All Outputs (150)

Preparing for responsive management versus preparing for renal dialysis in multimorbid older people with advanced chronic kidney disease (Prepare for Kidney Care): Study protocol for a randomised controlled trial. (2024)
Journal Article
Worthington, J., Soundy, A., Frost, J., Rooshenas, L., MacNeill, S. J., Realpe Rojas, A., Garfield, K., Liu, Y., Alloway, K., Ben-Shlomo, Y., Burns, A., Chilcot, J., Darling, J., Davies, S., Farrington, K., Gibson, A., Husbands, S., Huxtable, R., McNally, H., Murphy, E., …Caskey, F. J. (2024). Preparing for responsive management versus preparing for renal dialysis in multimorbid older people with advanced chronic kidney disease (Prepare for Kidney Care): Study protocol for a randomised controlled trial. Trials, 25(1), Article 688. https://doi.org/10.1186/s13063-024-08509-8

Background: Chronic kidney disease (CKD) prevalence is steadily increasing, in part due to increased multimorbidity in our aging global population. When progression to kidney failure cannot be avoided, people need unbiased information to inform decis... Read More about Preparing for responsive management versus preparing for renal dialysis in multimorbid older people with advanced chronic kidney disease (Prepare for Kidney Care): Study protocol for a randomised controlled trial..

Implementing palliative care in the intensive care unit: a systematic review and mapping of knowledge to the implementation research logic model (2024)
Journal Article
Meddick‐Dyson, S. A., Boland, J. W., Pearson, M., Greenley, S., Gambe, R., Budding, J. R., & Murtagh, F. E. (online). Implementing palliative care in the intensive care unit: a systematic review and mapping of knowledge to the implementation research logic model. Intensive care medicine, https://doi.org/10.1007/s00134-024-07623-0

Purpose: The importance and effectiveness of palliative care (PC) in intensive care units (ICU) are known. Less is known about the implementation and integration of ICU-based PC interventions. This systematic review aims to use a modified implementat... Read More about Implementing palliative care in the intensive care unit: a systematic review and mapping of knowledge to the implementation research logic model.

Better End of Life 2024. Time to care: Findings from a nationally representative survey of experiences at the end of life in England and Wales (2024)
Report
Johansson, T., Pask, S., Goodrich, J., Budd, L., Okamoto, I., Kumar, R., Laidlaw, L., Ghiglieri, C., Woodhead, A., Chambers, R. L., Davies, J., Bone, A. E., Higginson, I. J., Barclay, S., Murtagh, F. E. M., & Sleeman, K. E. (2024). Better End of Life 2024. Time to care: Findings from a nationally representative survey of experiences at the end of life in England and Wales. Marie Curie

Foreword
This is a critical time for action to improve palliative and end of life care.

The findings from this nationally representative survey in England and Wales demonstrate the extent to which people are dying without access to the services... Read More about Better End of Life 2024. Time to care: Findings from a nationally representative survey of experiences at the end of life in England and Wales.

Benefits of specialist palliative care by identifying active ingredients of service composition, structure, and delivery model: A systematic review with meta-analysis and meta-regression (2024)
Journal Article
Johnson, M. J., Rutterford, L., Sunny, A., Pask, S., de Wolf-Linder, S., Murtagh, F. E., & Ramsenthaler, C. (2024). Benefits of specialist palliative care by identifying active ingredients of service composition, structure, and delivery model: A systematic review with meta-analysis and meta-regression. PLoS Medicine, 21(8), Article e1004436. https://doi.org/10.1371/journal.pmed.1004436

Background AU Specialist: Pleaseconfirmthatallheadinglevelsarerepresentedcorrectly palliative care (SPC) services address the needs :of people with advanced illness. Meta-analyses to date have been challenged by heterogeneity in SPC service models an... Read More about Benefits of specialist palliative care by identifying active ingredients of service composition, structure, and delivery model: A systematic review with meta-analysis and meta-regression.

