Genomic and phenotypic signatures of climate adaptation in an Anolis lizard

Rodríguez, Ariel; Rusciano, Tia; Hamilton, Rickeisha; Holmes, Leondra; Jordan, Deidra; Wollenberg Valero, Katharina C.

Abstract

Integrated knowledge on phenotype, physiology and genomic adaptations is required to understand the effects of climate on evolution. The functional genomic basis of organismal adaptation to changes in the abiotic environment, its phenotypic consequences, and its possible convergence across vertebrates, are still understudied. In this study, we use a comparative approach to verify predicted gene functions for vertebrate thermal adaptation with observed functions underlying repeated genomic adaptations in response to elevation in the lizard Anolis cybotes. We establish a direct link between recurrently evolved phenotypes and functional genomics of altitude-related climate adaptation in three highland and lowland populations in the Dominican Republic. We show that across vertebrates, genes contained in this interactome are expressed within the brain and during development. These results are relevant to elucidate the effect of global climate change across vertebrates, and might aid in furthering insight into gene-environment relationships under disturbances to external homeostasis.

Citation

Rodríguez, A., Rusciano, T., Hamilton, R., Holmes, L., Jordan, D., & Wollenberg Valero, K. C. (2017). Genomic and phenotypic signatures of climate adaptation in an Anolis lizard. Ecology and Evolution, 7(16), 6390-6403. https://doi.org/10.1002/ece3.2985

• Journal Article Type: Article
• Acceptance Date: Mar 21, 2017
• Online Publication Date: Jul 8, 2017
• Publication Date: Aug 29, 2017
• Deposit Date: May 30, 2017
• Publicly Available Date: Jul 8, 2017
• Journal: Ecology and evolution
• Electronic ISSN: 2045-7758
• Publisher: Wiley
• Peer Reviewed: Peer Reviewed
• Volume: 7
• Issue: 16
• Pages: 6390-6403
• DOI: https://doi.org/10.1002/ece3.2985
• Keywords: Anolis cybotes; Recurrence; Functional genomics; Population divergence; Thermal adaptation
• Public URL: https://hull-repository.worktribe.com/output/451751
• Publisher URL: http://onlinelibrary.wiley.com/doi/10.1002/ece3.2985/full
• Additional Information: Copy of article first published in: Ecology and evolution, 2017, v.7, issue 16.