All Outputs (21)

Quantitative proteomics of pancreatic cyst fluid for early diagnosis of cancer. (2023)
Presentation / Conference Contribution
Nikitenko, L. L., Manolis, D., O'Brien, D. P., Adekeye, A., Kessler, B. M., Collins, C., Kramer, H., Chang, D., & Maraveyas, A. Quantitative proteomics of pancreatic cyst fluid for early diagnosis of cancer. Presented at The London Pancreas Workshop 2023, London, United Kingdom

In our EARLY DIAgnosis of PAncreatic Cancer (EARLY DIAPAC) study, we aim to analyse molecular changes or “signatures” associated with early stages of pancreatic carcinogenesis by using the combination of: (i) Label-Free Quantitative Proteomics (LFQP)... Read More about Quantitative proteomics of pancreatic cyst fluid for early diagnosis of cancer..

An age-associated reduction in Nav1.5 protein expression correlates with an increase in Nav1.8 protein expression in the right atrial appendage of the human heart. (2020)
Presentation / Conference Contribution
Isaac, E., Cooper, S., Lancaster, M., Loubani, M., & Jones, S. (2020). An age-associated reduction in Nav1.5 protein expression correlates with an increase in Nav1.8 protein expression in the right atrial appendage of the human heart. Circulation Research, 127(Suppl_1), A493

Background: Nav1.5 is the predominantly expressed voltage-gated sodium channel (VGSC) isoform in the heart, responsible for phase 0 of the action potential. Our rodent studies have shown expression of neuronal isoform Nav1.8 protein in the adult hear... Read More about An age-associated reduction in Nav1.5 protein expression correlates with an increase in Nav1.8 protein expression in the right atrial appendage of the human heart..

Conformational studies of tylosin A, tylosin B, erythromycin B and erythromycin C and full assignments of tylosin A in CDCl3 and tylosin B in phosphate buffered D2O (2017)
Presentation / Conference Contribution
Arsic, B., Regan, . A., Morris, G., Oates, A., McBain, . A., & Barber, J. (2017, June). Conformational studies of tylosin A, tylosin B, erythromycin B and erythromycin C and full assignments of tylosin A in CDCl3 and tylosin B in phosphate buffered D2O. Poster presented at 1st RSC Anglo-Nordic Medicinal Chemistry Symposium, Copenhagen, Denmark

Microfluidic culture of head and neck tumour maintains viability, as shown by single cell analysis, providing potential for novel applications and personalised medicine (2016)
Presentation / Conference Contribution
Bower, R., Green, V., Kuvshinov, D., Crank, S., Stafford, N., & Greenman, J. (2016). Microfluidic culture of head and neck tumour maintains viability, as shown by single cell analysis, providing potential for novel applications and personalised medicine.

The current paper details a succinct characterisation of an in-house designed microfluidic culture device. The maintenance of tissue viability was determined by studying single cells, following dissociation, of head and neck tumour pre and post cultu... Read More about Microfluidic culture of head and neck tumour maintains viability, as shown by single cell analysis, providing potential for novel applications and personalised medicine.

Anticancer properties of Thymbra capitata and Helichrysum italicum essential oils (2014)
Presentation / Conference Contribution
Juliana, P., Marco, L., Célia, C., Lígia, S., & Pires, I. M. D. S. (2014). Anticancer properties of Thymbra capitata and Helichrysum italicum essential oils. . https://doi.org/10.3389/conf.fmars.2014.02.00010

An essential oil (EO) is defined internationally as the product obtained by hydrodistillation, of a plant or some parts of it. They are aromatic oily liquids, volatile, characterized by a strong odour, rarely coloured, and generally with a lower dens... Read More about Anticancer properties of Thymbra capitata and Helichrysum italicum essential oils.

Assessment of the properties of the essential oil from Ridolfia segetum Moris (Portugal) on cancer cell viability (2014)
Presentation / Conference Contribution
Poças, J., Lemos, M., Cabral, C., Cavaleiro, C., Cruz, M., Salgueiro, L., & Pires, I. (2014). Assessment of the properties of the essential oil from Ridolfia segetum Moris (Portugal) on cancer cell viability. . https://doi.org/10.1055/s-0034-1394701

Ridolfia segetum Moris, commonly known as corn parsley, false fennel, or false caraway, is distributed throughout the Mediterranean region. It belongs to the Apiaceae (carrot or parsley family), which includes well-known aromatic and medicinal plants... Read More about Assessment of the properties of the essential oil from Ridolfia segetum Moris (Portugal) on cancer cell viability.

Abstract P2-02-03: the collagen receptor Endo180: a metastatic plasma marker in breast cancer modulated by bisphosphonate treatment (2012)
Presentation / Conference Contribution
Sturge, J., Caley, M., Purshouse, K., Fonseca, A., Rodriguez-Teja, M., Kogianni, G., …Palmieri, C. (2012). Abstract P2-02-03: the collagen receptor Endo180: a metastatic plasma marker in breast cancer modulated by bisphosphonate treatment. Cancer Research, 72(24 suppl), https://doi.org/10.1158/0008-5472.sabcs12-p2-02-03

Sphingosine kinase-1 and the collagen-binding receptor Endo180 cooperate to mediate collagen remodelling by stromal fibroblasts (2010)
Presentation / Conference Contribution
Bruche, S., Caley, M., Pshezhetskiy, D., & Sturge, J. (2010). Sphingosine kinase-1 and the collagen-binding receptor Endo180 cooperate to mediate collagen remodelling by stromal fibroblasts. International Journal of Experimental Pathology, 91(6), A9

Macrophage-mediated breast cancer cell chemotaxis: the role of sphingosine kinase-1 activation (2010)
Presentation / Conference Contribution
Nunes, J., Sauer, L., Turner, J., Waxman, J., Sturge, J., & Pshezhetskiy, D. (2010). Macrophage-mediated breast cancer cell chemotaxis: the role of sphingosine kinase-1 activation. Breast Cancer Research, 12(S1), S6-S6. https://doi.org/10.1186/bcr2513

Collagen remodelling by osteoblast and prostate vancer vell interactions in metastatic bone lesions (2009)
Presentation / Conference Contribution
Sturge, J. (2009). Collagen remodelling by osteoblast and prostate vancer vell interactions in metastatic bone lesions.

