Studies on the sulfation of cellulose α-lipoate and ability of the sulfated product to stabilize colloidal suspensions of gold nanoparticles

Sarbova, Velina; Koschella, Andreas; Cheng, Fei; Kelly, Stephen M.; Heinze, Thomas

Abstract

© 2015 Elsevier Ltd. A versatile method for the synthesis of cellulose α-lipoate with a low degree of substitution (DS) has been developed using N,N-dimethylacetamide (DMA)/LiCl as a solvent and N,N′-carbonyldiimidazole (CDI) as an esterification reagent. The cellulose α-lipoate with DS of α-lipoate groups of 0.26 was converted with sulfur trioxide-pyridine complex in dimethyl sulfoxide (DMSO) as solvent. The sulfation is accompanied by an unexpected partial oxidation of the disulfide moiety leading to the formation of the corresponding stereoisomers of S-oxides. The resulting mixture of water-soluble cellulose α- and β-lipoate sulfate possesses a DS of sulfuric acid half ester groups of 1.78. This cellulose-α/β-lipoate sulfate derivative can be used as an effective stabilizer and solubilizer for the formation of colloidal suspensions of gold nanoparticles formed in situ in aqueous solution.

Citation

Sarbova, V., Koschella, A., Cheng, F., Kelly, S. M., & Heinze, T. (2015). Studies on the sulfation of cellulose α-lipoate and ability of the sulfated product to stabilize colloidal suspensions of gold nanoparticles. Carbohydrate Polymers, 124, 117-123. https://doi.org/10.1016/j.carbpol.2015.01.080

• Journal Article Type: Article
• Acceptance Date: Jan 25, 2015
• Online Publication Date: Feb 12, 2015
• Publication Date: Jun 25, 2015
• Deposit Date: May 12, 2016
• Publicly Available Date: May 12, 2016
• Journal: Carbohydrate polymers
• Print ISSN: 0144-8617
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 124
• Pages: 117-123
• DOI: https://doi.org/10.1016/j.carbpol.2015.01.080
• Keywords: Esterification of cellulose; Sulfur-containing cellulose derivatives; Water-solubility; Oxidation; Gold nanoparticles
• Public URL: https://hull-repository.worktribe.com/output/438000
• Publisher URL: http://www.sciencedirect.com/science/article/pii/S0144861715001174
• Additional Information: This is an authors accepted manuscript of an article published in Carbohydrate polymers, 2015, v.124.
• Contract Date: May 12, 2016