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The role of high resolution oesophageal manometry in occult respiratory symptoms (2018)
Journal Article
Burke, J. M., Jackson, W., & Morice, A. H. (2018). The role of high resolution oesophageal manometry in occult respiratory symptoms. Respiratory medicine, 138, 47-49. https://doi.org/10.1016/j.rmed.2018.03.027

Purpose: Cough Hypersensitivity Syndrome is the urge to cough following minimal stimulation, but its mechanism and method of provocation remain unexplained. 121 patients (44 males, 77 females; age range 18–81 years) were evaluated. Procedures: High r... Read More about The role of high resolution oesophageal manometry in occult respiratory symptoms.

The effect of pH on citric acid cough challenge: A randomised control trial in chronic cough and healthy volunteers (2018)
Journal Article
Rai, Z. L., Fowles, H. E., Wright, C., Howard, J., & Morice, A. H. (2018). The effect of pH on citric acid cough challenge: A randomised control trial in chronic cough and healthy volunteers. Respiratory Physiology and Neurobiology, 257, 51-54. https://doi.org/10.1016/j.resp.2018.02.013

© 2018 Elsevier B.V. Introduction: Citric acid has been used for over six decades to induce cough; however the mechanism of its pro-tussive effect is still not fully understood. We assessed the response to inhalation of citric acid at varying levels... Read More about The effect of pH on citric acid cough challenge: A randomised control trial in chronic cough and healthy volunteers.

Phenotyping patients with chronic cough: Evaluating the ability to predict the response to anti-inflammatory therapy (2018)
Journal Article
Sadeghi, M. H., Wright, C. E., Hart, S., Crooks, M., & Morice, A. (2018). Phenotyping patients with chronic cough: Evaluating the ability to predict the response to anti-inflammatory therapy. Annals of Allergy, Asthma and Immunology, 120(3), 285-291. https://doi.org/10.1016/j.anai.2017.12.004

© 2017 Background: Whether the fraction of exhaled nitric oxide (FeNO) measurement can predict the response to anti-inflammatory treatment in chronic cough is unknown. Objective: To explore whether the effectiveness of treatment with 10 mg of montelu... Read More about Phenotyping patients with chronic cough: Evaluating the ability to predict the response to anti-inflammatory therapy.

Salivary and serum androgens with anti-Müllerian hormone measurement for the diagnosis of polycystic ovary syndrome (2018)
Journal Article
Sathyapalan, T., Al-Qaissi, A., Kilpatrick, E. S., Dargham, S. R., Keevil, B., & Atkin, S. L. (2018). Salivary and serum androgens with anti-Müllerian hormone measurement for the diagnosis of polycystic ovary syndrome. Scientific reports, 8(1), Article 3795. https://doi.org/10.1038/s41598-018-22176-1

To determine the predictive value of a raised androgen level with an elevated anti-Müllerian hormone (AMH) for the diagnosis or exclusion of polycystic ovary syndrome (PCOS), a prospective cross-sectional study of 170 women (105 with PCOS type A and... Read More about Salivary and serum androgens with anti-Müllerian hormone measurement for the diagnosis of polycystic ovary syndrome.

Cancer patients’ experiences of living with venous thromboembolism: A systematic review and qualitative thematic synthesis (2018)
Journal Article
Benelhaj, N. B., Hutchinson, A., Maraveyas, A. M., Seymour, J. D., Ilyas, M. W., & Johnson, M. J. (2018). Cancer patients’ experiences of living with venous thromboembolism: A systematic review and qualitative thematic synthesis. Palliative medicine, 32(5), 1010-1020. https://doi.org/10.1177/0269216318757133

Background: Cancer-Associated thrombosis is common. Recommended treatment is daily injected low-molecular-weight heparin for 6months. Most studies focus on prophylaxis and treatment; few have explored patients’ experience. Aims To identify and sy... Read More about Cancer patients’ experiences of living with venous thromboembolism: A systematic review and qualitative thematic synthesis.

Effects of growth hormone replacement on peripheral muscle and exercise capacity in severe growth hormone deficiency (2018)
Journal Article
Gonzalez, S., Sathyapalan, T., Javed, Z., & Atkin, S. L. (2018). Effects of growth hormone replacement on peripheral muscle and exercise capacity in severe growth hormone deficiency. Frontiers in endocrinology, 9(FEB), 56. https://doi.org/10.3389/fendo.2018.00056

Aims We evaluate prevalence of new abnormal glucose tolerance (AGT) in post-MI survivors without known diabetes (DM) if guidelines are followed and compare the ability of admission (APG), fasting (FPG) and 2-h post-load plasma glucose (2h-PG) to pred... Read More about Effects of growth hormone replacement on peripheral muscle and exercise capacity in severe growth hormone deficiency.

