Outputs (208)

Adult B-Cell Acute Lymphoblastic Leukaemia Antigens and Enriched Pathways Identify New Targets for Therapy (2025)
Journal Article
Mohamed, E., Goodman, S., Cooksey, L., Fletcher, D. M., Dean, O., Boncheva, V. B., Mills, K. I., Orchard, K. H., & Guinn, B.-A. (2025). Adult B-Cell Acute Lymphoblastic Leukaemia Antigens and Enriched Pathways Identify New Targets for Therapy. Onco, 5(2), Article 19. https://doi.org/10.3390/onco5020019

Background: Adult B-cell acute lymphoblastic leukaemia (aB-ALL) is charac-terised by abnormal differentiation and proliferation of lymphoid progenitors. Despite a significant improvement in relapse-free and overall survival for children with BALL , a... Read More about Adult B-Cell Acute Lymphoblastic Leukaemia Antigens and Enriched Pathways Identify New Targets for Therapy.

Dynamic co-evolution of transposable elements and the piRNA pathway in African cichlid fishes (2025)
Journal Article
Almeida, M. V., Blumer, M., Yuan, C. U., Sierra, P., Price, J. L., Quah, F. X., Friman, A., Dallaire, A., Vernaz, G., Putman, A. L., Smith, A. M., Joyce, D. A., Butter, F., Haase, A. D., Durbin, R., Santos, M. E., & Miska, E. A. (2025). Dynamic co-evolution of transposable elements and the piRNA pathway in African cichlid fishes. Genome Biology, 26(1), Article 14. https://doi.org/10.1186/s13059-025-03475-z

BACKGROUND: East African cichlid fishes have diversified in an explosive fashion, but the (epi)genetic basis of the phenotypic diversity of these fishes remains largely unknown. Although transposable elements (TEs) have been associated with phenotypi... Read More about Dynamic co-evolution of transposable elements and the piRNA pathway in African cichlid fishes.

Airborne microplastic monitoring: developing a simplified outdoor sampling approach using pollen monitoring equipment (2024)
Journal Article
Chapman, E., Liddle, C. R., Williams, B., Hilmer, E., Quick, L. J., Garcia, A. G., Suárez, D. C., White, D., Bunting, M. J., Walker, P., Cabaneros, S. M. S., Kinnersley, R., Hansen, M. F., Atherall, C. A., & Rotchell, J. M. (2024). Airborne microplastic monitoring: developing a simplified outdoor sampling approach using pollen monitoring equipment. Journal of hazardous materials, 480, Article 136129. https://doi.org/10.1016/j.jhazmat.2024.136129

A novel, yet simple, airborne microplastic (MP) sampling approach using global pollen monitoring equipment was applied to identify, characterise and quantify outdoor airborne MPs for the first time. Modification of Burkard spore trap tape adhesive pr... Read More about Airborne microplastic monitoring: developing a simplified outdoor sampling approach using pollen monitoring equipment.

Immunotherapeutic Potential of Mutated NPM1 for the Treatment of Acute Myeloid Leukemia (2024)
Journal Article
Greiner, J., Mohamed, E., Fletcher, D. M., Schuler, P. J., Schrezenmeier, H., Götz, M., & Guinn, B. A. (2024). Immunotherapeutic Potential of Mutated NPM1 for the Treatment of Acute Myeloid Leukemia. Cancers, 16(20), Article 3443. https://doi.org/10.3390/cancers16203443

Acute myeloid leukemia (AML) is a malignant disease of the blood and bone marrow that is characterized by uncontrolled clonal proliferation of abnormal myeloid progenitor cells. Nucleophosmin 1 (NPM1) gene mutations are the most common genetic abnorm... Read More about Immunotherapeutic Potential of Mutated NPM1 for the Treatment of Acute Myeloid Leukemia.

