Dr Amin Ardestani A.Ardestani@hull.ac.uk
Senior Lecturer
How β cells can smell insulin fragments
Ardestani, Amin; Maedler, Kathrin
Authors
Kathrin Maedler
Abstract
In this issue of Cell Metabolism, Cheng et al. identify olfactory receptor Olfr109 in β cells with increased expression in islets from mouse models of obesity and type 1 and type 2 diabetes. Binding of a small insulin fragment to Olfr109 fosters islet inflammation, β cell failure, and diabetes progression.
Citation
Ardestani, A., & Maedler, K. (2022). How β cells can smell insulin fragments. Cell Metabolism, 34(2), 189-191. https://doi.org/10.1016/j.cmet.2022.01.003
| Journal Article Type | Note |
|---|---|
| Acceptance Date | Jan 16, 2022 |
| Online Publication Date | Feb 1, 2022 |
| Publication Date | Feb 1, 2022 |
| Deposit Date | Jan 3, 2024 |
| Journal | Cell metabolism |
| Print ISSN | 1550-4131 |
| Electronic ISSN | 1932-7420 |
| Publisher | Cell Press |
| Peer Reviewed | Peer Reviewed |
| Volume | 34 |
| Issue | 2 |
| Pages | 189-191 |
| DOI | https://doi.org/10.1016/j.cmet.2022.01.003 |
| Public URL | https://hull-repository.worktribe.com/output/4461482 |
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