Hirotsugu Tomiyasu
A study of allosteric binding behaviour of a 1,3-alternate thiacalix[4]arene-based receptor using fluorescence signal
Tomiyasu, Hirotsugu; Jin, Cheng-Cheng; Ni, Xin-Long; Zeng, Xi; Redshaw, Carl; Yamato, Takehiko
Authors
Cheng-Cheng Jin
Xin-Long Ni
Xi Zeng
Professor Carl Redshaw C.Redshaw@hull.ac.uk
Professor of Inorganic Materials Chemistry and REF Lead for Chemistry
Takehiko Yamato
Abstract
A novel heteroditopic thiacalix[4]arene receptor L possessing 1,3-alternate conformation, which contains two pyrene moieties attached to the lower rim via urea linkages together with a crown ether moiety appended at the opposite side of the thiacalix[4]arene cavity, has been synthesized. The complexation behaviour of receptor L was studied by means of fluorescence spectra and ¹H NMR titration experiments in the presence of K⁺ ions and a variety of other anions. The results suggested that receptor L can complex efficiently via the urea cavity or the crown ether moiety, and a positive/negative allosteric effect operating in receptor L was observed.
Citation
Tomiyasu, H., Jin, C., Ni, X., Zeng, X., Redshaw, C., & Yamato, T. (2014). A study of allosteric binding behaviour of a 1,3-alternate thiacalix[4]arene-based receptor using fluorescence signal. Organic & biomolecular chemistry, 12(27), 4917-4923. https://doi.org/10.1039/c4ob00551a
Journal Article Type | Article |
---|---|
Acceptance Date | May 9, 2014 |
Online Publication Date | May 12, 2014 |
Publication Date | Jul 21, 2014 |
Deposit Date | Jul 8, 2015 |
Publicly Available Date | Jul 8, 2015 |
Journal | Organic & biomolecular chemistry |
Print ISSN | 1477-0520 |
Electronic ISSN | 1477-0539 |
Publisher | Royal Society of Chemistry |
Peer Reviewed | Peer Reviewed |
Volume | 12 |
Issue | 27 |
Pages | 4917-4923 |
DOI | https://doi.org/10.1039/c4ob00551a |
Keywords | Fluorescence signal, Allosteric binding behaviour |
Public URL | https://hull-repository.worktribe.com/output/376133 |
Publisher URL | http://pubs.rsc.org/en/Content/ArticleLanding/2014/OB/c4ob00551a#!divAbstract |
Additional Information | Author's accepted manuscript of article published in: Organic & biomolecular chemistry, 2014, v.12, issue 27. |
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©2015 University of Hull
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