Development of a Resource for Health Professionals to Raise Advance Care Planning Topics During Kidney Care Consultations: A Multiple User-Centered Design (2024)
Journal Article
Winterbottom, A., Hurst, H., Murtagh, F. E., Bekker, H. L., Ormandy, P., Hole, B., Russon, L., Murphy, E., Bucknall, K., & Mooney, A. (2024). Development of a Resource for Health Professionals to Raise Advance Care Planning Topics During Kidney Care Consultations: A Multiple User-Centered Design. Kidney Medicine, 6(9), Article 100874. https://doi.org/10.1016/j.xkme.2024.100874

Rationale & Objective: Planning and delivering treatment pathways that integrate end-of-life care, frailty assessment, and enhanced supportive care is a service priority. Despite this, people with kidney failure are less likely to have an advance car... Read More about Development of a Resource for Health Professionals to Raise Advance Care Planning Topics During Kidney Care Consultations: A Multiple User-Centered Design.

Association between ethnicity and emergency department visits in the last three months of life in England: a retrospective population-based study using electronic health records (2024)
Journal Article
Davies, J. M., Leniz, J., Chua, K.-C., Williamson, L. E., Bajwah, S., Bolton, T., Bone, A. E., Hocaoglu, M., Verne, J., Fraser, L. K., Barclay, S., Murtagh, F. E. M., Higginson, I. J., & Sleeman, K. E. (2024). Association between ethnicity and emergency department visits in the last three months of life in England: a retrospective population-based study using electronic health records. BMJ Public Health, 2(2), Article e001121. https://doi.org/10.1136/bmjph-2024-001121

Introduction Emergency department (ED) visits are distressing yet common in the last months of life and many could be avoided. The association between ethnicity and ED visits in the last months of life has rarely been studied in detail and the inters... Read More about Association between ethnicity and emergency department visits in the last three months of life in England: a retrospective population-based study using electronic health records.

Palliative Care in Kidney Disease (2024)
Book Chapter
Murphy, E., & Murtagh, F. E. M. (2024). Palliative Care in Kidney Disease. In R. MacLeod, & L. Van den Block (Eds.), Textbook of palliative care (1-20). Springer. https://doi.org/10.1007/978-3-319-31738-0_131-1

Understanding and addressing symptoms for those with kidney failure managed conservatively, without dialysis: considerations and models of care (2024)
Journal Article
Murphy, E., & Murtagh, F. E. M. (2024). Understanding and addressing symptoms for those with kidney failure managed conservatively, without dialysis: considerations and models of care. Annals of palliative medicine, 13(4), 991-1001. https://doi.org/10.21037/apm-23-422

For those who have kidney failure and are managed conservatively without dialysis, symptoms are often prevalent, multiple, and troublesome. They interfere with quality of life, reduce wellbeing, and can affect family carers too. Symptoms can sometime... Read More about Understanding and addressing symptoms for those with kidney failure managed conservatively, without dialysis: considerations and models of care.

Patterns of acute hospital and specialist palliative care use among people with non-curative upper gastrointestinal cancer (2024)
Journal Article
Boland, E. G., Tay, K. T., Khamis, A., & Murtagh, F. E. (2024). Patterns of acute hospital and specialist palliative care use among people with non-curative upper gastrointestinal cancer. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 32(7), Article 432. https://doi.org/10.1007/s00520-024-08624-x

Purpose: Upper gastrointestinal (GI) cancers contribute to 16.7% of UK cancer deaths. These patients make high use of acute hospital services, but detail about palliative care use is lacking. We aimed to determine the patterns of use of acute hospita... Read More about Patterns of acute hospital and specialist palliative care use among people with non-curative upper gastrointestinal cancer.

What are the anticipated benefits, risks, barriers and facilitators to implementing person-centred outcome measures into routine care for children and young people with life-limiting and life-threatening conditions? A qualitative interview study with key stakeholders (2024)
Journal Article
May Scott, H. M., Coombes, L., Braybrook, D., Harðardóttir, D., Roach, A., Bristowe, K., …On Behalf Of C-POS. (2024). What are the anticipated benefits, risks, barriers and facilitators to implementing person-centred outcome measures into routine care for children and young people with life-limiting and life-threatening conditions? A qualitative interview study with key stakeholders. Palliative medicine, 38(4), 471-484. https://doi.org/10.1177/02692163241234797

Background: There is a growing evidence-base underpinning implementation of person-centred outcome measures into adult palliative care. However evidence on how best to achieve this with children facing life-threatening and life-limiting conditions is... Read More about What are the anticipated benefits, risks, barriers and facilitators to implementing person-centred outcome measures into routine care for children and young people with life-limiting and life-threatening conditions? A qualitative interview study with key stakeholders.

