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All Outputs (160)

Disease-related factors affecting timely lymphoma diagnosis: A qualitative study exploring patient experiences (2019)
Journal Article
Howell, D. A., Hart, R. I., Smith, A. G., Roman, E., Macleod, U., & Patmore, R. (2019). Disease-related factors affecting timely lymphoma diagnosis: A qualitative study exploring patient experiences. The British journal of general practice : the journal of the Royal College of General Practitioners, 69(679), E134-E145. https://doi.org/10.3399/bjgp19X701009

© British Journal of General Practice. Background Expediting cancer diagnosis is widely perceived as one way to improve patient outcomes. Evidence indicates that lymphoma diagnosis is often delayed, yet understanding of issues influencing this is inc... Read More about Disease-related factors affecting timely lymphoma diagnosis: A qualitative study exploring patient experiences.

Lung cancer symptom appraisal among people with chronic obstructive pulmonary disease: A qualitative interview study (2019)
Journal Article
Cunningham, Y., Wyke, S., Blyth, K. G., Rigg, D., Macdonald, S., Macleod, U., Harrow, S., Robb, K. A., & Whitaker, K. L. (2019). Lung cancer symptom appraisal among people with chronic obstructive pulmonary disease: A qualitative interview study. Psycho-oncology, 28(4), 718-725. https://doi.org/10.1002/pon.5005

© 2019 The Authors. Psycho-Oncology Published by John Wiley & Sons Ltd. Objective: The incidence of lung cancer is four times higher in people with chronic obstructive pulmonary disease (COPD) compared with the general population. Promotion of a sh... Read More about Lung cancer symptom appraisal among people with chronic obstructive pulmonary disease: A qualitative interview study.

Time intervals from first symptom to diagnosis for head and neck cancers: An analysis of linked patient reports and medical records from the UK (2019)
Journal Article
Allgar, V. L., Oliver, S. E., Chen, H., Oviasu, O., Johnson, M. J., & Macleod, U. (2019). Time intervals from first symptom to diagnosis for head and neck cancers: An analysis of linked patient reports and medical records from the UK. Cancer epidemiology, 59, 37-45. https://doi.org/10.1016/j.canep.2019.01.008

© 2019 Elsevier Ltd Background: England has significantly higher mortality risks due to Head and Neck Cancer (HNC) compared with other European countries. Early diagnosis is important as it is likely to increase early-stage diagnosis and improve surv... Read More about Time intervals from first symptom to diagnosis for head and neck cancers: An analysis of linked patient reports and medical records from the UK.

Making sense of bodily sensations: Do shared cancer narratives influence symptom appraisal? (2019)
Journal Article
Macdonald, S., Conway, E., Bikker, A., Browne, S., Robb, K., Campbell, C., Steele, R. J., Weller, D., & Macleod, U. (2019). Making sense of bodily sensations: Do shared cancer narratives influence symptom appraisal?. Social science & medicine, 223, 31-39. https://doi.org/10.1016/j.socscimed.2018.12.034

© 2019 Elsevier Ltd Though new or altered bodily sensations are a common occurrence they rarely transition to biomedically defined symptoms. When they do, sensations are subject to an appraisal process that can culminate in help-seeking. The transiti... Read More about Making sense of bodily sensations: Do shared cancer narratives influence symptom appraisal?.

Identifying potentially inappropriate prescribing in older people with dementia: a systematic review (2019)
Journal Article
Hukins, D., Macleod, U., & Boland, J. W. (2019). Identifying potentially inappropriate prescribing in older people with dementia: a systematic review. European Journal of Clinical Pharmacology, 75(4), 467-481. https://doi.org/10.1007/s00228-018-02612-x

Purpose: Older people with dementia are at risk of adverse events associated with potentially inappropriate prescribing. Aim: to describe (1) how international tools designed to identify potentially inappropriate prescribing have been used in studies... Read More about Identifying potentially inappropriate prescribing in older people with dementia: a systematic review.

Safety netting for primary care: Evidence from a literature review (2019)
Journal Article
Jones, D., Dunn, L., Watt, I., & Macleod, U. (2019). Safety netting for primary care: Evidence from a literature review. The British journal of general practice : the journal of the Royal College of General Practitioners, 69(678), E70-E79. https://doi.org/10.3399/bjgp18X700193

© British Journal of General Practice.
Background: Ensuring patient safety is vital in primary care. One mechanism to increase patient safety is through a practice known as safety netting. Safety netting is widely recommended in national guidelines;... Read More about Safety netting for primary care: Evidence from a literature review.

