Outputs (14)

High risk (B3) breast lesions: What is the incidence of malignancy for individual lesion subtypes? A systematic review and meta-analysis (2018)
Journal Article
Forester, N. D., Lowes, S., Mitchell, E., & Twiddy, M. (2019). High risk (B3) breast lesions: What is the incidence of malignancy for individual lesion subtypes? A systematic review and meta-analysis. European journal of surgical oncology, 45(4), 519-527. https://doi.org/10.1016/j.ejso.2018.12.008

© 2018 Introduction: Provide evidence to support evolving management strategies for high-risk (B3) breast lesions by assessing risk of carcinoma in subgroups of B3 lesions using systematic review and meta-analysis. Methods: Databases identified obser... Read More about High risk (B3) breast lesions: What is the incidence of malignancy for individual lesion subtypes? A systematic review and meta-analysis.

The future for diagnostic tests of acute kidney injury in critical care: evidence synthesis, care pathway analysis and research prioritisation (2018)
Journal Article
Hall, P. S., Mitchell, E. D., Smith, A. F., Cairns, D. A., Messenger, M., Hutchinson, M., Wright, J., Vinall-Collier, K., Corps, C., Hamilton, P., Meads, D., & Lewington, A. (2018). The future for diagnostic tests of acute kidney injury in critical care: evidence synthesis, care pathway analysis and research prioritisation. Health Technology Assessment, 22(32), 1-274. https://doi.org/10.3310/hta22320

© Queen’s Printer and Controller of HMSO 2018. Background: Acute kidney injury (AKI) is highly prevalent in hospital inpatient populations, leading to significant mortality and morbidity, reduced quality of life and high short- and long-term health-c... Read More about The future for diagnostic tests of acute kidney injury in critical care: evidence synthesis, care pathway analysis and research prioritisation.

A qualitative study of patients’ feedback about Outpatient Parenteral Antimicrobial Therapy (OPAT) services in Northern England : implications for service improvement (2018)
Journal Article
Twiddy, M., Czoski Murray, C. J., Mason, S. J., Meads, D., Wright, J. M., Mitchell, E. D., & Minton, J. (2018). A qualitative study of patients’ feedback about Outpatient Parenteral Antimicrobial Therapy (OPAT) services in Northern England : implications for service improvement. BMJ open, 8(1), e019099. https://doi.org/10.1136/bmjopen-2017-019099

Abstract
Objective Outpatient parenteral antimicrobial therapy (OPAT) provides opportunities for improved cost savings, but in the UK, implementation is patchy and a variety of service models are in use. The slow uptake in the UK and Europe is due to... Read More about A qualitative study of patients’ feedback about Outpatient Parenteral Antimicrobial Therapy (OPAT) services in Northern England : implications for service improvement.

Clinical and cost-effectiveness, safety and acceptability of community intravenous antibiotic service models: CIVAS systematic review (2017)
Journal Article
Murray, C. C., Mitchell, E. D., Czoski Murray, C., Meads, D., Minton, J., Wright, J., & Twiddy, M. (2017). Clinical and cost-effectiveness, safety and acceptability of community intravenous antibiotic service models: CIVAS systematic review. BMJ open, 7(4), Article e013560. https://doi.org/10.1136/bmjopen-2016-013560

OBJECTIVE:
Evaluate evidence of the efficacy, safety, acceptability and cost-effectiveness of outpatient parenteral antimicrobial therapy (OPAT) models.
DESIGN:
A systematic review.
DATA SOURCES:
MEDLINE, EMBASE, CINAHL, Cochrane Library, National He... Read More about Clinical and cost-effectiveness, safety and acceptability of community intravenous antibiotic service models: CIVAS systematic review.

The Community IntraVenous Antibiotic Study (CIVAS): a mixed-methods evaluation of patient preferences for and cost-effectiveness of different service models for delivering outpatient parenteral antimicrobial therapy (2017)
Journal Article
Minton, J., Murray, C. C., Meads, D., Hess, S., Vargas-Palacios, A., Mitchell, E., Wright, J., Hulme, C., Raynor, D. K., Gregson, A., Stanley, P., McLintock, K., Vincent, R., & Twiddy, M. (2017). The Community IntraVenous Antibiotic Study (CIVAS): a mixed-methods evaluation of patient preferences for and cost-effectiveness of different service models for delivering outpatient parenteral antimicrobial therapy. Health Services and Delivery Research, 5(6), 1-272. https://doi.org/10.3310/hsdr05060

Background

Outpatient parenteral antimicrobial therapy (OPAT) is widely used in most developed countries, providing considerable opportunities for improved cost savings. However, it is implemented only partially in the UK, using a variety of servi... Read More about The Community IntraVenous Antibiotic Study (CIVAS): a mixed-methods evaluation of patient preferences for and cost-effectiveness of different service models for delivering outpatient parenteral antimicrobial therapy.

