Skip to main content

Research Repository

Advanced Search

Outputs (72)

Breathlessness without borders: a call to action for global breathlessness research (2024)
Journal Article
Clark, J. D., Binnie, K., Bond, M., Crooks, M., Currow, D. C., Curry, J., Elsey, H., Habib, M., Hutchinson, A., Soyiri, I., Johnson, M. J., Nair, S., Rao, S., Siqueira-Filha, N., Spathis, A., & Williams, S. (2024). Breathlessness without borders: a call to action for global breathlessness research. NPJ Primary Care Respiratory Medicine, 34(1), Article 26. https://doi.org/10.1038/s41533-024-00384-9

It is likely that the burden of breathlessness in low and middle-income countries (LMICs) is much higher than has been estimated using calculations of disease burden and expected prevalence of the symptom. However, most breathlessness research has be... Read More about Breathlessness without borders: a call to action for global breathlessness research.

The state of health in the European Union (EU-27) in 2019: a systematic analysis for the Global Burden of Disease study 2019 (2024)
Journal Article
Santos, J. V., Padron-Monedero, A., Bikbov, B., Grad, D. A., Plass, D., Mechili, E. A., Gazzelloni, F., Fischer, F., Sulo, G., Ngwa, C. H., Noguer-Zambrano, I., Peñalvo, J. L., Haagsma, J. A., Kissimova-Skarbek, K., Monasta, L., Ghith, N., Sarmiento-Suárez, R., Hrzic, R., Haneef, R., O'caoimh, R., …Soyiri, I. N. (2024). The state of health in the European Union (EU-27) in 2019: a systematic analysis for the Global Burden of Disease study 2019. BMC public health, 24(1), Article 1374. https://doi.org/10.1186/s12889-024-18529-3

Background: The European Union (EU) faces many health-related challenges. Burden of diseases information and the resulting trends over time are essential for health planning. This paper reports estimates of disease burden in the EU and individual 27... Read More about The state of health in the European Union (EU-27) in 2019: a systematic analysis for the Global Burden of Disease study 2019.

Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 (2024)
Journal Article
Brauer, M., Roth, G. A., & Soyiri, I. (2024). Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021. Lancet, 403(10440), 2162-2203. https://doi.org/10.1016/S0140-6736%2824%2900933-4

Background: Understanding the health consequences associated with exposure to risk factors is necessary to inform public health policy and practice. To systematically quantify the contributions of risk factor exposures to specific health outcomes, th... Read More about Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021.

Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950–2021, and the impact of the COVID-19 pandemic: a comprehensive demographic analysis for the Global Burden of Disease Study 2021 (2024)
Journal Article
Schumacher, A. E., Hmwe Kyu, H., & Soyiri, I. N. (2024). Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950–2021, and the impact of the COVID-19 pandemic: a comprehensive demographic analysis for the Global Burden of Disease Study 2021. Lancet, 403(10440), 1989-2056. https://doi.org/10.1016/S0140-6736%2824%2900476-8

Background: Estimates of demographic metrics are crucial to assess levels and trends of population health outcomes. The profound impact of the COVID-19 pandemic on populations worldwide has underscored the need for timely estimates to understand this... Read More about Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950–2021, and the impact of the COVID-19 pandemic: a comprehensive demographic analysis for the Global Burden of Disease Study 2021.

Outcomes in patients treated with loop diuretics without a diagnosis of heart failure: a retrospective cohort study (2024)
Journal Article
Cuthbert, J. J., Soyiri, I., Lomax, S. J., Turgoose, J., Fuat, A., Cohen, J., & Clark, A. L. (2024). Outcomes in patients treated with loop diuretics without a diagnosis of heart failure: a retrospective cohort study. Heart, 110(12), 854-862. https://doi.org/10.1136/heartjnl-2023-323577

Background Loop diuretics are commonly prescribed in the community, not always to patients with a recorded diagnosis of heart failure (HF). The rate of HF events in patients prescribed loop diuretics without a diagnosis of HF is unknown. Methods This... Read More about Outcomes in patients treated with loop diuretics without a diagnosis of heart failure: a retrospective cohort study.

