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Outputs (168)

Yorkshire Lung Screening Trial (YLST): protocol for a randomised controlled trial to evaluate invitation to community-based low-dose CT screening for lung cancer versus usual care in a targeted population at risk (2020)
Journal Article
Crosbie, P. A., Gabe, R., Simmonds, I., Kennedy, M., Rogerson, S., Ahmed, N., Baldwin, D. R., Booton, R., Cochrane, A., Darby, M., Franks, K., Hinde, S., Janes, S. M., Macleod, U., Messenger, M., Moller, H., Murray, R. L., Neal, R. D., Quaife, S. L., Sculpher, M., …Callister, M. E. (2020). Yorkshire Lung Screening Trial (YLST): protocol for a randomised controlled trial to evaluate invitation to community-based low-dose CT screening for lung cancer versus usual care in a targeted population at risk. BMJ open, 10(9), Article e037075. https://doi.org/10.1136/bmjopen-2020-037075

© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY. Published by BMJ. INTRODUCTION: Lung cancer is the world's leading cause of cancer death. Low-dose computed tomography (LDCT) screening reduced lung cancer mortality by 20% in the... Read More about Yorkshire Lung Screening Trial (YLST): protocol for a randomised controlled trial to evaluate invitation to community-based low-dose CT screening for lung cancer versus usual care in a targeted population at risk.

Avoiding harm: Tackling problematic polypharmacy through strengthening expert generalist practice (2020)
Journal Article
Reeve, J. (in press). Avoiding harm: Tackling problematic polypharmacy through strengthening expert generalist practice. British Journal of Clinical Pharmacology, https://doi.org/10.1111/bcp.14531

Problematic polypharmacy is a growing challenge. Medication that is intended to improve patients' health and wellbeing is instead becoming part of the problem. The way we practice medicine has become a driver for the problem. Dealing with the challen... Read More about Avoiding harm: Tackling problematic polypharmacy through strengthening expert generalist practice.

Surgical Treatment for Recurrent Bulbar Urethral Stricture: A Randomised Open-label Superiority Trial of Open Urethroplasty Versus Endoscopic Urethrotomy (the OPEN Trial) (2020)
Journal Article
Goulao, B., Carnell, S., Shen, J., MacLennan, G., Norrie, J., Cook, J., …Pickard, R. (2020). Surgical Treatment for Recurrent Bulbar Urethral Stricture: A Randomised Open-label Superiority Trial of Open Urethroplasty Versus Endoscopic Urethrotomy (the OPEN Trial). European Urology, 78(4), 572-580. https://doi.org/10.1016/j.eururo.2020.06.003

Background
Urethral stricture affects 0.9% of men. Initial treatment is urethrotomy. Approximately, half of the strictures recur within 4 yr. Options for further treatment are repeat urethrotomy or open urethroplasty.
Objective
To compare the effe... Read More about Surgical Treatment for Recurrent Bulbar Urethral Stricture: A Randomised Open-label Superiority Trial of Open Urethroplasty Versus Endoscopic Urethrotomy (the OPEN Trial).

REDUCE (Reviewing long-term antidepressant use by careful monitoring in everyday practice) internet and telephone support to people coming off long-term antidepressants: Protocol for a randomised controlled trial (2020)
Journal Article
Kendrick, T., Geraghty, A. W., Bowers, H., Stuart, B., Leydon, G., May, C., Yao, G., O'Brien, W., Glowacka, M., Holley, S., Williams, S., Zhu, S., Dewar-Haggart, R., Palmer, B., Bell, M., Collinson, S., Fry, I., Lewis, G., Griffiths, G., Gilbody, S., …Dowrick, C. (2020). REDUCE (Reviewing long-term antidepressant use by careful monitoring in everyday practice) internet and telephone support to people coming off long-term antidepressants: Protocol for a randomised controlled trial. Trials, 21(1), Article 419. https://doi.org/10.1186/s13063-020-04338-7

© 2020 The Author(s). Background: Around one in ten adults take antidepressants for depression in England, and their long-term use is increasing. Some need them to prevent relapse, but 30-50% could possibly stop them without relapsing and avoid adver... Read More about REDUCE (Reviewing long-term antidepressant use by careful monitoring in everyday practice) internet and telephone support to people coming off long-term antidepressants: Protocol for a randomised controlled trial.

