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Time trends in neuropathology give clues to dementia risk reduction

Merrick, Richard; Matthews, Fiona E.

Authors

Richard Merrick



Abstract

A new study sheds light on the declining incidence of dementia by examining trends in neuropathology over time in autopsy results from two large US cohorts. Although the prevalence of neurodegenerative pathologies remained similar, a reduction in the prevalence of vascular pathologies over time suggests that improvements in both cardiovascular health and cognitive reserve have helped to reduce dementia risk.

Citation

Merrick, R., & Matthews, F. E. (2023). Time trends in neuropathology give clues to dementia risk reduction. Nature Reviews Neurology, 19(7), 389-390. https://doi.org/10.1038/s41582-023-00812-3

Journal Article Type Note
Acceptance Date Apr 8, 2023
Online Publication Date May 12, 2023
Publication Date Jul 1, 2023
Deposit Date Jan 21, 2024
Publicly Available Date Jan 29, 2024
Journal Nature Reviews Neurology
Print ISSN 1759-4758
Electronic ISSN 1759-4766
Publisher Nature Research
Peer Reviewed Peer Reviewed
Volume 19
Issue 7
Pages 389-390
DOI https://doi.org/10.1038/s41582-023-00812-3
Keywords Alzheimer's disease; Cerebrovascular disorders
Public URL https://hull-repository.worktribe.com/output/4496287

Files

Accepted manuscript (192 Kb)
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Copyright Statement
This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1038/s41582-023-00812-3





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