Reply to “Analysis of NO and its metabolites by mass spectrometry. Comment on ‘Detection of nitric oxide in tissue samples by ESI-MS’”

Zheng, Shen; Zheng, Shen; Webster, Abigail; Welham, Kevin J.; Dyer, Charlotte E.; Greenman, John; Haswell, Stephen J.; Zheng, Shen; Webster, Abigail; Welham, Kevin J.; Dyer, Charlotte E.; Greenman, John; Haswell, Stephen J.; Zheng, Shen; Webster, Abigail; Welham, Kevin J.; Dyer, Charlotte E.; Greenman, John; Haswell, Stephen J.; Zheng, Shen; Webster, Abigail; Webster, Abigail; Welham, Kevin; Welham, Kevin J.; Dyer, Charlotte E.; Dyer, Charlotte E.; Greenman, John; Greenman, John; Haswell, Stephen J.; Haswell, Stephen J.

Abstract

Comment by Tsikas et al. (Analyst, 2011, DOI: 10.1039/c0an00411a) on the preliminary work by Shen and colleagues (Analyst, 2010, 135, 302) describing the use of ESI-MS/MS for the detection of methylpiperazinobenzenediamine, as a probe for NO in tissue samples, have been addressed in this communication. The article concludes that the points raised by Tsikas represent a logical progression to the research reported and indicate the way forward in realising appropriate analytical methodology.

Citation

Zheng, S., Webster, A., Zheng, S., Welham, K. J., Dyer, C. E., Greenman, J., …Haswell, S. J. (2011). Reply to “Analysis of NO and its metabolites by mass spectrometry. Comment on ‘Detection of nitric oxide in tissue samples by ESI-MS’”. Analyst, 136(2), 411-411. https://doi.org/10.1039/c0an00729c

• Journal Article Type: Article
• Acceptance Date: Dec 31, 2011
• Publication Date: Dec 31, 2011
• Journal: ANALYST
• Print ISSN: 0003-2654
• Electronic ISSN: 1364-5528
• Publisher: Royal Society of Chemistry
• Volume: 136
• Issue: 2
• Pages: 411-411
• DOI: https://doi.org/10.1039/c0an00729c
• Keywords: Analytical Chemistry; Spectroscopy; Electrochemistry; Biochemistry; Environmental Chemistry
• Public URL: https://hull-repository.worktribe.com/output/396322