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The effect of glucose administration on the recollection and familiarity components of recognition memory

Sünram-Lea, Sandra I.; Dewhurst, Stephen A.; Foster, Jonathan K.


Sandra I. Sünram-Lea

Jonathan K. Foster


Previous research has demonstrated that glucose administration facilitates long-term memory performance. The aim of the present research was to evaluate the effect of glucose administration on different components of long-term recognition memory. Fifty-six healthy young individuals received (a) a drink containing 25 g of glucose or (b) an inert placebo drink. Recollection and familiarity components of recognition memory were measured using the 'remember-know' paradigm. The results revealed that glucose administration led to significantly increased proportion of recognition responses based on recollection, but had no effect on the proportion of recognition responses made through participants' detection of stimulus familiarity. Consequently, the data suggest that glucose administration appears to facilitate recognition memory that is accompanied by recollection of contextual details and episodic richness. The findings also suggest that memory tasks that result in high levels of hippocampal activity may be more likely to be enhanced by glucose administration than tasks that are less reliant on medial temporal lobe structures. © 2007 Elsevier B.V. All rights reserved.


Sünram-Lea, S. I., Dewhurst, S. A., & Foster, J. K. (2008). The effect of glucose administration on the recollection and familiarity components of recognition memory. Biological Psychology, 77(1), 69-75.

Journal Article Type Article
Acceptance Date Sep 12, 2007
Online Publication Date Sep 15, 2007
Publication Date 2008-01
Print ISSN 0301-0511
Publisher Elsevier
Peer Reviewed Peer Reviewed
Volume 77
Issue 1
Pages 69-75
Keywords glucose aspartame recognition memory recollection familiarity healthy young adults hippocampal acetylcholine-release insulin improves memory healthy-young adults cognitive performance alzheimers-disease task-difficulty brain activity mental effort spatial
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