cancer: a systematic review and meta-analysis (2023)
Journal Article
Mohamed, E., García Martínez, D. J., Hosseini, M. S., Yoong, S. Q., Fletcher, D., Hart, S., & Guinn, B. A. (2024). Identification of biomarkers for the early detection of non-small cell lung cancer: a systematic review and meta-analysis. Carcinogenesis, 45(1-2), Article bgad091. https://doi.org/10.1093/carcin/bgad091

Lung cancer (LC) causes few symptoms in the earliest stages, leading to one of the highest mortality rates among cancers. Low-dose computerised tomography (LDCT) is used to screen high-risk individuals, reducing the mortality rate by 20%. However, LD... Read More about Identification of biomarkers for the early detection of non-small cell lung cancer: a systematic review and meta-analysis.

Mixtures of sediment chemical contaminants at freshwater sampling sites across Europe with different contaminant burdens (2023)
Journal Article
Richardson, S., Mayes, W. M., Faetsch, S., Hetjens, H., Teuchies, J., Walker, P., Heitmann, K., Welham, K., Moore, D., Bervoets, L., Kay, P., Duffus, W., Smith, N., De Cooman, W., Elst, R., Ryken, E., Rotchell, J. M., & Heise, S. (2023). Mixtures of sediment chemical contaminants at freshwater sampling sites across Europe with different contaminant burdens. Science of the Total Environment, 891, Article 164280. https://doi.org/10.1016/j.scitotenv.2023.164280

Extended chemical analyses of fluvial sediments were undertaken to establish the key pollutant pressures and mixtures present across nine European Union inland waterways. A wide range of chemical components and physical parameters were investigated i... Read More about Mixtures of sediment chemical contaminants at freshwater sampling sites across Europe with different contaminant burdens.

Investigating the effects of arginine methylation inhibitors on microdissected brain tumour biopsies maintained in a miniaturised perfusion system (2023)
Journal Article
Barry, A., Samuel, S. F., Hosni, I., Moursi, A., Feugere, L., Sennett, C. J., Deepak, S., Achawal, S., Rajaraman, C., Iles, A., Wollenberg Valero, K. C., Scott, I. S., Green, V., Stead, L. F., Greenman, J., Wade, M. A., & Beltran-Alvarez, P. (2023). Investigating the effects of arginine methylation inhibitors on microdissected brain tumour biopsies maintained in a miniaturised perfusion system. Lab on a chip, 23(11), 2664-2682. https://doi.org/10.1039/d3lc00204g

Arginine methylation is a post-translational modification that consists of the transfer of one or two methyl (CH3) groups to arginine residues in proteins. Several types of arginine methylation occur, namely monomethylation, symmetric dimethylation a... Read More about Investigating the effects of arginine methylation inhibitors on microdissected brain tumour biopsies maintained in a miniaturised perfusion system.

Detection of microplastics in human saphenous vein tissue using μFTIR: a pilot study (2023)
Journal Article
Rotchell, J. M., Jenner, L. C., Chapman, E., Bennett, R., Bolanle, I. O., Loubani, M., Sadofsky, L., & Palmer, T. (2023). Detection of microplastics in human saphenous vein tissue using μFTIR: a pilot study. PLoS ONE, 18(2), Article e0280594. https://doi.org/10.1371/journal.pone.0280594

Microplastics (MPs) are ubiquitous in the environment, in the human food chain, and have been recently detected in blood and lung tissues. To undertake a pilot analysis of MP contamination in human vein tissue samples with respect to their presence (... Read More about Detection of microplastics in human saphenous vein tissue using μFTIR: a pilot study.

Electronic Structure and Optical Properties of Strained Type-II InAsxSb1-x/InAs Quantum Dots for Mid-Infrared Applications (2023)
Journal Article
Yeap, G. H., Rybchenko, S., Itskevich, I., Haywood, S., Carrington, P., & Krier, A. (2023). Electronic Structure and Optical Properties of Strained Type-II InAsxSb1-x/InAs Quantum Dots for Mid-Infrared Applications. Defect and Diffusion Forum, 425, 3-8. https://doi.org/10.4028/p-72o15p

InSb-based self-assembled quantum dots (SAQDs) are very promising for the mid-infrared (3-5 μm) optical range. We have analysed the electronic structure and optical properties of InAsxSb1- x/InAs dots. In this paper, we present the results of the mod... Read More about Electronic Structure and Optical Properties of Strained Type-II InAsxSb1-x/InAs Quantum Dots for Mid-Infrared Applications.