The environmental dependence of the stellar mass-gas metallicity relation in Horizon Run 5 (2024)
Journal Article
Rowntree, A., Singh, A., Vincenzo, F., Gibson, B. K., Gouin, C., Galárrag a-Espinosa, D., Lee, J., Kim, J., Laigle, C., Park, C., Pichon, C., Few, G., Hong, S. E., & Kim, Y. (2024). The environmental dependence of the stellar mass-gas metallicity relation in Horizon Run 5. Monthly notices of the Royal Astronomical Society, 531(4), 3858-3875. https://doi.org/10.1093/mnras/stae1384

Metallicity offers a unique window into the baryonic history of the cosmos, being instrumental in probing evolutionary processes in galaxies between different cosmic environments. We aim to quantify the contribution of these environments to the scatt... Read More about The environmental dependence of the stellar mass-gas metallicity relation in Horizon Run 5.

Can tumour antigens act as biomarkers for the early detection of non-small cell lung cancer? (2024)
Journal Article
Mohamed, E., Fletcher, D., Hart, S., & Guinn, B.-A. (2024). Can tumour antigens act as biomarkers for the early detection of non-small cell lung cancer?. Onco, 4(2), 87-100. https://doi.org/10.3390/onco4020008

Lung cancer (LC) is one of the leading causes of cancer-related deaths. Pulmonary nodules are one of the risk factors and their discovery rate has been increasing due to enhanced performance of chest CT scans but more than 90% are non-malignant causi... Read More about Can tumour antigens act as biomarkers for the early detection of non-small cell lung cancer?.

Analysis-on-a-roll platforms towards automated and high frequency in-situ sensing of natural geochemical fluxes (2024)
Thesis
Iurkov, A. Analysis-on-a-roll platforms towards automated and high frequency in-situ sensing of natural geochemical fluxes. (Thesis). University of Hull. https://hull-repository.worktribe.com/output/4702966

In the context of the rapidly intensifying crisis of climate change, the intricate dynamics of Earth's ecosystems have assumed a paramount significance. The carbon cycle plays a significant role in the dynamics of the earth’s ecosystem, and anthropog... Read More about Analysis-on-a-roll platforms towards automated and high frequency in-situ sensing of natural geochemical fluxes.

Identification of tumour anitgens that may facilitate effective cancer detection and treatment (2024)
Thesis
Mohamed, E. Identification of tumour anitgens that may facilitate effective cancer detection and treatment. (Thesis). University of Hull. https://hull-repository.worktribe.com/output/4866442

Tumour antigens (TAs) play a crucial role in terms of cancer diagnosis and targets for therapy. As TAs are normally expressed in restricted tissues such as testis, sensitivity and specificity may not be ideal, but they could still represent good biom... Read More about Identification of tumour anitgens that may facilitate effective cancer detection and treatment.

Identification of biomarkers for the early detection of non-small cell lung cancer: a systematic review and meta-analysis (2023)
Journal Article
Mohamed, E., García Martínez, D. J., Hosseini, M. S., Yoong, S. Q., Fletcher, D., Hart, S., & Guinn, B. A. (2024). Identification of biomarkers for the early detection of non-small cell lung cancer: a systematic review and meta-analysis. Carcinogenesis, 45(1-2), Article bgad091. https://doi.org/10.1093/carcin/bgad091

Lung cancer (LC) causes few symptoms in the earliest stages, leading to one of the highest mortality rates among cancers. Low-dose computerised tomography (LDCT) is used to screen high-risk individuals, reducing the mortality rate by 20%. However, LD... Read More about Identification of biomarkers for the early detection of non-small cell lung cancer: a systematic review and meta-analysis.

Mixtures of sediment chemical contaminants at freshwater sampling sites across Europe with different contaminant burdens (2023)
Journal Article
Richardson, S., Mayes, W. M., Faetsch, S., Hetjens, H., Teuchies, J., Walker, P., Heitmann, K., Welham, K., Moore, D., Bervoets, L., Kay, P., Duffus, W., Smith, N., De Cooman, W., Elst, R., Ryken, E., Rotchell, J. M., & Heise, S. (2023). Mixtures of sediment chemical contaminants at freshwater sampling sites across Europe with different contaminant burdens. Science of the Total Environment, 891, Article 164280. https://doi.org/10.1016/j.scitotenv.2023.164280

Extended chemical analyses of fluvial sediments were undertaken to establish the key pollutant pressures and mixtures present across nine European Union inland waterways. A wide range of chemical components and physical parameters were investigated i... Read More about Mixtures of sediment chemical contaminants at freshwater sampling sites across Europe with different contaminant burdens.