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Microfluidic platforms for performing surface-based clinical assays

Tarn, Mark D.; Pamme, Nicole


Mark D. Tarn


The need for fast, specific and portable diagnostic systems for clinical assays has, in recent years, led to an explosion of research into microfluidic chip-based immunoassays towards rapid point-of-care analysis. Such devices exploit small dimensions, superior fluidic control and low reagent volumes to allow a number of clinically important procedures to be achieved with improvements on conventional methods, many of which rely on the surface-based binding of antigens to antibodies. Here, we discuss recent developments and innovations in the area of on-chip surface-based immunoassays and provide an outlook on the potential of such platforms for future diagnostics.

Journal Article Type Article
Publication Date 2011-09
Print ISSN 1473-7159
Electronic ISSN 1744-8352
Publisher Taylor & Francis
Peer Reviewed Peer Reviewed
Volume 11
Issue 7
Pages 711-720
APA6 Citation Tarn, M. D., & Pamme, N. (2011). Microfluidic platforms for performing surface-based clinical assays. Expert review of molecular diagnostics, 11(7), 711-720.
Keywords Clinical assays; Diagnostics; Heterogeneous immunoassays; Magnetic particles; Microfluidics; Particles; Surface-based
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