Outputs (2)

Adult B-Cell Acute Lymphoblastic Leukaemia Antigens and Enriched Pathways Identify New Targets for Therapy (2025)
Journal Article
Mohamed, E., Goodman, S., Cooksey, L., Fletcher, D. M., Dean, O., Boncheva, V. B., Mills, K. I., Orchard, K. H., & Guinn, B.-A. (2025). Adult B-Cell Acute Lymphoblastic Leukaemia Antigens and Enriched Pathways Identify New Targets for Therapy. Onco, 5(2), Article 19. https://doi.org/10.3390/onco5020019

Background: Adult B-cell acute lymphoblastic leukaemia (aB-ALL) is charac-terised by abnormal differentiation and proliferation of lymphoid progenitors. Despite a significant improvement in relapse-free and overall survival for children with BALL , a... Read More about Adult B-Cell Acute Lymphoblastic Leukaemia Antigens and Enriched Pathways Identify New Targets for Therapy.

Dynamic co-evolution of transposable elements and the piRNA pathway in African cichlid fishes (2025)
Journal Article
Almeida, M. V., Blumer, M., Yuan, C. U., Sierra, P., Price, J. L., Quah, F. X., Friman, A., Dallaire, A., Vernaz, G., Putman, A. L., Smith, A. M., Joyce, D. A., Butter, F., Haase, A. D., Durbin, R., Santos, M. E., & Miska, E. A. (2025). Dynamic co-evolution of transposable elements and the piRNA pathway in African cichlid fishes. Genome Biology, 26(1), Article 14. https://doi.org/10.1186/s13059-025-03475-z

BACKGROUND: East African cichlid fishes have diversified in an explosive fashion, but the (epi)genetic basis of the phenotypic diversity of these fishes remains largely unknown. Although transposable elements (TEs) have been associated with phenotypi... Read More about Dynamic co-evolution of transposable elements and the piRNA pathway in African cichlid fishes.