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Non-invasive estimation of left atrial dominant frequency in atrial fibrillation from different electrode sites : insight from body surface potential mapping

Bojarnejad, Marjan; Blake, James R; Bourke, John; Shepherd, Ewan; Murray, Alan; Langley, Philip

Authors

Marjan Bojarnejad

James R Blake

John Bourke

Ewan Shepherd

Alan Murray



Abstract

The dominant driving sources of atrial fibrillation are often found in the left atrium, but the expression of left atrial activation on the body surface is poorly understood. Using body surface potential mapping and simultaneous invasive measurements of left atrial activation our aim was to describe the expression of the left atrial dominant fibrillation frequency across the body surface. 20 patients in atrial fibrillation were studied. The spatial distributions of the dominant atrial fibrillation frequency across anterior and posterior sites on the body surface were quantified. Their relationship with invasive left atrial dominant fibrillation frequency was assessed by linear regression analysis, and the coefficient of determination was calculated for each body surface site. The correlation between intracardiac and body surface dominant frequency was significantly higher with posterior compared with anterior sites (coefficient of determination 67±8% vs 48±2%, p<0.001). The site with largest coefficient of determination was 79.6% (p<0.001) and was a posterior site. In comparison with the site closest to lead V1 it had a coefficient of determination of 23.0% (p=0.033), and with the posterior body surface site closest to lead V9 had a coefficient of determination of 70.3% (p<0.001). Left atrial dominant fibrillation frequency was more closely represented at posterior body surface sites.

Journal Article Type Article
Publication Date 2014-10
Journal Journal of atrial fibrillation
Print ISSN 1941-6911
Electronic ISSN 1941-6911
Peer Reviewed Peer Reviewed
Volume 7
Issue 3
Pages 6-10
APA6 Citation Bojarnejad, M., Blake, J. R., Bourke, J., Shepherd, E., Murray, A., & Langley, P. (2014). Non-invasive estimation of left atrial dominant frequency in atrial fibrillation from different electrode sites : insight from body surface potential mapping. Journal of atrial fibrillation, 7(3), 6-10
Keywords Atrial arrhythmia, Atrial fibrillation, Intra-atrial electrograms, Body surface potential mapping, Signal processing
Publisher URL http://www.jafib.com/published.php?type=full&id=1131&is=previous_issue&f=full
Additional Information This is a copy of an open access article published in Journal of atrial fibrillation, v.7 issue 3.

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Copyright Statement
This work is licensed under a Creative Commons Attribution 3.0 Unported License





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