Mark D. Tarn
Microfluidic platforms for performing surface-based clinical assays
Tarn, Mark D.; Pamme, Nicole
Authors
Nicole Pamme
Abstract
The need for fast, specific and portable diagnostic systems for clinical assays has, in recent years, led to an explosion of research into microfluidic chip-based immunoassays towards rapid point-of-care analysis. Such devices exploit small dimensions, superior fluidic control and low reagent volumes to allow a number of clinically important procedures to be achieved with improvements on conventional methods, many of which rely on the surface-based binding of antigens to antibodies. Here, we discuss recent developments and innovations in the area of on-chip surface-based immunoassays and provide an outlook on the potential of such platforms for future diagnostics.
Citation
Tarn, M. D., & Pamme, N. (2011). Microfluidic platforms for performing surface-based clinical assays. Expert review of molecular diagnostics, 11(7), 711-720. https://doi.org/10.1586/ERM.11.59
Journal Article Type | Article |
---|---|
Online Publication Date | Jan 9, 2014 |
Publication Date | 2011-09 |
Journal | EXPERT REVIEW OF MOLECULAR DIAGNOSTICS |
Print ISSN | 1473-7159 |
Electronic ISSN | 1744-8352 |
Publisher | Taylor and Francis |
Peer Reviewed | Peer Reviewed |
Volume | 11 |
Issue | 7 |
Pages | 711-720 |
DOI | https://doi.org/10.1586/ERM.11.59 |
Keywords | Clinical assays; Diagnostics; Heterogeneous immunoassays; Magnetic particles; Microfluidics; Particles; Surface-based |
Public URL | https://hull-repository.worktribe.com/output/424115 |
Publisher URL | https://www.tandfonline.com/doi/full/10.1586/erm.11.59 |
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