Rapid review of factors associated with flexible sigmoidoscopy screening use (2018)
Journal Article
Kerrison, R. S., von Wagner, C., Green, T., Gibbins, M., Macleod, U., Hughes, M., Rees, C. J., Duffy, S., & McGregor, L. M. (2019). Rapid review of factors associated with flexible sigmoidoscopy screening use. Preventive Medicine, 120, 8-18. https://doi.org/10.1016/j.ypmed.2018.12.018

© 2019 The Authors Flexible sigmoidoscopy (FS) screening has been shown to reduce colorectal cancer (CRC) incidence and mortality among screened adults. The aim of this review was to identify patient-related factors associated with the screening test... Read More about Rapid review of factors associated with flexible sigmoidoscopy screening use.

Combining mirtazapine with SSRIs or SNRIs for treatment-resistant depression: The MIR RCT (2018)
Journal Article
Kessler, D., Burns, A., Tallon, D., Lewis, G., Macneill, S., Round, J., Hollingworth, W., Chew-Graham, C., Anderson, I., Campbell, J., Dickens, C., Macleod, U., Gilbody, S., Davies, S., Peters, T. J., & Wiles, N. (2018). Combining mirtazapine with SSRIs or SNRIs for treatment-resistant depression: The MIR RCT. Health Technology Assessment, 22(63), 1-136. https://doi.org/10.3310/hta22630

Background: Depression is usually managed in primary care and antidepressants are often the first-line treatment, but only half of those treated respond to a single antidepressant.
Objectives: To investigate whether or not combining mirtazapine wit... Read More about Combining mirtazapine with SSRIs or SNRIs for treatment-resistant depression: The MIR RCT.

Mirtazapine added to SSRIs or SNRIs for treatment resistant depression in primary care: Phase III randomised placebo controlled trial (MIR) (2018)
Journal Article
Kessler, D. S., MacNeill, S. J., Tallon, D., Lewis, G., Peters, T. J., Hollingworth, W., Round, J., Burns, A., Chew-Graham, C. A., Anderson, I. M., Shepherd, T., Campbell, J., Dickens, C. M., Carter, M., Jenkinson, C., Macleod, U., Gibson, H., Davies, S., & Wiles, N. J. (2018). Mirtazapine added to SSRIs or SNRIs for treatment resistant depression in primary care: Phase III randomised placebo controlled trial (MIR). BMJ, 363, Article k4218. https://doi.org/10.1136/bmj.k4218

Objective: To investigate the effectiveness of combining mirtazapine with Serotonin-Noradrenaline Reuptake Inhibitor (SNRI) or Selective Serotonin Reuptake Inhibitor (SSRI) antidepressants for patients in primary care who had not responded to an anti... Read More about Mirtazapine added to SSRIs or SNRIs for treatment resistant depression in primary care: Phase III randomised placebo controlled trial (MIR).

Overcoming difficulties with equipoise to enable recruitment to a randomised controlled trial of partial ablation vs radical prostatectomy for unilateral localised prostate cancer (2018)
Journal Article
Elliott, D., Hamdy, F. C., Leslie, T. A., Rosario, D., Dudderidge, T., Hindley, R., …Donovan, J. L. (2018). Overcoming difficulties with equipoise to enable recruitment to a randomised controlled trial of partial ablation vs radical prostatectomy for unilateral localised prostate cancer. BJU international, 122(6), 970-977. https://doi.org/10.1111/bju.14432

Abstract
Objective
To describe how clinicians conceptualised equipoise in the PART (Partial prostate Ablation vs Radical prosTatectomy in intermediate‐risk unilateral clinically localised prostate cancer) feasibility study and how this affected rec... Read More about Overcoming difficulties with equipoise to enable recruitment to a randomised controlled trial of partial ablation vs radical prostatectomy for unilateral localised prostate cancer.

Primary care redesign for person-centred care: Delivering an international generalist revolution (2018)
Journal Article
Reeve, J. (2018). Primary care redesign for person-centred care: Delivering an international generalist revolution. Australian journal of primary health, 24(4), 330-336. https://doi.org/10.1071/py18019

© La Trobe University. Person-centred primary care is a priority for patients, healthcare practitioners and health policy. Despite this, data suggest person-centred care is still not consistently achieved-and indeed, that in some areas, care may be w... Read More about Primary care redesign for person-centred care: Delivering an international generalist revolution.

Psychometric Properties of the Needs Assessment Tool—Progressive Disease Cancer in U.K. Primary Care (2018)
Journal Article
Allgar, V. L., Chen, H., Richfield, E., Currow, D., Macleod, U., & Johnson, M. J. (2018). Psychometric Properties of the Needs Assessment Tool—Progressive Disease Cancer in U.K. Primary Care. Journal of pain and symptom management, 56(4), 602-612. https://doi.org/10.1016/j.jpainsymman.2018.07.002

Background. The assessment of patients' needs for care is a critical step in achieving patient-centered cancer care. Tools can be used to assess needs and inform care planning. The Needs Assessment Tool:Progressive DiseaseeCancer (NAT:PD-C) is an Aus... Read More about Psychometric Properties of the Needs Assessment Tool—Progressive Disease Cancer in U.K. Primary Care.

