Outputs (404)

Supervised Exercise Therapy for Intermittent Claudication: A Propensity Score Matched Analysis of Retrospective Data on Long Term Cardiovascular Outcomes (2023)
Journal Article
Ravindhran, B., Lim, A. J., Kurian, T., Walshaw, J., Hitchman, L. H., Lathan, R., Smith, G. E., Carradice, D., Chetter, I. C., & Pymer, S. (in press). Supervised Exercise Therapy for Intermittent Claudication: A Propensity Score Matched Analysis of Retrospective Data on Long Term Cardiovascular Outcomes. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, https://doi.org/10.1016/j.ejvs.2023.11.040

Objective: This study aimed to explore the long term outcomes of patients with intermittent claudication (IC) who completed supervised exercise therapy (SET) vs. those who declined or prematurely discontinued SET, focusing on the incidence of chronic... Read More about Supervised Exercise Therapy for Intermittent Claudication: A Propensity Score Matched Analysis of Retrospective Data on Long Term Cardiovascular Outcomes.

Pathways to care for Long COVID and for long-term conditions from patients' and clinicians' perspective (2023)
Journal Article
Turk, F., Sweetman, J., Allsopp, G., Crooks, M., Cuthbertson, D. J., Gabbay, M., Hishmeh, L., Lip, G. Y., Strain, W. D., Williams, N., Wootton, D., Banerjee, A., & van der Feltz-Cornelis, C. (2023). Pathways to care for Long COVID and for long-term conditions from patients' and clinicians' perspective. Journal of Evidence-Based Medicine, 16(4), 435-437. https://doi.org/10.1111/jebm.12563

Molecular mechanisms of action of negative pressure wound therapy: A systematic review (2023)
Journal Article
Ravindhran, B., Schafer, N., Howitt, A., Carradice, D., Smith, G., & Chetter, I. (2023). Molecular mechanisms of action of negative pressure wound therapy: A systematic review. Expert Reviews in Molecular Medicine, 25, Article e29. https://doi.org/10.1017/erm.2023.24

Negative pressure wound therapy (NPWT) has significantly advanced wound care and continues to find new applications. Its effects at a molecular level however, remain a subject of debate. The aim of this systematic review is to summarize the current e... Read More about Molecular mechanisms of action of negative pressure wound therapy: A systematic review.

Associations between physical activity, sedentary behaviour, and alcohol consumption among UK adults: Findings from the Health Behaviours during the COVID-19 pandemic (HEBECO) study (2023)
Journal Article
Akwa, L. G., Smith, L., Twiddy, M., Abt, G., Garnett, C., Oldham, M., Shahab, L., & Herbec, A. (2023). Associations between physical activity, sedentary behaviour, and alcohol consumption among UK adults: Findings from the Health Behaviours during the COVID-19 pandemic (HEBECO) study. PLoS ONE, 18(10 October), Article e0287199. https://doi.org/10.1371/journal.pone.0287199

Introduction The COVID-19 pandemic and attendant lockdowns have had a substantial negative effect on alcohol consumption and physical activity globally. Pre-pandemic evidence in the adult population suggests that higher levels of physical activity we... Read More about Associations between physical activity, sedentary behaviour, and alcohol consumption among UK adults: Findings from the Health Behaviours during the COVID-19 pandemic (HEBECO) study.

High-intensity interval training in patients with intermittent claudication (2023)
Presentation / Conference Contribution
Pymer, S., Harwood, A. E., Prosser, J., Waddell, A., Rhavindhran, B., McGregor, G., Ibeggazene, S., Huang, C., Twiddy, M., Nicholls, A. R., Ingle, L., Carroll, S., He, H., Long, J., Rooms, M., & Chetter, I. C. High-intensity interval training in patients with intermittent claudication. Presented at 2022 Vascular Society of Great Britain and Ireland Annual Scientific Meeting, Brighton, UK

Objective: Provision, uptake, adherence, and completion rates for supervised exercise programs (SEP) for intermittent claudication (IC) are low. A shorter, more time-efficient, 6-week, high-intensity interval training (HIIT) program may be an effecti... Read More about High-intensity interval training in patients with intermittent claudication.

A preoperative supervised exercise program potentially improves long-term survival after elective abdominal aortic aneurysm repair (2023)
Presentation / Conference Contribution
Sethi, S., Ravindhran, B., Long, J., Gurung, R., Huang, C., Smith, G. E., Carradice, D., Wallace, T., Ibeggazene, S., Chetter, I. C., & Pymer, S. A preoperative supervised exercise program potentially improves long-term survival after elective abdominal aortic aneurysm repair. Presented at 2023 Vascular Annual Meeting of the Society for Vascular Surgery, National Harbor, Maryland

Objective: A preoperative supervised exercise program (SEP) improves cardiorespiratory fitness and perioperative outcomes for patients undergoing elective abdominal aortic aneurysm (AAA) repair. The aim of this study was to assess the effect of a pre... Read More about A preoperative supervised exercise program potentially improves long-term survival after elective abdominal aortic aneurysm repair.

