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Outputs (65)

Implementation of the Cognitive Daisy (COG-D) for improving care planning and delivery for residents with dementia in care homes: results of a feasibility randomised controlled trial (2025)
Journal Article
Pollux, P. M., Surr, C., Cohen, J., Huang, C., Wolverson, E., Mountain, P., Clarke, R., Hawkesford-Webb, E., Winter, B., & Hudson, J. M. (2025). Implementation of the Cognitive Daisy (COG-D) for improving care planning and delivery for residents with dementia in care homes: results of a feasibility randomised controlled trial. Pilot and Feasibility Studies, 11, Article 66. https://doi.org/10.1186/s40814-025-01637-1

Background: Many residents in care homes for older adults live with dementia. Understanding the unique profiles of cognitive impairments for each resident is important for person-centred care, yet information about specific cognitive problems is limi... Read More about Implementation of the Cognitive Daisy (COG-D) for improving care planning and delivery for residents with dementia in care homes: results of a feasibility randomised controlled trial.

Effectiveness of biomarker-guided duration of antibiotic treatment in children hospitalised with confirmed or suspected bacterial infection: the BATCH RCT (2025)
Journal Article
Waldron, C. A., Pallmann, P., Schoenbuchner, S., Harris, D., Brookes-Howell, L., Mateus, C., Bernatoniene, J., Cathie, K., Faust, S. N., Henley, J., Hinds, L., Hood, K., Huang, C., Jones, S., Kotecha, S., Milosevic, S., Nabwera, H., Patel, S., Paulus, S., Powell, C. V., …Carrol, E. D. (2025). Effectiveness of biomarker-guided duration of antibiotic treatment in children hospitalised with confirmed or suspected bacterial infection: the BATCH RCT. Health Technology Assessment, 29(16), 1-125. https://doi.org/10.3310/MBVA3675

Background: Procalcitonin is a biomarker specific for bacterial infection, with a more rapid response than other commonly used biomarkers, such as C-reactive protein, but it is not routinely used in the National Health Service. Objective: To determin... Read More about Effectiveness of biomarker-guided duration of antibiotic treatment in children hospitalised with confirmed or suspected bacterial infection: the BATCH RCT.

Complex breathlessness intervention in idiopathic pulmonary fibrosis (BREEZE-IPF): a feasibility, wait-list design randomised controlled trial (2025)
Journal Article
Crooks, M. G., Wright, C., Hart, S., Allgar, V., English, A., Swan, F., Dyson, J., Richardson, G., Twiddy, M., Cohen, J., Simpson, A., Huang, C., Sykes, D. L., & Johnson, M. (2025). Complex breathlessness intervention in idiopathic pulmonary fibrosis (BREEZE-IPF): a feasibility, wait-list design randomised controlled trial. BMJ Open Respiratory Research, 12(1), Article e002327. https://doi.org/10.1136/bmjresp-2024-002327

Introduction Breathlessness is common and impairs the quality of life of people with idiopathic pulmonary fibrosis (IPF) and non-IPF fibrotic interstitial lung diseases (ILD). We report the findings of a multicentre, fast-track (wait-list), mixed-met... Read More about Complex breathlessness intervention in idiopathic pulmonary fibrosis (BREEZE-IPF): a feasibility, wait-list design randomised controlled trial.

Identifying haemochromatosis patients with C282Y homozygosity from inpatient electronic patient records in England using a novel algorithm: a retrospective observational study (2025)
Journal Article
Singh, P., Millson, C., Huang, C., & Driver, R. J. (2025). Identifying haemochromatosis patients with C282Y homozygosity from inpatient electronic patient records in England using a novel algorithm: a retrospective observational study. BMJ open, 15(2), Article e089369. https://doi.org/10.1136/bmjopen-2024-089369

INTRODUCTION: Hereditary haemochromatosis (HH) is the most common genetic condition among populations of northern European ancestry, but it does not have a specific International Classification of Diseases 10th revision (ICD-10) diagnosis code. HH is... Read More about Identifying haemochromatosis patients with C282Y homozygosity from inpatient electronic patient records in England using a novel algorithm: a retrospective observational study.