Creating more comparable cohorts in observational palliative care studies: A proposed framework to improve applicability and replicability of research (2024)
Journal Article
Kochovska, S., Murtagh, F. E., Agar, M., Phillips, J. L., Dudgeon, D., Lujic, S., Johnson, M., & Currow, D. C. (2024). Creating more comparable cohorts in observational palliative care studies: A proposed framework to improve applicability and replicability of research. Palliative medicine, https://doi.org/10.1177/02692163241234227

Background: Palliative care is characterised by heterogeneous patient and caregiver populations who are provided care in different health systems and a research base including a large proportion of observational, mostly retrospective studies. The inh... Read More about Creating more comparable cohorts in observational palliative care studies: A proposed framework to improve applicability and replicability of research.

‘My life is a mess but I cope’: An analysis of the language children and young people use to describe their own life-limiting or life-threatening condition (2024)
Journal Article
Bristowe, K., Braybrook, D., Scott, H. M., Coombes, L., Harðardóttir, D., Roach, A., …Harding, R. (2024). ‘My life is a mess but I cope’: An analysis of the language children and young people use to describe their own life-limiting or life-threatening condition. Palliative medicine, https://doi.org/10.1177/02692163241233977

Background: Children and young people with life-limiting and life-threatening conditions have multidimensional needs and heterogenous cognitive and communicative abilities. There is limited evidence to support clinicians to tailor their communication... Read More about ‘My life is a mess but I cope’: An analysis of the language children and young people use to describe their own life-limiting or life-threatening condition.

Understanding patient and family utilisation of community-based palliative care services out-of-hours: Additional analysis of systematic review evidence using narrative synthesis (2024)
Journal Article
Goodrich, J., Watson, C., Gaczkowska, I., Harding, R., Evans, C., Firth, A., & Murtagh, F. E. (2024). Understanding patient and family utilisation of community-based palliative care services out-of-hours: Additional analysis of systematic review evidence using narrative synthesis. PLoS ONE, 19(2 FEBRUARY), Article e0296405. https://doi.org/10.1371/journal.pone.0296405

Background Community-based out-of-hours services are an integral component of end-of-life care. However, there is little understanding of how patients and families utilise these services. This additional analysis of a systematic review aims to unders... Read More about Understanding patient and family utilisation of community-based palliative care services out-of-hours: Additional analysis of systematic review evidence using narrative synthesis.

Exploring pathways to optimise care in malignant bowel obstruction (EPOC): Protocol for a three-phase critical realist approach to theory-led intervention development for shared decision-making (2024)
Journal Article
Bravington, A., Boland, J. W., Greenley, S., Lind, M., Murtagh, F. E., Patterson, M., Pearson, M., & Johnson, M. J. (2024). Exploring pathways to optimise care in malignant bowel obstruction (EPOC): Protocol for a three-phase critical realist approach to theory-led intervention development for shared decision-making. PLoS ONE, 19(1 January), Article e0294218. https://doi.org/10.1371/journal.pone.0294218

Introduction Malignant bowel obstruction is a distressing complication of cancer, causing pain, nausea and vomiting, and often has a poor prognosis. Severe and rapidly developing symptoms, a lack of robust clinical guidelines and the need for multidi... Read More about Exploring pathways to optimise care in malignant bowel obstruction (EPOC): Protocol for a three-phase critical realist approach to theory-led intervention development for shared decision-making.

Advance care planning for patients with end-stage kidney disease on dialysis: narrative review of the current evidence, and future considerations (2024)
Journal Article
Adenwalla, S. F., O’Halloran, P., Faull, C., Murtagh, F. E., & Graham-Brown, M. P. (2024). Advance care planning for patients with end-stage kidney disease on dialysis: narrative review of the current evidence, and future considerations. Journal of Nephrology, 37(3), 547-560. https://doi.org/10.1007/s40620-023-01841-3

Patients with end-stage kidney disease (ESKD) have a high symptom-burden and high rates of morbidity and mortality. Despite this, evidence has shown that this patient group does not have timely discussions to plan for deterioration and death, and at... Read More about Advance care planning for patients with end-stage kidney disease on dialysis: narrative review of the current evidence, and future considerations.

