All Outputs (31)

Endovenous laser ablation in the treatment of small saphenous varicose veins: does site of access influence early outcomes? (2012)
Journal Article
Samuel, N., Wallace, T., Carradice, D., Shahin, Y., Mazari, F. A. K., & Chetter, I. C. (2012). Endovenous laser ablation in the treatment of small saphenous varicose veins: does site of access influence early outcomes?. Vascular and endovascular surgery, 46(4), 310-314. https://doi.org/10.1177/1538574412443316

Objective: The study was performed to evaluate the clinical and technical efficacy of endovenous laser ablation (EVLA) of small saphenous varicosities, particularly in relation to the site of endovenous access. Methods: Totally 59 patients with unila... Read More about Endovenous laser ablation in the treatment of small saphenous varicose veins: does site of access influence early outcomes?.

Pilot and feasibility study: comparative proteomic analysis by 2-DE MALDI TOF/TOF MS reveals 14-3-3 proteins as putative biomarkers of response to neoadjuvant chemotherapy in ER-positive breast cancer (2012)
Journal Article
Hodgkinson, V. C., Agarwal, V., ElFadl, D., Fox, J. N., McManus, P. L., Mahapatra, T. K., …Cawkwell, L. (2012). Pilot and feasibility study: comparative proteomic analysis by 2-DE MALDI TOF/TOF MS reveals 14-3-3 proteins as putative biomarkers of response to neoadjuvant chemotherapy in ER-positive breast cancer. Journal of Proteomics, 75(9), 2745-2752. https://doi.org/10.1016/j.jprot.2012.03.049

Neoadjuvant chemotherapy is used to treat oestrogen receptor-positive breast cancer however chemo-resistance is a major obstacle in this molecular subtype. The ability to predict tumour response would allow chemotherapy administration to be directed... Read More about Pilot and feasibility study: comparative proteomic analysis by 2-DE MALDI TOF/TOF MS reveals 14-3-3 proteins as putative biomarkers of response to neoadjuvant chemotherapy in ER-positive breast cancer.

Factors affecting the patency of arteriovenous fistulas for dialysis access (2012)
Journal Article
Smith, G. E., Gohil, R., & Chetter, I. C. (2012). Factors affecting the patency of arteriovenous fistulas for dialysis access. Journal of vascular surgery, 55(3), 849-855. https://doi.org/10.1016/j.jvs.2011.07.095

Characterization of the effects of cross-linking of macrophage CD44 associated with increased phagocytosis of apoptotic PMN (2012)
Journal Article
Hart, S. P., Rossi, A. G., Haslett, C., & Dransfield, I. (2012). Characterization of the effects of cross-linking of macrophage CD44 associated with increased phagocytosis of apoptotic PMN. PLoS ONE, 7(3), e33142. https://doi.org/10.1371/journal.pone.0033142

Control of macrophage capacity for apoptotic cell clearance by soluble mediators such as cytokines, prostaglandins and lipoxins, serum proteins, and glucocorticoids may critically determine the rate at which inflammation resolves. Previous studies su... Read More about Characterization of the effects of cross-linking of macrophage CD44 associated with increased phagocytosis of apoptotic PMN.

Cognitive behavioural intervention for adults with anxiety complications of asthma: Prospective randomised trial (2012)
Journal Article
Parry, G. D., Cooper, C. L., Moore, J. M., Yadegarfar, G., Campbell, M. J., Esmonde, L., …Hutchcroft, B. J. (2012). Cognitive behavioural intervention for adults with anxiety complications of asthma: Prospective randomised trial. Respiratory medicine, 106(6), 802-810. https://doi.org/10.1016/j.rmed.2012.02.006

Background: High levels of asthma-related fear and panic exacerbate asthma symptoms and complicate the management of asthma. Asthma-specific fear may be reduced by a cognitive behavioural intervention. We aimed to test if there is a reduction in asth... Read More about Cognitive behavioural intervention for adults with anxiety complications of asthma: Prospective randomised trial.

Evolution of an endovenous laser ablation practice for varicose veins (2012)
Journal Article
Samuel, N., Wallace, T., Carradice, D., Smith, G., Mazari, F., & Chetter, I. (2013). Evolution of an endovenous laser ablation practice for varicose veins. Phlebology, 28(5), 248-256. https://doi.org/10.1258/phleb.2011.011103

Objective We aimed to assess the evolution of an endovenous laser ablation (EVLA) practice in the management of varicose veins in a university teaching hospital vascular surgical unit, over five years. Methods This was a retrospective review of a pro... Read More about Evolution of an endovenous laser ablation practice for varicose veins.