Procalcitonin-guided duration of antibiotic treatment in children hospitalised with confirmed or suspected bacterial infection in the UK (BATCH): a pragmatic, multicentre, open-label, two-arm, individually randomised, controlled trial (2025)
Journal Article
Waldron, C. A., Pallmann, P., Schoenbuchner, S., Harris, D., Brookes-Howell, L., Mateus, C., Bernatoniene, J., Cathie, K., Faust, S. N., Hinds, L., Hood, K., Huang, C., Jones, S., Kotecha, S., Nabwera, H. M., Patel, S., Paulus, S. C., Powell, C. V. E., Preston, J., Xiang, H., …on behalf of the BATCH Trial Team. (2025). Procalcitonin-guided duration of antibiotic treatment in children hospitalised with confirmed or suspected bacterial infection in the UK (BATCH): a pragmatic, multicentre, open-label, two-arm, individually randomised, controlled trial. The Lancet Child & Adolescent Health, 9(2), 121-130. https://doi.org/10.1016/S2352-4642%2824%2900306-7

Background: Procalcitonin is a rapid response biomarker specific for bacterial infection, which is not routinely used in the UK National Health Service. We aimed to assess whether using a procalcitonin-guided algorithm would safely reduce the duratio... Read More about Procalcitonin-guided duration of antibiotic treatment in children hospitalised with confirmed or suspected bacterial infection in the UK (BATCH): a pragmatic, multicentre, open-label, two-arm, individually randomised, controlled trial.

The relationship between muscle mass changes and protein or energy intake in critically ill children: A systematic review and meta-analysis (2024)
Journal Article
Stacey, L. J., Valla, F. V., Huang, C., Comfort, P., Chaparro, C. J., Latten, L., & Tume, L. N. (in press). The relationship between muscle mass changes and protein or energy intake in critically ill children: A systematic review and meta-analysis. Journal of Parenteral and Enteral Nutrition, https://doi.org/10.1002/jpen.2715

Survivorship after pediatric critical illness is high in developed countries, but many suffer physical morbidities afterwards. The increasing focus on follow-up after critical illness has led to more pediatric studies reporting muscle mass changes (u... Read More about The relationship between muscle mass changes and protein or energy intake in critically ill children: A systematic review and meta-analysis.

Home-based high intensity interval training in patients with intermittent claudication: a systematic review protocol (2024)
Journal Article
Prosser, J., Staniland, T., Harwood, A., Ravindhran, B., McGregor, G., Huang, C., Twiddy, M., Nicholls, A., Ingle, L., Long, J., Chetter, I., & Pymer, S. (2024). Home-based high intensity interval training in patients with intermittent claudication: a systematic review protocol. Journal of Vascular Societies Great Britain and Ireland, 3(3), 155-159. https://doi.org/10.54522/jvsgbi.2024.103

Introduction: The aim of this systematic review is to consider the evidence base for home-based high intensity interval training (HIIT) in patients with intermittent claudication (IC). Prior knowledge of the evidence base suggests that there may be l... Read More about Home-based high intensity interval training in patients with intermittent claudication: a systematic review protocol.

High INtensity Interval Training in pATiEnts with Intermittent Claudication: A Qualitative Acceptability Study (2024)
Journal Article
Pymer, S., Harwood, A., Ibeggazene, S., McGregor, G., Huang, C., Nicholls, A., Ingle, L., Long, J., Rooms, M., Chetter, I. C., & Twiddy, M. (2024). High INtensity Interval Training in pATiEnts with Intermittent Claudication: A Qualitative Acceptability Study. Annals of vascular surgery, 102, 17-24. https://doi.org/10.1016/j.avsg.2023.11.043

Background: A novel high-intensity interval training (HIIT) program has demonstrated feasibility for patients with intermittent claudication (IC). The aim of this study was to explore patient perspectives of the HIIT program to inform refinement and... Read More about High INtensity Interval Training in pATiEnts with Intermittent Claudication: A Qualitative Acceptability Study.

High-intensity interval training in patients with intermittent claudication (2023)
Presentation / Conference Contribution
Pymer, S., Harwood, A. E., Prosser, J., Waddell, A., Rhavindhran, B., McGregor, G., Ibeggazene, S., Huang, C., Twiddy, M., Nicholls, A. R., Ingle, L., Carroll, S., He, H., Long, J., Rooms, M., & Chetter, I. C. High-intensity interval training in patients with intermittent claudication. Presented at 2022 Vascular Society of Great Britain and Ireland Annual Scientific Meeting, Brighton, UK

Objective: Provision, uptake, adherence, and completion rates for supervised exercise programs (SEP) for intermittent claudication (IC) are low. A shorter, more time-efficient, 6-week, high-intensity interval training (HIIT) program may be an effecti... Read More about High-intensity interval training in patients with intermittent claudication.