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Outputs (173)

Optimising a person-centred approach to stopping medicines in older people with multimorbidity and polypharmacy using the DExTruS framework: a realist review (2022)
Journal Article
Turk, A., Wong, G., Mahtani, K. R., Madden, M., Hill, R., Ranson, E., Wallace, E., Krska, J., Mangin, D., Byng, R., Lasserson, D., & Reeve, J. (2022). Optimising a person-centred approach to stopping medicines in older people with multimorbidity and polypharmacy using the DExTruS framework: a realist review. BMC medicine, 20(1), Article 297. https://doi.org/10.1186/s12916-022-02475-1

BACKGROUND: Tackling problematic polypharmacy requires tailoring the use of medicines to individual circumstances and may involve the process of deprescribing. Deprescribing can cause anxiety and concern for clinicians and patients. Tailoring medicat... Read More about Optimising a person-centred approach to stopping medicines in older people with multimorbidity and polypharmacy using the DExTruS framework: a realist review.

Mixed-methods feasibility cluster randomised controlled trial of a paramedic-administered breathlessness management intervention for acute-on-chronic breathlessness (BREATHE): study findings (2022)
Journal Article
Hutchinson, A., Allgar, V., Cohen, J., Currow, D. C., Griffin, S., Hart, S., Hird, K., Hodge, A., Mason, S., Northgraves, M., Reeve, J., Swan, F., & Johnson, M. J. (2022). Mixed-methods feasibility cluster randomised controlled trial of a paramedic-administered breathlessness management intervention for acute-on-chronic breathlessness (BREATHE): study findings. ERJ Open Research, 8(4), Article 00257-2022. https://doi.org/10.1183/23120541.00257-2022

Introduction: One-fifth of emergency department presentations by ambulance are due to acute-on-chronic breathlessness. We explored the feasibility of an evaluation-phase, cluster randomised controlled trial (cRCT) of the effectiveness and cost-effect... Read More about Mixed-methods feasibility cluster randomised controlled trial of a paramedic-administered breathlessness management intervention for acute-on-chronic breathlessness (BREATHE): study findings.

Report: Deprescribing medicines in older people living with multimorbidity and polypharmacy: the TAILOR evidence synthesis (2022)
Journal Article
Reeve, J., Maden, M., Hill, R., Turk, A., Mahtani, K., Wong, G., Lasserson, D., Krska, J., Mangin, D., Byng, R., Wallace, E., & Ranson, E. (2022). Report: Deprescribing medicines in older people living with multimorbidity and polypharmacy: the TAILOR evidence synthesis. Health Technology Assessment, 26(32), VII-108. https://doi.org/10.3310/AAFO2475

Background: Tackling problematic polypharmacy requires tailoring the use of medicines to individual needs and circumstances. This may involve stopping medicines (deprescribing) but patients and clinicians report uncertainty on how best to do this. Th... Read More about Report: Deprescribing medicines in older people living with multimorbidity and polypharmacy: the TAILOR evidence synthesis.

Feasibility and effectiveness of deprescribing benzodiazepines and Z-drugs; systematic review and meta-analysis (2022)
Journal Article
Soni, A., Thiyagarajan, A., & Reeve, J. (2022). Feasibility and effectiveness of deprescribing benzodiazepines and Z-drugs; systematic review and meta-analysis. Addiction, https://doi.org/10.1111/add.15997

Background and Aims
2.4 million adults in England were dispensed a benzodiazepine or Z-drug (BZRA) in 2017/18, and more than 250,000 patients in the UK take BZRAs beyond the recommended duration. Deprescribing is a clinician-guided process of withdr... Read More about Feasibility and effectiveness of deprescribing benzodiazepines and Z-drugs; systematic review and meta-analysis.

Translating qualitative data into intervention content using the Theoretical Domains Framework and stakeholder co-design: a worked example from a study of cervical screening attendance in older women (2022)
Journal Article
Bravington, A., Chen, H., Dyson, J., Jones, L., Dalgliesh, C., Bryan, A., Patnick, J., & Macleod, U. (2022). Translating qualitative data into intervention content using the Theoretical Domains Framework and stakeholder co-design: a worked example from a study of cervical screening attendance in older women. BMC health services research, 22(1), Article 610. https://doi.org/10.1186/s12913-022-07926-2

Background: Previous screening interventions have demonstrated a series of features related to social determinants which have increased uptake in targeted populations, including the assessment of health beliefs and barriers to screening attendance as... Read More about Translating qualitative data into intervention content using the Theoretical Domains Framework and stakeholder co-design: a worked example from a study of cervical screening attendance in older women.

A qualitative exploration of women's perspectives and acceptability of including new cancer awareness information in all‐clear breast or cervical screening results (2022)
Journal Article
Bamidele, O. O., Green, T., Tookey, S., Walabyeki, J., & Macleod, U. (2022). A qualitative exploration of women's perspectives and acceptability of including new cancer awareness information in all‐clear breast or cervical screening results. European Journal of Cancer Care, https://doi.org/10.1111/ecc.13574

Objective: This study explored women's perspectives on the acceptability of including new cancer information with an all-clear breast or cervical screening result letter (using ovarian cancer as a case study). Methods: In 2016, six focus group discus... Read More about A qualitative exploration of women's perspectives and acceptability of including new cancer awareness information in all‐clear breast or cervical screening results.

An evaluation of community placements for GP registrars in Yorkshire and the Humber: ‘a home visit… not to a patient but to the community’ (2022)
Journal Article
Lang, J., Graffy, H., & Reeve, J. (in press). An evaluation of community placements for GP registrars in Yorkshire and the Humber: ‘a home visit… not to a patient but to the community’. Education for Primary Care, https://doi.org/10.1080/14739879.2022.2027274

Background: GP registrars are required to demonstrate capabilities in ‘community orientation’, reflecting skills in developing and working with services that respond to community needs. These skills have sometimes been seen as vague and difficult to... Read More about An evaluation of community placements for GP registrars in Yorkshire and the Humber: ‘a home visit… not to a patient but to the community’.

Geographical distance and reduced access to palliative radiotherapy: Systematic review and meta-analysis (2022)
Journal Article
Chand, C. P., Greenley, S., Macleod, U., Lind, M., Barton, R., & Kelly, C. (2022). Geographical distance and reduced access to palliative radiotherapy: Systematic review and meta-analysis. BMJ supportive & palliative care, https://doi.org/10.1136/bmjspcare-2021-003356

Background: Palliative radiotherapy (PRT) is an effective way of reducing symptoms caused by advanced incurable cancer. Several studies have investigated factors that contribute to inequalities in access to PRT; distance to a radiotherapy centre has... Read More about Geographical distance and reduced access to palliative radiotherapy: Systematic review and meta-analysis.