Breathlessness limiting exertion in very old adults: findings from the Newcastle 85+ study (2023)
Journal Article
Johnson, M. J., Pitel, L., Currow, D. C., Forbes, C., Soyiri, I., & Robinson, L. (2023). Breathlessness limiting exertion in very old adults: findings from the Newcastle 85+ study. Age and ageing, 52(9), Article afad155. https://doi.org/10.1093/ageing/afad155

INTRODUCTION: Long-term breathlessness is more common with age. However, in the oldest old (>85years), little is known about the prevalence, or impact of breathlessness. We estimated breathlessness limiting exertion prevalence and explored (i) associ... Read More about Breathlessness limiting exertion in very old adults: findings from the Newcastle 85+ study.

Mapping development and health effects of cooking with solid fuels in low-income and middle-income countries, 2000–18: a geospatial modelling study (2022)
Journal Article
Frostad, J. J., Nguyen, Q. A. P., Baumann, M. M., Blacker, B. F., Marczak, L. B., Deshpande, A., Wiens, K. E., LeGrand, K. E., Johnson, K. B., Abbasi-Kangevari, M., Abdoli, A., Abolhassani, H., Abreu, L. G., Abrigo, M. R., Abu-Rmeileh, N. M., Adekanmbi, V., Agrawal, A., Ahmed, M. B., Al-Aly, Z., Alanezi, F. M., …Soyiri, I. (2022). Mapping development and health effects of cooking with solid fuels in low-income and middle-income countries, 2000–18: a geospatial modelling study. The Lancet global health, 10(10), e1395-e1411. https://doi.org/10.1016/S2214-109X%2822%2900332-1

Background: More than 3 billion people do not have access to clean energy and primarily use solid fuels to cook. Use of solid fuels generates household air pollution, which was associated with more than 2 million deaths in 2019. Although local patter... Read More about Mapping development and health effects of cooking with solid fuels in low-income and middle-income countries, 2000–18: a geospatial modelling study.

Estimates, trends, and drivers of the global burden of type 2 diabetes attributable to PM2·5 air pollution, 1990–2019: an analysis of data from the Global Burden of Disease Study 2019 (2022)
Journal Article
Burkart, K., Causey, K., Cohen, A. J., Wozniak, S. S., Salvi, D. D., Abbafati, C., Adekanmbi, V., Adsuar, J. C., Ahmadi, K., Alahdab, F., Al-Aly, Z., Alipour, V., Alvis-Guzman, N., Amegah, A. K., Andrei, C. L., Andrei, T., Ansari, F., Arabloo, J., Aremu, O., Aripov, T., …Soyiri, I. (2022). Estimates, trends, and drivers of the global burden of type 2 diabetes attributable to PM2·5 air pollution, 1990–2019: an analysis of data from the Global Burden of Disease Study 2019. The Lancet Planetary Health, 6(7), e586-e600. https://doi.org/10.1016/S2542-5196%2822%2900122-X

Background: Experimental and epidemiological studies indicate an association between exposure to particulate matter (PM) air pollution and increased risk of type 2 diabetes. In view of the high and increasing prevalence of diabetes, we aimed to quant... Read More about Estimates, trends, and drivers of the global burden of type 2 diabetes attributable to PM2·5 air pollution, 1990–2019: an analysis of data from the Global Burden of Disease Study 2019.

Mapping routine measles vaccination in low- and middle-income countries (2020)
Journal Article
Local Burden of Disease Vaccine Coverage Collaborators, & Soyiri, I. (2021). Mapping routine measles vaccination in low- and middle-income countries. Nature, 589, 415-419. https://doi.org/10.1038/s41586-020-03043-4

The safe, highly effective measles vaccine has been recommended globally since 1974, yet in 2017 there were more than 17 million cases of measles and 83,400 deaths in children under 5 years old, and more than 99% of both occurred in low- and middle-i... Read More about Mapping routine measles vaccination in low- and middle-income countries.

Hormone replacement therapy and asthma onset in menopausal women: National cohort study (2020)
Journal Article
Shah, S. A., Tibble, H., Pillinger, R., McLean, S., Ryan, D., Critchley, H., Price, D., Hawrylowicz, C. M., Simpson, C. R., Soyiri, I. N., Appiagyei, F., Sheikh, A., & Nwaru, B. I. (2020). Hormone replacement therapy and asthma onset in menopausal women: National cohort study. Journal of Allergy and Clinical Immunology, https://doi.org/10.1016/j.jaci.2020.11.024

© 2020 The Authors
Background: There is uncertainty about the role of hormonal replacement therapy (HRT) in the development of asthma.
Objective: We investigated whether use of HRT and duration of use was associated with risk of development of as... Read More about Hormone replacement therapy and asthma onset in menopausal women: National cohort study.