Skip to main content

Research Repository

Advanced Search

All Outputs (24)

Quantitative proteomics of pancreatic cyst fluid for early diagnosis of cancer. (2023)
Presentation / Conference Contribution
Nikitenko, L. L., Manolis, D., O'Brien, D. P., Adekeye, A., Kessler, B. M., Collins, C., Kramer, H., Chang, D., & Maraveyas, A. Quantitative proteomics of pancreatic cyst fluid for early diagnosis of cancer. Presented at The London Pancreas Workshop 2023, London, United Kingdom

In our EARLY DIAgnosis of PAncreatic Cancer (EARLY DIAPAC) study, we aim to analyse molecular changes or “signatures” associated with early stages of pancreatic carcinogenesis by using the combination of: (i) Label-Free Quantitative Proteomics (LFQP)... Read More about Quantitative proteomics of pancreatic cyst fluid for early diagnosis of cancer..

An age-associated reduction in Nav1.5 protein expression correlates with an increase in Nav1.8 protein expression in the right atrial appendage of the human heart. (2020)
Presentation / Conference Contribution
Isaac, E., Cooper, S., Lancaster, M., Loubani, M., & Jones, S. An age-associated reduction in Nav1.5 protein expression correlates with an increase in Nav1.8 protein expression in the right atrial appendage of the human heart. Presented at Basic Cardiovascular Sciences Scientific Sessions 2020, Online

Background: Nav1.5 is the predominantly expressed voltage-gated sodium channel (VGSC) isoform in the heart, responsible for phase 0 of the action potential. Our rodent studies have shown expression of neuronal isoform Nav1.8 protein in the adult hear... Read More about An age-associated reduction in Nav1.5 protein expression correlates with an increase in Nav1.8 protein expression in the right atrial appendage of the human heart..

Conformational studies of tylosin A, tylosin B, erythromycin B and erythromycin C and full assignments of tylosin A in CDCl3 and tylosin B in phosphate buffered D2O (2017)
Presentation / Conference Contribution
Arsic, B., Regan, . A., Morris, G., Oates, A., McBain, . A., & Barber, J. (2017, June). Conformational studies of tylosin A, tylosin B, erythromycin B and erythromycin C and full assignments of tylosin A in CDCl3 and tylosin B in phosphate buffered D2O. Poster presented at 1st RSC Anglo-Nordic Medicinal Chemistry Symposium, Copenhagen, Denmark

Abstract P2-02-03: the collagen receptor Endo180: a metastatic plasma marker in breast cancer modulated by bisphosphonate treatment (2012)
Presentation / Conference Contribution
Sturge, J., Caley, M., Purshouse, K., Fonseca, A.-V., Rodriguez-Teja, M., Kogianni, G., Waxman, J., & Palmieri, C. (2012, December). Abstract P2-02-03: the collagen receptor Endo180: a metastatic plasma marker in breast cancer modulated by bisphosphonate treatment. Presented at Abstracts: Thirty-Fifth Annual CTRC‐AACR San Antonio Breast Cancer Symposium‐‐ Dec 4‐8, 2012; San Antonio, TX

OC6. Endo180 function in metastatic prostate cancer bone lesions (2008)
Presentation / Conference Contribution
Kogianni, G., Eleftheriou, K., Waxman, J., Cobb, J. P., & Sturge, J. OC6. Endo180 function in metastatic prostate cancer bone lesions. Presented at VII International Conference on Cancer Induced Bone Disease, Edinburgh

Hyperbaric oxygen restores the antioxidant defence mechansim following exercise in patients with intermittent claudication (2001)
Presentation / Conference Contribution
Abidia, A., Kuhan, G., Laden, G., Bahia, H., Chetter, I., Greenman, J., & McCollum, P. Hyperbaric oxygen restores the antioxidant defence mechansim following exercise in patients with intermittent claudication

BACKGROUND: Intermittent claudication represents a minor ischaemia reperfusion episode. Exposure to hyperbaric oxygen during such episodes is a concern to many vascular surgeons because of the theoretical risk of generating excess free radicals. We a... Read More about Hyperbaric oxygen restores the antioxidant defence mechansim following exercise in patients with intermittent claudication.

The effects of hypo- and hyperglycemia during lipolysis-like conditions on bovine oocyte maturation, subsequent embryo developmental and glucose metabolism
Presentation / Conference Contribution
Sturmey, R., Andries, S., Bols, P., De Bie, J., Desmet, K., Leroy, J., & Marei, W. The effects of hypo- and hyperglycemia during lipolysis-like conditions on bovine oocyte maturation, subsequent embryo developmental and glucose metabolism

Abstract of a conference paper presented at the 31st meeting of the European Embryo Transfer Associaton, 11-12 September 2015, Ghent, Belgium.

Microfluidic culture of head and neck tumour maintains viability, as shown by single cell analysis, providing potential for novel applications and personalised medicine
Presentation / Conference Contribution
Bower, R., Green, V., Kuvshinov, D., Crank, S., Stafford, N., & Greenman, J. (2016, October). Microfluidic culture of head and neck tumour maintains viability, as shown by single cell analysis, providing potential for novel applications and personalised medicine. Presented at 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016, Dublin, Ireland

The current paper details a succinct characterisation of an in-house designed microfluidic culture device. The maintenance of tissue viability was determined by studying single cells, following dissociation, of head and neck tumour pre and post cultu... Read More about Microfluidic culture of head and neck tumour maintains viability, as shown by single cell analysis, providing potential for novel applications and personalised medicine.

Collagen remodelling by osteoblast and prostate vancer vell interactions in metastatic bone lesions
Presentation / Conference Contribution
Sturge, J. (2009, May). Collagen remodelling by osteoblast and prostate vancer vell interactions in metastatic bone lesions. Presented at BIT‘s 2nd Annual World Cancer Congess 2009, Beijing

A major clinical complication in patients with advanced prostate cancer is metastasis to bone where osteoblastic and/or osteoclastic activity results in a highly destructive tissue remodelling process.Recent in vivo studies have identified important... Read More about Collagen remodelling by osteoblast and prostate vancer vell interactions in metastatic bone lesions.

Anticancer properties of Thymbra capitata and Helichrysum italicum essential oils
Presentation / Conference Contribution
Juliana, P., Marco, L., Célia, C., Lígia, S., & Pires, I. M. D. S. (2014, July). Anticancer properties of Thymbra capitata and Helichrysum italicum essential oils. Presented at IMMR | International Meeting on Marine Research 2014, Peniche, Portugal

An essential oil (EO) is defined internationally as the product obtained by hydrodistillation, of a plant or some parts of it. They are aromatic oily liquids, volatile, characterized by a strong odour, rarely coloured, and generally with a lower dens... Read More about Anticancer properties of Thymbra capitata and Helichrysum italicum essential oils.

Assessment of the properties of the essential oil from Ridolfia segetum Moris (Portugal) on cancer cell viability
Presentation / Conference Contribution
Poças, J., Lemos, M., Cabral, C., Cavaleiro, C., Cruz, M., Salgueiro, L., & Pires, I. (2014, August). Assessment of the properties of the essential oil from Ridolfia segetum Moris (Portugal) on cancer cell viability. Presented at 62nd International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research, Guimarães, Portugal

Ridolfia segetum Moris, commonly known as corn parsley, false fennel, or false caraway, is distributed throughout the Mediterranean region. It belongs to the Apiaceae (carrot or parsley family), which includes well-known aromatic and medicinal plants... Read More about Assessment of the properties of the essential oil from Ridolfia segetum Moris (Portugal) on cancer cell viability.