Using primary care-based paper and telephone interventions to increase uptake of bowel scope screening in Yorkshire: A protocol of a randomised controlled trial (2018)
Journal Article
McGregor, L. M., Kerrison, R. S., Green, T., MacLeod, U., Hughes, M., Gibbins, M., Morris, S., Rees, C., & Von Wagner, C. (2018). Using primary care-based paper and telephone interventions to increase uptake of bowel scope screening in Yorkshire: A protocol of a randomised controlled trial. BMJ open, 8(7), Article e024616. https://doi.org/10.1136/bmjopen-2018-024616

© Author(s) (or their employer(s)) 2018. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. Introduction Evidence suggests bowel scope screening (BSS) can significantly reduce an individual's risk of... Read More about Using primary care-based paper and telephone interventions to increase uptake of bowel scope screening in Yorkshire: A protocol of a randomised controlled trial.

Emergency admissions and subsequent inpatient care through an emergency oncology service at a tertiary cancer centre: service users’ experiences and views (2018)
Journal Article
Chen, H., Johnson, M., Boland, E., Seymour, J., & Macleod, U. (2019). Emergency admissions and subsequent inpatient care through an emergency oncology service at a tertiary cancer centre: service users’ experiences and views. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 27(2), 451–460. https://doi.org/10.1007/s00520-018-4328-5

Purpose Avoiding unnecessary emergency admissions and managing those that are admitted more effectively is a major concern for both patients and health services. To generate evidence useful for improving services for direct patient benefit, this stu... Read More about Emergency admissions and subsequent inpatient care through an emergency oncology service at a tertiary cancer centre: service users’ experiences and views.

The diagnostic test accuracy of rectal examination for prostate cancer diagnosis in symptomatic patients: A systematic review (2018)
Journal Article
Jones, D., Friend, C., Dreher, A., Allgar, V., & Macleod, U. (2018). The diagnostic test accuracy of rectal examination for prostate cancer diagnosis in symptomatic patients: A systematic review. BMC family practice, 19(1), Article 79. https://doi.org/10.1186/s12875-018-0765-y

© 2018 The Author(s). Background: Prostate cancer is the most common cancer in men in the UK. NICE guidelines on recognition and referral of suspected cancer, recommend performing digital rectal examination (DRE) on patients with urinary symptoms and... Read More about The diagnostic test accuracy of rectal examination for prostate cancer diagnosis in symptomatic patients: A systematic review.

Use of a GP-endorsed 12 months' reminder letter to promote uptake of bowel scope screening: Protocol for a randomised controlled trial in a hard-to-reach population (2018)
Journal Article
Von Wagner, C., Hirst, Y., Tookey, S., Kerrison, R. S., Marshall, S., Prentice, A., Vulkan, D., Macleod, U., & Duffy, S. (2018). Use of a GP-endorsed 12 months' reminder letter to promote uptake of bowel scope screening: Protocol for a randomised controlled trial in a hard-to-reach population. BMJ open, 8(5), Article e022263. https://doi.org/10.1136/bmjopen-2018-022263

Introduction: Flexible sigmoidoscopy (FS) screening is associated with reduced colorectal cancer incidence and mortality when offered as a one-off test to men and women aged 55-64. The test, also referred to as the 'bowel scope screening' (BSS) test,... Read More about Use of a GP-endorsed 12 months' reminder letter to promote uptake of bowel scope screening: Protocol for a randomised controlled trial in a hard-to-reach population.

Mass media and risk factors for cancer: the under-representation of age (2018)
Journal Article
Macdonald, S., Cunningham, Y., Patterson, C., Robb, K., Macleod, U., Anker, T., & Hilton, S. (2018). Mass media and risk factors for cancer: the under-representation of age. BMC public health, 18(1), Article 490. https://doi.org/10.1186/s12889-018-5341-9

BACKGROUND: Increasing age is a risk factor for developing cancer. Yet, older people commonly underestimate this risk, are less likely to be aware of the early symptoms, and are more likely to be diagnosed with advanced stage cancer. Mass media are a... Read More about Mass media and risk factors for cancer: the under-representation of age.

Myeloma: Patient accounts of their pathways to diagnosis (2018)
Journal Article
Howell, D. A., Hart, R. I., Smith, A. G., Macleod, U., Patmore, R., Cook, G., & Roman, E. (2018). Myeloma: Patient accounts of their pathways to diagnosis. PLoS ONE, 13(4), Article e0194788. https://doi.org/10.1371/journal.pone.0194788

© 2018 Howell et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are cre... Read More about Myeloma: Patient accounts of their pathways to diagnosis.