Proteomic identification of predictive biomarkers of resistance to neoadjuvant chemotherapy in luminal breast cancer: a possible role for 14-3-3 theta/tau and tBID? (2012)
Journal Article
Hodgkinson, V. C., ELFadl, D., Agarwal, V., Garimella, V., Russell, C., Long, E. D., …Cawkwell, L. (2012). Proteomic identification of predictive biomarkers of resistance to neoadjuvant chemotherapy in luminal breast cancer: a possible role for 14-3-3 theta/tau and tBID?. Journal of Proteomics, 75(4), 1276-1283. https://doi.org/10.1016/j.jprot.2011.11.005

Introduction: Chemotherapy resistance is a major obstacle in effective neoadjuvant treatment for estrogen receptor-positive breast cancer. The ability to predict tumour response would allow chemotherapy administration to be directed towards only thos... Read More about Proteomic identification of predictive biomarkers of resistance to neoadjuvant chemotherapy in luminal breast cancer: a possible role for 14-3-3 theta/tau and tBID?.

Procedure-based assessments: an evaluation of their role in reflective learning (2012)
Journal Article
Green, L., & Chetter, I. (2012). Procedure-based assessments: an evaluation of their role in reflective learning. Bulletin of the Royal College of Surgeons of England, 94(1), 28-30. https://doi.org/10.1308/147363512x13189526437838

Procedure-based assessment (PBA) has, together with other common workplace assessments, become the cornerstone of a surgical trainee's evaluation process, the annual review of competency progression.

Saphenopopliteal ligation and stripping of small saphenous vein: does extended stripping provide better results? (2012)
Journal Article
Samuel, N., Carradice, D., Wallace, T., Smith, G. E., Mazari, F. A. K., & Chetter, I. (2012). Saphenopopliteal ligation and stripping of small saphenous vein: does extended stripping provide better results?. Phlebology, 27(8), 390-397. https://doi.org/10.1258/phleb.2011.011063

Objective Saphenopopliteal ligation (SPL) for venous insufficiency is a challenging procedure, with mixed results being reported. The role of stripping of the small saphenous vein (SSV) is contentious. This prospective observational study aimed to as... Read More about Saphenopopliteal ligation and stripping of small saphenous vein: does extended stripping provide better results?.

Inflammatory stimuli up-regulate transient receptor potential vanilloid-1 expression in human bronchial fibroblasts (2012)
Journal Article
Sadofsky, L. R., Ramachandran, R., Crow, C., Cowen, M., Compton, S. J., & Morice, A. H. (2012). Inflammatory stimuli up-regulate transient receptor potential vanilloid-1 expression in human bronchial fibroblasts. Experimental Lung Research, 38(2), 75-81. https://doi.org/10.3109/01902148.2011.644027

Lung fibroblasts are involved in interstitial lung disease, chronic asthma, and chronic obstructive pulmonary disease (COPD). The expanded fibroblast population in airway disease leads to airway remodeling and contributes to the inflammatory process... Read More about Inflammatory stimuli up-regulate transient receptor potential vanilloid-1 expression in human bronchial fibroblasts.

The effect of parathyroidectomy on neuropsychological symptoms and biochemical parameters in patients with asymptomatic primary hyperparathyroidism: pHPT neuropsychological symptoms (2012)
Journal Article
Kahal, H., Aye, M., Rigby, A. S., Sathyapalan, T., England, R. J. A., & Atkin, S. L. (2012). The effect of parathyroidectomy on neuropsychological symptoms and biochemical parameters in patients with asymptomatic primary hyperparathyroidism: pHPT neuropsychological symptoms. Clinical Endocrinology, 76(2), 196-200. https://doi.org/10.1111/j.1365-2265.2011.04197.x

Background With increased biochemical screening, primary hyperparathyroidism (pHPT) is often discovered incidentally whilst patients are asymptomatic. Objective To assess the impact of parathyroidectomy on neuropsychological symptoms and biochemical... Read More about The effect of parathyroidectomy on neuropsychological symptoms and biochemical parameters in patients with asymptomatic primary hyperparathyroidism: pHPT neuropsychological symptoms.