Aoife C. Lowney
Understanding What Influences the Health-Related Quality of Life of Hemodialysis Patients: A Collaborative Study in England and Ireland
Lowney, Aoife C.; Myles, Helena T.; Bristowe, Katherine; Lowney, Eanna L.; Shepherd, Katie; Murphy, Marie; O'Brien, Tony; Casserly, Liam; McQuillan, Regina; Plant, William D.; Conlon, Peter J.; Vinen, Catherine; Eustace, Joseph A.; Murtagh, Fliss E.M.
Authors
Helena T. Myles
Katherine Bristowe
Eanna L. Lowney
Katie Shepherd
Marie Murphy
Tony O'Brien
Liam Casserly
Regina McQuillan
William D. Plant
Peter J. Conlon
Catherine Vinen
Joseph A. Eustace
Professor Fliss Murtagh F.Murtagh@hull.ac.uk
Professor of Palliative Care
Abstract
Context: The international cohort of hemodialysis patients is aging and increasing in number. Nephrologists have a therapeutic relationship with their patients that may span decades. Often overlooked components of chronic disease management include symptom control and assessment of health-related quality of life (HRQoL).
Objectives: This study describes the symptom profile of a large cohort of patients with end-stage renal disease on hemodialysis in England and Ireland and evaluates how symptom burden and other factors influence quality-of-life scores.
Methods: A prospective cross-sectional observational study of hemodialysis patients was conducted in Ireland and England during 2011 and 2012. Two validated clinical tools were used to determine HRQoL and symptom burden. Demographic and clinical data were examined, and regression analysis was used to determine associations with HRQoL scores.
Results: A total of 893 patients on hemodialysis (mean [SD] age 64 [16] years) had a high symptom burden and poor HRQoL compared with population norms. Specifically, 64% of patients reported pain (95% confidence interval 61%-67%) and 79% reported weakness (95% confidence interval 75%-81%). A total of 43 percent of patients reported between six and 10 symptoms in the week preceding the survey. HRQoL was significantly and independently associated with poor mobility and pain and remained significant after adjusting for variations in clinical characteristics. Being listed on a transplant wait-list register was positively associated with HRQoL.
Conclusion: These findings illustrate the high symptom burden and poor HRQoL of the hemodialysis population. Emphasis during clinical reviews on pain assessment and on assessing mobility plus interventions, such as pain management and physiotherapy/occupational therapy, are practical ways for renal teams to help improve patients' quality of life.
Citation
Lowney, A. C., Myles, H. T., Bristowe, K., Lowney, E. L., Shepherd, K., Murphy, M., …Murtagh, F. E. (2015). Understanding What Influences the Health-Related Quality of Life of Hemodialysis Patients: A Collaborative Study in England and Ireland. Journal of pain and symptom management, 50(6), 778-785. https://doi.org/10.1016/j.jpainsymman.2015.07.010
Journal Article Type | Article |
---|---|
Acceptance Date | Jul 15, 2015 |
Online Publication Date | Nov 27, 2015 |
Publication Date | 2015-12 |
Deposit Date | Jun 8, 2022 |
Journal | Journal of Pain and Symptom Management |
Print ISSN | 0885-3924 |
Electronic ISSN | 1873-6513 |
Publisher | Elsevier |
Volume | 50 |
Issue | 6 |
Pages | 778-785 |
DOI | https://doi.org/10.1016/j.jpainsymman.2015.07.010 |
Public URL | https://hull-repository.worktribe.com/output/1350514 |
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