A major clinical complication in patients with advanced prostate cancer is metastasis to bone where osteoblastic and/or osteoclastic activity results in a highly destructive tissue remodelling process.Recent in vivo studies have identified important... Read More about Collagen remodelling by osteoblast and prostate vancer vell interactions in metastatic bone lesions.

The role of endo180 in the development of metastatic prostate cancer bone lesions (2008)
Presentation / Conference Contribution
Kogianni, G., Elefteriou, K., Waxman, . J., Cobb, . J. P., & Sturge, J. (2008). The role of endo180 in the development of metastatic prostate cancer bone lesions. Anticancer research, 28(5C), 3354-3355

Endo180 expression by tumour cells with an invasive phenotype correlates with prostate cancer progression (2008)
Presentation / Conference Contribution
Kogianni, G., Walker, M., Waxman, J., & Sturge, J. (2008). Endo180 expression by tumour cells with an invasive phenotype correlates with prostate cancer progression. EJC Supplements, 6(9), 79. https://doi.org/10.1016/s1359-6349%2808%2971480-0

OC6. Endo180 function in metastatic prostate cancer bone lesions (2008)
Presentation / Conference Contribution
Kogianni, G., Eleftheriou, K., Waxman, J., Cobb, J. P., & Sturge, J. (2008). OC6. Endo180 function in metastatic prostate cancer bone lesions. Cancer Treatment Reviews, 34(Suppl 1), 51. https://doi.org/10.1016/j.ctrv.2008.03.032

Differential activation of MAPK pathways in human coronary artery smooth muscle cells and endothelial cells in response to exogenous tissue factor (2005)
Presentation / Conference Contribution
Wood, C., Chetter, I., McCollum, P., & Ettelaie, C. (2005). Differential activation of MAPK pathways in human coronary artery smooth muscle cells and endothelial cells in response to exogenous tissue factor. Journal of vascular research, 42(supp.2), 93 - 93

Differential influence of tissue factor on the activation of mapk pathway in human coronary artery smooth muscle cells (2005)
Presentation / Conference Contribution
Wood, C., McCollum, P., Chetter, I., & Ettelaie, C. (2005). Differential influence of tissue factor on the activation of mapk pathway in human coronary artery smooth muscle cells. Journal of Molecular and Cellular Cardiology, 38(6), 1082 - 1082

Plasma tissue factor, a predictor for restenosis following percutaneous transluminal angioplasty (2005)
Presentation / Conference Contribution
Ray, B., Ettles, D., Lee, D., Robinson, G., Bryce, J., Mylankal, K., …Ettelaie, C. (2005). Plasma tissue factor, a predictor for restenosis following percutaneous transluminal angioplasty. British journal of surgery, 92(4), 502 - 502. https://doi.org/10.1002/bjs.5038

Expression of cellular mediators in response to oxidative and hypoxic stress: role for statins? (2004)
Presentation / Conference Contribution
Ray, B., Mylankal, K., McCollum, P., Chetter, I., & Ettelaie, C. (2004). Expression of cellular mediators in response to oxidative and hypoxic stress: role for statins?. British journal of surgery, 91(S1), 112 - 113. https://doi.org/10.1002/bjs.4681

Statins offer a protective role against oxidative and hypoxic stress induced vascular endothelial apoptosis (2003)
Presentation / Conference Contribution
Ray, B., Mylankal, K., McCollum, P., Chetter, I., & Ettelaie, C. (2003). Statins offer a protective role against oxidative and hypoxic stress induced vascular endothelial apoptosis. Atherosclerosis, 170(1), S13 - S13

Hyperbaric oxygen restores the antioxidant defence mechansim following exercise in patients with intermittent claudication (2001)
Presentation / Conference Contribution
Abidia, A., Kuhan, G., Laden, G., Bahia, H., Chetter, I., Greenman, J., & McCollum, P. (2001). Hyperbaric oxygen restores the antioxidant defence mechansim following exercise in patients with intermittent claudication. Undersea and Hyperbaric Medical Society meeting abstracts, 28(32), 0 - 0

BACKGROUND: Intermittent claudication represents a minor ischaemia reperfusion episode. Exposure to hyperbaric oxygen during such episodes is a concern to many vascular surgeons because of the theoretical risk of generating excess free radicals. We a... Read More about Hyperbaric oxygen restores the antioxidant defence mechansim following exercise in patients with intermittent claudication.

Calbindin-D(9κ) protein and mRNA localisation in bovine placenta (1997)
Presentation / Conference Contribution
Nikitenko, L., Morgan, G., & Wooding, F. B. (1997). Calbindin-D(9κ) protein and mRNA localisation in bovine placenta. Journal of anatomy, 191(1), 143-144. https://doi.org/10.1046/j.1469-7580.1997.19110123.x