Host-guest interaction of cucurbit[8]uril with n-(3-aminopropyl)cyclohexylamine: Cyclohexyl encapsulation triggered ternary complex

Xia, Yu; Wang, Chuan-Zeng; Tian, Mengkui; Tao, Zhu; Ni, Xin-Long; Prior, Timothy J.; Redshaw, Carl

Abstract

2018 by the authors. The host-guest interaction of a series of cyclohexyl-appended guests with cucurbit[8]uril (Q[8] ) was studied by 1 H NMR spectroscopy, isothermal titration calorimetry (ITC), and X-ray crystallography. The X-ray structure revealed that two cycloalkane moieties can be simultaneously encapsulated in the hydrophobic cavity of the Q[8] host to form a ternary complex for the first time.

Citation

Xia, Y., Wang, C., Tian, M., Tao, Z., Ni, X., Prior, T. J., & Redshaw, C. (2018). Host-guest interaction of cucurbit[8]uril with n-(3-aminopropyl)cyclohexylamine: Cyclohexyl encapsulation triggered ternary complex. Molecules, 23(1), 175. https://doi.org/10.3390/molecules23010175

• Journal Article Type: Article
• Acceptance Date: Jan 10, 2018
• Online Publication Date: Jan 15, 2018
• Publication Date: Jan 15, 2018
• Deposit Date: Aug 21, 2018
• Publicly Available Date: Aug 22, 2018
• Journal: Molecules
• Electronic ISSN: 1420-3049
• Publisher: MDPI
• Peer Reviewed: Peer Reviewed
• Volume: 23
• Issue: 1
• Pages: 175
• DOI: https://doi.org/10.3390/molecules23010175
• Keywords: Cucurbit[8]uril; Cycloalkane groups; Host-guest interaction; Ternary complex; X-ray structure
• Public URL: https://hull-repository.worktribe.com/output/614489
• Publisher URL: http://www.mdpi.com/1420-3049/23/1/175/htm