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Minimum Sample Size Requirements for a Validation Study of The Schizophrenia Quality of Life Scale-Revision 4 (SQLS-R4)

Martin, Colin R.; Larkin, Derek

Authors

Colin R. Martin

Derek Larkin



Abstract

Purpose: The Schizophrenia Quality of Life Scale-Revision 4 (SQLS-R4) is a widely used self-report quality of life measure used in a broad range of clinical contexts, from primary research to clinical trials. International use of the measure has led to translated versions validated for local context. Most translation and validation studies of the SQLS-R4 have been conducted with modest N, at the threshold of acceptability of even the most liberal recommendations for validation studies. Given the comparatively large number of items in the SQLS-R4 (N=33), low N studies could potentially be underpowered limiting validity and reliability. Using sample sizes from published studies as a baseline, the current investigation sought to determine a minimum sample size for an SQLS-R4 translation/validation study.
Methods: A model specification based on the two-factor structure of the SQLS-R4 was constructed to calculate an acceptable model fit based on the sample size used in most SQLS-R4 translation/validation studies (N=100). A series of Monte Carlo simulations was then conducted to determine the sample size required to offer a good fit to data for an adequately powered study.

Results: The series of simulations conducted suggests that a minimum sample size for an adequately powered validation/translation study of the SQLS-R4 to provide a good fit to data is N=160.

Conclusion: Sample size determination of SQLS-R4 validation/translation studies should be informed by the intrinsic measurement characteristics of the measure to ensure an adequately powered study.
Keywords : Schizophrenia Quality of Life-Revision 4 (SQLS-R4), simulation, sample size, questionnaire

Citation

Martin, C. R., & Larkin, D. (2018). Minimum Sample Size Requirements for a Validation Study of The Schizophrenia Quality of Life Scale-Revision 4 (SQLS-R4). Journal of basic and clinical health sciences, 2(3), 076-081. https://doi.org/10.30621/jbachs.2018.411

Journal Article Type Article
Acceptance Date Jun 22, 2018
Online Publication Date Oct 9, 2018
Publication Date Oct 9, 2018
Deposit Date Aug 5, 2019
Publicly Available Date Mar 30, 2024
Journal Journal of Basic and Clinical Health Sciences
Print ISSN 2458-8938
Peer Reviewed Peer Reviewed
Volume 2
Issue 3
Pages 076-081
DOI https://doi.org/10.30621/jbachs.2018.411
Keywords Schizophrenia Quality of Life-Revision 4 (SQLS-R4), simulation, sample size, questionnaire
Public URL https://hull-repository.worktribe.com/output/2308550
Publisher URL http://jbachs.org/abstract.php?id=37
Related Public URLs https://research.edgehill.ac.uk/en/publications/minimum-sample-size-requirements-for-a-validation-study-of-the-sc-2