Breathlessness limiting exertion in very old adults: findings from the Newcastle 85+ study (2023)
Journal Article
Johnson, M. J., Pitel, L., Currow, D. C., Forbes, C., Soyiri, I., & Robinson, L. (2023). Breathlessness limiting exertion in very old adults: findings from the Newcastle 85+ study. Age and ageing, 52(9), Article afad155. https://doi.org/10.1093/ageing/afad155

INTRODUCTION: Long-term breathlessness is more common with age. However, in the oldest old (>85years), little is known about the prevalence, or impact of breathlessness. We estimated breathlessness limiting exertion prevalence and explored (i) associ... Read More about Breathlessness limiting exertion in very old adults: findings from the Newcastle 85+ study.

A randomised phase 2a study to investigate the effects of blocking interleukin-33 with tozorakimab in patients hospitalised with COVID-19: ACCORD-2 (2023)
Journal Article
Wilkinson, T., De Soyza, A., Carroll, M., Chalmers, J. D., Crooks, M. G., Griffiths, G., Shankar-Hari, M., Ho, L. P., Horsley, A., Kell, C., Lara, B., Mishra, B., Moate, R., Page, C., Pandya, H., Raw, J., Reid, F., Saralaya, D., Scott, I. C., Siddiqui, S., …on behalf of The ACCORD Collaborative Group. (2023). A randomised phase 2a study to investigate the effects of blocking interleukin-33 with tozorakimab in patients hospitalised with COVID-19: ACCORD-2. ERJ Open Research, 9(5), Article 00249-2023. https://doi.org/10.1183/23120541.00249-2023

Background Increased serum interleukin (IL)-33 predicts poor outcomes in patients hospitalised with coronavirus disease 2019 (COVID-19). We examined the efficacy and safety of tozorakimab, a monoclonal antibody that neutralises IL-33, in improving ou... Read More about A randomised phase 2a study to investigate the effects of blocking interleukin-33 with tozorakimab in patients hospitalised with COVID-19: ACCORD-2.

Surgical and rehabilitation outcomes of patients undergoing through knee amputation compared with above knee amputation (2023)
Journal Article
Gordon, H., Hebenton, J., Davie-Smith, F., Twiddy, M., Smith, G., & Carradice, D. (2023). Surgical and rehabilitation outcomes of patients undergoing through knee amputation compared with above knee amputation. Journal of Vascular Societies Great Britain and Ireland, 2(4), 208-214. https://doi.org/10.54522/jvsgbi.2023.081

Background: Through knee amputation (TKA) may offer benefits over above knee amputation (AKA) in patients unsuitable for below knee amputation. This retrospective analysis compared surgical and rehabilitation outcomes post TKA and AKA.

Methods: Al... Read More about Surgical and rehabilitation outcomes of patients undergoing through knee amputation compared with above knee amputation.

Long Covid active case finding study protocol: A co-produced community-based pilot within the STIMULATE-ICP study (Symptoms, Trajectory, Inequalities and Management: Understanding Long-COVID to Address and Transform Existing Integrated Care Pathways) (2023)
Journal Article
Alwan, N. A., Clutterbuck, D., Pantelic, M., Hayer, J., Fisher, L., Hishmeh, L., Heightman, M., Allsopp, G., Wootton, D., Khan, A., Hastie, C., Jackson, M., Rayner, C., Brown, D., Parrett, E., Jones, G., Smith, K., Clarke, R., McFarland, S., Gabbay, M., …Cleary, N. (2023). Long Covid active case finding study protocol: A co-produced community-based pilot within the STIMULATE-ICP study (Symptoms, Trajectory, Inequalities and Management: Understanding Long-COVID to Address and Transform Existing Integrated Care Pathways). PLoS ONE, 18(7 July), Article e0284297. https://doi.org/10.1371/journal.pone.0284297

Background and aim Long Covid is a significant public health concern with potentially negative implications for health inequalities. We know that those who are already socially disadvantaged in society are more exposed to COVID-19, experience the wor... Read More about Long Covid active case finding study protocol: A co-produced community-based pilot within the STIMULATE-ICP study (Symptoms, Trajectory, Inequalities and Management: Understanding Long-COVID to Address and Transform Existing Integrated Care Pathways).