Telephone advice lines for adults with advanced illness and their family carers: a qualitative analysis and novel practical framework (2024)
Journal Article
Pask, S., Omoruyi, A., Mohamed, A., Chambers, R. L., McFarlane, P. G., Johansson, T., …Murtagh, F. E. (2024). Telephone advice lines for adults with advanced illness and their family carers: a qualitative analysis and novel practical framework. Palliative medicine, https://doi.org/10.1177/02692163241242329

Background: Telephone advice lines have been recommended internationally to support around-the-clock care for people living at home with advanced illness. While they undoubtedly support care, there is little evidence about what elements are needed fo... Read More about Telephone advice lines for adults with advanced illness and their family carers: a qualitative analysis and novel practical framework.

A casemix classification for those receiving specialist palliative care during their last year of life across England: the C-CHANGE research programme (2023)
Journal Article
Murtagh, F. E., Guo, P., Firth, A., Yip, K. M., Ramsenthaler, C., Douiri, A., …Higginson, I. J. (2023). A casemix classification for those receiving specialist palliative care during their last year of life across England: the C-CHANGE research programme. Programme Grants for Applied Research, 11(7), https://doi.org/10.3310/plrp4875

Abstract
Background
The hospice movement has provided an excellent model of specialist palliative care for those with advanced illness approaching the end of life. However, there are marked inequities in provision of this care, and major geographic... Read More about A casemix classification for those receiving specialist palliative care during their last year of life across England: the C-CHANGE research programme.

Implementation lessons learnt when evaluating palliative care interventions in the intensive care unit: relationships between implementation determinants, strategies, and models of delivery (2023)
Thesis
Meddick-Dyson, S. Implementation lessons learnt when evaluating palliative care interventions in the intensive care unit: relationships between implementation determinants, strategies, and models of delivery. (Thesis). Hull York Medical School. https://hull-repository.worktribe.com/output/4587991

Background
Palliative and end-of-life care have important roles in intensive care units (ICUs) given symptom burden and rate of mortality in ICUs. However, we do not know how ICU-based palliative care interventions should be implemented. This system... Read More about Implementation lessons learnt when evaluating palliative care interventions in the intensive care unit: relationships between implementation determinants, strategies, and models of delivery.

Implementing patient-centred outcome measures in palliative care clinical practice for adults (IMPCOM): Protocol for an update systematic review of facilitators and barriers (2023)
Journal Article
Antunes, B., Barclay, S., Kuhn, I., Eagar, K., Bausewein, C., Murtagh, F., …Shokraneh, F. (2023). Implementing patient-centred outcome measures in palliative care clinical practice for adults (IMPCOM): Protocol for an update systematic review of facilitators and barriers. F1000Research, 12, Article 224. https://doi.org/10.12688/f1000research.131479.2

Background: Despite the development of patient-centred or patient-reported outcome measures (PCOMs or PROMs) in palliative and end-of-life care over recent years, their routine use in practice faces continuing challenges. Objective: To update a highl... Read More about Implementing patient-centred outcome measures in palliative care clinical practice for adults (IMPCOM): Protocol for an update systematic review of facilitators and barriers.

Development of a Core Outcome Set for the research and assessment of malignant bowel obstruction (2023)
Journal Article
Bravington, A., Obita, G., Baddeley, E., Johnson, M., Murtagh, F., Currow, D., …Boland, J. (2023). Development of a Core Outcome Set for the research and assessment of malignant bowel obstruction. PLoS ONE, 18(8), Article e0289501. https://doi.org/10.1371/journal.pone.0289501

Background: Malignant bowel obstruction is experienced by 15% of people with advanced cancer, preventing them from eating and drinking and causing pain, nausea and vomiting. Surgery is not always appropriate. Management options include tube or stent... Read More about Development of a Core Outcome Set for the research and assessment of malignant bowel obstruction.