Mark D. Tarn
Microfluidic platforms for performing surface-based clinical assays
Tarn, Mark D.; Pamme, Nicole
The need for fast, specific and portable diagnostic systems for clinical assays has, in recent years, led to an explosion of research into microfluidic chip-based immunoassays towards rapid point-of-care analysis. Such devices exploit small dimensions, superior fluidic control and low reagent volumes to allow a number of clinically important procedures to be achieved with improvements on conventional methods, many of which rely on the surface-based binding of antigens to antibodies. Here, we discuss recent developments and innovations in the area of on-chip surface-based immunoassays and provide an outlook on the potential of such platforms for future diagnostics.
Tarn, M. D., & Pamme, N. (2011). Microfluidic platforms for performing surface-based clinical assays. Expert review of molecular diagnostics, 11(7), 711-720. https://doi.org/10.1586/ERM.11.59
|Journal Article Type||Article|
|Online Publication Date||Jan 9, 2014|
|Journal||EXPERT REVIEW OF MOLECULAR DIAGNOSTICS|
|Publisher||Taylor and Francis|
|Peer Reviewed||Peer Reviewed|
|Keywords||Clinical assays; Diagnostics; Heterogeneous immunoassays; Magnetic particles; Microfluidics; Particles; Surface-based|
This file is under embargo due to copyright reasons.
You might also like
Diamagnetic repulsion of particles for multilaminar flow assays
On-chip diamagnetic repulsion in continuous flow
Tailoring pH-responsive acrylic acid microgels with hydrophobic crosslinks for drug release