Skip to main content

Research Repository

Advanced Search

Accuracy of pulse interval timing in ambulatory blood pressure measurement

Kane, Sarah A.; Blake, James R.; McArdle, Frank J.; Langley, Philip; Sims, Andrew J.


Sarah A. Kane

James R. Blake

Frank J. McArdle

Philip Langley

Andrew J. Sims


Blood pressure (BP) monitors rely on pulse detection. Some blood pressure monitors use pulse timings to analyse pulse interval variability for arrhythmia screening, but this assumes that the pulse interval timings detected from BP cuffs are accurate compared with RR intervals derived from ECG. In this study we compared the accuracy of pulse intervals detected using an ambulatory blood pressure monitor (ABPM) with single lead ECG. Twenty participants wore an ABPM for three hours and a data logger which synchronously measured cuff pressure and ECG. RR intervals were compared with corresponding intervals derived from the cuff pressure tracings using three different pulse landmarks. Linear mixed effects models were used to assess differences between ECG and cuff pressure timings and to investigate the effect of potential covariates. In addition, the maximum number of successive oscillometric beats detectable in a measurement was assessed. From 243 BP measurements, the foot landmark of the oscillometric pulse was found to be associated with fewest covariates and had a random error of 9.5 ms. 99% of the cuff pressure recordings had more than 10 successive detectable oscillometric beats. RR intervals can be accurately estimated using an ABPM.


Kane, S. A., Blake, J. R., McArdle, F. J., Langley, P., & Sims, A. J. (2016). Accuracy of pulse interval timing in ambulatory blood pressure measurement. Scientific reports, 6(1), Article 37472.

Journal Article Type Article
Acceptance Date Oct 26, 2016
Online Publication Date Nov 23, 2016
Publication Date 2016-12
Deposit Date Nov 1, 2016
Publicly Available Date Nov 23, 2016
Journal Scientific reports
Print ISSN 2045-2322
Electronic ISSN 2045-2322
Publisher Nature Publishing Group
Peer Reviewed Peer Reviewed
Volume 6
Issue 1
Article Number 37472
Keywords Blood pressure measurement, Pulse interval timing
Public URL
Publisher URL
Additional Information This is a description of an article which has been accepted for future publication in: Scientific reports, 2016, v.6.


Article.pdf (840 Kb)

Copyright Statement
This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit

You might also like

Downloadable Citations