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Microfluidic platforms for performing surface-based clinical assays

Tarn, Mark D.; Pamme, Nicole

Authors

Mark D. Tarn



Abstract

The need for fast, specific and portable diagnostic systems for clinical assays has, in recent years, led to an explosion of research into microfluidic chip-based immunoassays towards rapid point-of-care analysis. Such devices exploit small dimensions, superior fluidic control and low reagent volumes to allow a number of clinically important procedures to be achieved with improvements on conventional methods, many of which rely on the surface-based binding of antigens to antibodies. Here, we discuss recent developments and innovations in the area of on-chip surface-based immunoassays and provide an outlook on the potential of such platforms for future diagnostics.

Journal Article Type Article
Publication Date 2011-09
Journal EXPERT REVIEW OF MOLECULAR DIAGNOSTICS
Print ISSN 1473-7159
Electronic ISSN 1744-8352
Publisher Taylor & Francis
Peer Reviewed Peer Reviewed
Volume 11
Issue 7
Pages 711-720
APA6 Citation Tarn, M. D., & Pamme, N. (2011). Microfluidic platforms for performing surface-based clinical assays. Expert review of molecular diagnostics, 11(7), 711-720. https://doi.org/10.1586/ERM.11.59
DOI https://doi.org/10.1586/ERM.11.59
Keywords Clinical assays; Diagnostics; Heterogeneous immunoassays; Magnetic particles; Microfluidics; Particles; Surface-based
Publisher URL https://www.tandfonline.com/doi/full/10.1586/erm.11.59
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