Risk factors for emergency presentation with lung and colorectal cancers: A systematic review (2015)
Journal Article
Mitchell, E. D., Pickwell-Smith, B., & Macleod, U. (2015). Risk factors for emergency presentation with lung and colorectal cancers: A systematic review. BMJ open, 5(4), Article e006965. https://doi.org/10.1136/bmjopen-2014-006965

© 2015, BMJ. All rights reserved. Objective: To identify patient and practitioner factors that influence cancer diagnosis via emergency presentation (EP). Design: Systematic review. Data sources: MEDLINE, EMBASE, CINAHL, EBM Reviews, Science and Soci... Read More about Risk factors for emergency presentation with lung and colorectal cancers: A systematic review.

The role of primary care in cancer diagnosis via emergency presentation: qualitative synthesis of significant event reports (2015)
Journal Article
Mitchell, E. D., Rubin, G., Merriman, L., & Macleod, U. (2015). The role of primary care in cancer diagnosis via emergency presentation: qualitative synthesis of significant event reports. The British Journal of Cancer, 112(S1), S50-S56. https://doi.org/10.1038/bjc.2015.42

Background:
Patients diagnosed with cancer in the context of an emergency presentation (EP) have poorer outcomes. It is often assumed that such patients present to the emergency department without consulting their general practitioner (GP). Little w... Read More about The role of primary care in cancer diagnosis via emergency presentation: qualitative synthesis of significant event reports.

Is increased time to diagnosis and treatment in symptomatic cancer associated with poorer outcomes? Systematic review (2015)
Journal Article
Neal, R. D., Tharmanathan, P., France, B., Din, N. U., Cotton, S., Fallon-Ferguson, J., Hamilton, W., Hendry, A., Hendry, M., Lewis, R., Macleod, U., Mitchell, E. D., Pickett, M., Rai, T., Shaw, K., Stuart, N., Tørring, M. L., Wilkinson, C., Williams, B., Williams, N., & Emery, J. (2015). Is increased time to diagnosis and treatment in symptomatic cancer associated with poorer outcomes? Systematic review. The British Journal of Cancer, 112, S92-S107. https://doi.org/10.1038/bjc.2015.48

© 2015 Cancer Research UK. Background: It is unclear whether more timely cancer diagnosis brings favourable outcomes, with much of the previous evidence, in some cancers, being equivocal. We set out to determine whether there is an association betwee... Read More about Is increased time to diagnosis and treatment in symptomatic cancer associated with poorer outcomes? Systematic review.

Predictors of anxiety and depression in people with colorectal cancer (2013)
Journal Article
Gray, N. M., Hall, S. J., Browne, S., Johnston, M., Lee, A. J., Macleod, U., Mitchell, E. D., Samuel, L., & Campbell, N. C. (2014). Predictors of anxiety and depression in people with colorectal cancer. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 22(2), 307-314. https://doi.org/10.1007/s00520-013-1963-8

Background: People living with colorectal cancer are at risk of anxiety and depression. We investigated what factors were most highly associated with these. Methods: Four hundred and ninety-six people with colorectal cancer completed the Hospital Anx... Read More about Predictors of anxiety and depression in people with colorectal cancer.

Modifiable and fixed factors predicting quality of life in people with colorectal cancer (2011)
Journal Article
Gray, N. M., Hall, S. J., Browne, S., Macleod, U., Mitchell, E., Lee, A. J., Johnston, M., Wyke, S., Samuel, L., Weller, D., & Campbell, N. C. (2011). Modifiable and fixed factors predicting quality of life in people with colorectal cancer. The British Journal of Cancer, 104(11), 1697-1703. https://doi.org/10.1038/bjc.2011.155

BACKGROUND: People with colorectal cancer have impaired quality of life (QoL). We investigated what factors were most highly associated with it. METHODS: Four hundred and ninety-six people with colorectal cancer completed questionnaires about QoL, fu... Read More about Modifiable and fixed factors predicting quality of life in people with colorectal cancer.