Mark D. Tarn
Plastic scintillator-based microfluidic devices for miniaturized detection of Positron Emission Tomography radiopharmaceuticals
Tarn, Mark D.; K?z?lyer, Nuray Yavuzkanat; Esfahani, Mohammad M. N.; Joshi, Pankaj; Brown, Nathaniel J.; Pamme, Nicole; Jenkins, David G.; Archibald, Stephen J.
Authors
Nuray Yavuzkanat K?z?lyer
Mohammad M. N. Esfahani
Pankaj Joshi
Nathaniel J. Brown
Nicole Pamme
David G. Jenkins
Professor Steve Archibald S.J.Archibald@hull.ac.uk
Professor in Molecular Imaging
Abstract
A miniaturized radio-HPLC detector has been developed comprising a microfluidic device fabricated from plastic scintillator in combination with a silicon photomultiplier light sensor, and tested with samples containing a positron-emitting radionuclide [18F]fluoride. This cost-effective, small footprint analytical tool is ideal for incorporation into integrated quality control systems for the testing of positron emission tomography (PET) radiopharmaceuticals to good manufacturing practice (GMP) standards.
Citation
Tarn, M. D., Kızılyer, N. Y., Esfahani, M. M. N., Joshi, P., Brown, N. J., Pamme, N., Jenkins, D. G., & Archibald, S. J. (2018). Plastic scintillator-based microfluidic devices for miniaturized detection of Positron Emission Tomography radiopharmaceuticals. Chemistry: a European journal, 24(52), 13749-13753. https://doi.org/10.1002/chem.201802395
Journal Article Type | Article |
---|---|
Acceptance Date | Jul 9, 2018 |
Online Publication Date | Jul 13, 2018 |
Publication Date | Sep 18, 2018 |
Deposit Date | Jul 12, 2018 |
Publicly Available Date | Jul 14, 2019 |
Print ISSN | 0947-6539 |
Publisher | Wiley |
Peer Reviewed | Peer Reviewed |
Volume | 24 |
Issue | 52 |
Pages | 13749-13753 |
DOI | https://doi.org/10.1002/chem.201802395 |
Keywords | Liquid chromatography; Microfluidics; Plastic scintillator; Positron emission tomography |
Public URL | https://hull-repository.worktribe.com/output/923614 |
Publisher URL | https://onlinelibrary.wiley.com/doi/full/10.1002/chem.201802395 |
Contract Date | Jul 12, 2018 |
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Copyright Statement
©2018 The authors
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