Recent progress in the development of organometallics for the treatment of cancer

Murray, Benjamin S.; Dyson, Paul J.

Abstract

From their early successes in medicine, organometallic compounds continue to attract interest as potential chemotherapeutics to treat a range of diseases. Here, we show from recent literature selected largely from the last two years that organometallics offer unique opportunities in medicine and, increasingly, a mechanistic-based approach is applied to their development, which has not always been the case.

Citation

Murray, B. S., & Dyson, P. J. (2020). Recent progress in the development of organometallics for the treatment of cancer. Current opinion in chemical biology, 56, 28-34. https://doi.org/10.1016/j.cbpa.2019.11.001

• Journal Article Type: Review
• Acceptance Date: Nov 1, 2019
• Online Publication Date: Dec 5, 2019
• Publication Date: 2020-06
• Deposit Date: Jan 7, 2020
• Publicly Available Date: Dec 6, 2020
• Journal: Current Opinion in Chemical Biology
• Print ISSN: 1367-5931
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 56
• Pages: 28-34
• DOI: https://doi.org/10.1016/j.cbpa.2019.11.001
• Keywords: Analytical Chemistry; Biochemistry; Bioorganometallic chemistry; Bioinorganic chemistry; Metallodrugs; Chemotherapy
• Public URL: https://hull-repository.worktribe.com/output/3294967
• Additional Information: This article is maintained by: Elsevier; Article Title: Recent progress in the development of organometallics for the treatment of cancer; Journal Title: Current Opinion in Chemical Biology; CrossRef DOI link to publisher maintained version: https://doi.org/10.1016/j.cbpa.2019.11.001; Content Type: article; Copyright: © 2019 Elsevier Ltd. All rights reserved.
• Contract Date: Jan 7, 2020