Supporting social prescribing in primary care by linking people to local assets: A realist review (2020)
Journal Article
Tierney, S., Wong, G., Roberts, N., Boylan, A. M., Park, S., Abrams, R., Reeve, J., Williams, V., & Mahtani, K. R. (2020). Supporting social prescribing in primary care by linking people to local assets: A realist review. BMC medicine, 18(1), Article 49. https://doi.org/10.1186/s12916-020-1510-7

© 2020 The Author(s). Background: Social prescribing is a way of addressing the 'non-medical' needs (e.g. loneliness, debt, housing problems) that can affect people's health and well-being. Connector schemes (e.g. delivered by care navigators or link... Read More about Supporting social prescribing in primary care by linking people to local assets: A realist review.

'Unpacking' pathways to lymphoma and myeloma diagnosis: Do experiences align with the Model of Pathways to Treatment? Findings from a UK qualitative study with patients and relatives (2020)
Journal Article
Howell, D., Hart, R., Smith, A., MacLeod, U., Patmore, R., & Roman, E. (2020). 'Unpacking' pathways to lymphoma and myeloma diagnosis: Do experiences align with the Model of Pathways to Treatment? Findings from a UK qualitative study with patients and relatives. BMJ open, 10(2), Article e034244. https://doi.org/10.1136/bmjopen-2019-034244

© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY. Published by BMJ. Objectives To explore alignment of experiences before lymphoma and myeloma diagnosis with the appraisal, help seeking and diagnostic intervals in the Model of Pa... Read More about 'Unpacking' pathways to lymphoma and myeloma diagnosis: Do experiences align with the Model of Pathways to Treatment? Findings from a UK qualitative study with patients and relatives.

Palliative care for non-cancer conditions in primary care: a time trend analysis in the UK (2009–2014) (2020)
Journal Article
Gadoud, A., Kane, E., Oliver, S. E., Johnson, M. J., MacLeod, U., & Allgar, V. (2020). Palliative care for non-cancer conditions in primary care: a time trend analysis in the UK (2009–2014). BMJ supportive & palliative care, Article 001833. https://doi.org/10.1136/bmjspcare-2019-001833

Objectives While guidelines recommend palliative care in non-cancer conditions, this has not been widely implemented. We examined whether the recording of a palliative care approach and the numbers of hospital deaths for deceased patients with heart... Read More about Palliative care for non-cancer conditions in primary care: a time trend analysis in the UK (2009–2014).

What do the healthcare experiences of people with long-term conditions tell us about person-centred care? A systematic review. (2019)
Journal Article
Dell Olio, M., Pask, S., Seymour, J., & Reeve, J. (2019). What do the healthcare experiences of people with long-term conditions tell us about person-centred care? A systematic review. European journal for person centered healthcare, 7(4),

Introduction
Growing numbers of people now live with long term conditions. For each person, the challenges are multiple and unique to that individual. In recognition of this, health policy places greater emphasis on the delivery of person-centred ca... Read More about What do the healthcare experiences of people with long-term conditions tell us about person-centred care? A systematic review..

Non-attendance at urgent referral appointments for suspected cancer: A qualitative study to gain understanding from patients and GPS (2019)
Journal Article
Jefferson, L., Atkin, K., Sheridan, R., Oliver, S., Macleod, U., Hall, G., Forbes, S., Green, T., Allgar, V., & Knapp, P. (2019). Non-attendance at urgent referral appointments for suspected cancer: A qualitative study to gain understanding from patients and GPS. The British journal of general practice : the journal of the Royal College of General Practitioners, 69(689), E850-E859. https://doi.org/10.3399/bjgp19X706625

© British Journal of General Practice
Background: The 2-week-wait urgent referral policy in the UK has sought to improve cancer outcomes by accelerating diagnosis and treatment. However, around 5-7% of symptomatic referred patients cancel or do not... Read More about Non-attendance at urgent referral appointments for suspected cancer: A qualitative study to gain understanding from patients and GPS.