Professor Lee Ingle L.Ingle@hull.ac.uk
Professor
Objective: To assess the prognostic implications of the 6-minute walk test (6-MWT) distance measured twice, one year apart, in a large sample of patients with chronic heart failure (CHF) followed for an extended period ( > . 8. years from baseline). Material and methods: Patients undertook a 6-MWT at baseline and at one year, and were followed up for 8. years from baseline. Results: Six hundred patients (median [inter-quartile range, IQR]) (age 78 [72-84] years; 75% males; body mass index 27 [25-31] kg·m -2 ; left ventricular ejection fraction 34 [26-38] %) were included. At baseline, median 6-MWT distance was 232 (60-386) m. There was no significant change in 6-MWT distance at one year (change -12m; P=0.533). During a median follow-up of 8.0years in survivors, 396patients had died (66%). Four variables were independent predictors of all-cause mortality in a multivariable Cox model (adjusted for body mass index, age, QRS duration, left ventricular ejection fraction); increasing NT pro-BNP, decreasing 6-MWT distance at 1year, decreasing haemoglobin, and increasing urea. Conclusions: Distance walked during the 6-MWT is an independent predictor of all-cause mortality in patients with CHF. In survivors, the 6-MWT distance is stable at 1 year. The 6-MWT distance at 1 year carries similar prognostic information. © 2014 Elsevier Masson SAS.
Ingle, L., Cleland, J. G., & Clark, A. L. (2014). The relation between repeated 6-minute walk test performance and outcome in patients with chronic heart failure. Annals of physical and rehabilitation medicine, 57(4), 244-253. https://doi.org/10.1016/j.rehab.2014.03.004
Journal Article Type | Article |
---|---|
Acceptance Date | Mar 3, 2014 |
Online Publication Date | May 2, 2014 |
Publication Date | 2014-06 |
Deposit Date | Dec 16, 2015 |
Publicly Available Date | Nov 23, 2017 |
Journal | Annals of physical and rehabilitation medicine |
Print ISSN | 1877-0657 |
Electronic ISSN | 1877-0665 |
Publisher | Elsevier |
Peer Reviewed | Peer Reviewed |
Volume | 57 |
Issue | 4 |
Pages | 244-253 |
DOI | https://doi.org/10.1016/j.rehab.2014.03.004 |
Keywords | Repeat testing, 6-minute walk test, Risk, Chronic heart failure |
Public URL | https://hull-repository.worktribe.com/output/382920 |
Publisher URL | http://www.sciencedirect.com/science/article/pii/S1877065714000475 |
Copyright Statement | © 2014. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ |
Additional Information | This article is maintained by: Elsevier; Article Title: The relation between repeated 6-minute walk test performance and outcome in patients with chronic heart failure; Journal Title: Annals of Physical and Rehabilitation Medicine; CrossRef DOI link to publisher maintained version: http://dx.doi.org/10.1016/j.rehab.2014.03.004; Content Type: article; Copyright: Copyright © 2014 Elsevier Masson SAS. All rights reserved. |
Article.pdf
(392 Kb)
PDF
Publisher Licence URL
http://creativecommons.org/licenses/by-nc-nd/4.0/
Copyright Statement
© 2014. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
Relation Between Thyroid Function and Mortality in Patients With Chronic Heart Failure
(2020)
Journal Article
Prevalence and incidence of atrial fibrillation in ambulatory patients with heart failure
(2019)
Journal Article
About Repository@Hull
Administrator e-mail: repository@hull.ac.uk
This application uses the following open-source libraries:
Apache License Version 2.0 (http://www.apache.org/licenses/)
Apache License Version 2.0 (http://www.apache.org/licenses/)
SIL OFL 1.1 (http://scripts.sil.org/OFL)
MIT License (http://opensource.org/licenses/mit-license.html)
CC BY 3.0 ( http://creativecommons.org/licenses/by/3.0/)
Advanced Search