Two-hour post-challenge glucose is a better predictor of adverse outcome after myocardial infarction than fasting or admission glucose in patients without diabetes (2018)
Journal Article
Chattopadhyay, S., George, A., John, J., & Sathyapalan, T. (2018). Two-hour post-challenge glucose is a better predictor of adverse outcome after myocardial infarction than fasting or admission glucose in patients without diabetes. Acta Diabetologica, 55(5), 449–458. https://doi.org/10.1007/s00592-018-1114-2

Aims We evaluate prevalence of new abnormal glucose tolerance (AGT) in post-MI survivors without known diabetes (DM) if guidelines are followed and compare the ability of admission (APG), fasting (FPG) and 2-h post-load plasma glucose (2h-PG) to pred... Read More about Two-hour post-challenge glucose is a better predictor of adverse outcome after myocardial infarction than fasting or admission glucose in patients without diabetes.

The effect of a simulated commercial flight environment with hypoxia and low humidity on clotting, platelet, and endothelial function in participants with type 2 diabetes - A cross-over study (2018)
Journal Article
Konya, J., Spurgeon, B. E. J., Al Qaissi, A., Sathyapalan, T., Ajjan, R., Madden, L., …Atkin, S. L. (2018). The effect of a simulated commercial flight environment with hypoxia and low humidity on clotting, platelet, and endothelial function in participants with type 2 diabetes - A cross-over study. Frontiers in endocrinology, 9(FEB), Article 26. https://doi.org/10.3389/fendo.2018.00026

© 2018 Konya, Al Qaissi, Sathyapalan, Ajjan, Madden, Naseem, Garrett, Kilpatrick and Atkin. Aims: To determine if clotting, platelet, and endothelial function were affected by simulated short-haul commercial air flight conditions (SF) in participants... Read More about The effect of a simulated commercial flight environment with hypoxia and low humidity on clotting, platelet, and endothelial function in participants with type 2 diabetes - A cross-over study.

Is cough important in acute exacerbations of COPD? (2018)
Journal Article
Crooks, M. G., Brown, T., & Morice, A. H. (2018). Is cough important in acute exacerbations of COPD?. Respiratory Physiology and Neurobiology, 257, 30-35. https://doi.org/10.1016/j.resp.2018.02.005

Chronic obstructive pulmonary disease is predicted to become the 4th leading cause of death worldwide by 2030. The natural history of the disease includes progressive symptoms punctuated by acute exacerbations during which symptoms rapidly deteriorat... Read More about Is cough important in acute exacerbations of COPD?.

Preferred exercise modalities in patients with intermittent claudication (2018)
Journal Article
Harwood, A., Hitchman, L. H., Ingle, L., Doherty, P., & Chetter, I. C. (2018). Preferred exercise modalities in patients with intermittent claudication. Journal of Vascular Nursing, 36(2), 81-84. https://doi.org/10.1016/j.jvn.2017.12.002

Conventional supervised exercise programs (SEPs) for claudicants are traditionally based on time-constrained, group-based structured programs usually at a hospital site. Uptake of an SEP is poor, despite the high-level evidence demonstrating its clin... Read More about Preferred exercise modalities in patients with intermittent claudication.

A Microdose PET Study of the Safety, Immunogenicity, Biodistribution, and Radiation Dosimetry of 18F-FBA20FMDV2 for Imaging the Integrin αvβ6 (2018)
Journal Article
Keat, N., Kenny, J., Chen, K., Onega, M., Garman, N., Slack, R. J., …Lukey, P. T. (2018). A Microdose PET Study of the Safety, Immunogenicity, Biodistribution, and Radiation Dosimetry of 18F-FBA20FMDV2 for Imaging the Integrin αvβ6. Journal of Nuclear Medicine Technology, 46(2), 136-143. https://doi.org/10.2967/jnmt.117.203547

The αvβ6 integrin is involved in the pathogenesis of cancer and fibrosis. A radiolabeled 20-amino-acid αvβ6-binding peptide, derived from the foot and mouth virus (NAVPNLRGDLQVLAQKVART [A20FMDV2]), has been developed to image αvβ6 levels preclinicall... Read More about A Microdose PET Study of the Safety, Immunogenicity, Biodistribution, and Radiation Dosimetry of 18F-FBA20FMDV2 for Imaging the Integrin αvβ6.

Assessment of urinary deoxynivalenol biomarkers in UK children and adolescents (2018)
Journal Article
Papageorgiou, M., Wells, L., Williams, C., White, K., De Santis, B., Liu, Y., …Sathyapalan, T. (2018). Assessment of urinary deoxynivalenol biomarkers in UK children and adolescents. Toxins, 10(2), 50. https://doi.org/10.3390/toxins10020050

© 2018 by the authors. Licensee MDPI, Basel, Switzerland. Deoxynivalenol (DON), the mycotoxin produced mainly by Fusarium graminearum and found in contaminated cereal-based foodstuff, has been consistently detected in body fluids in adults. Available... Read More about Assessment of urinary deoxynivalenol biomarkers in UK children and adolescents.

Translocator protein as an imaging marker of macrophage and stromal activation in rheumatoid arthritis pannus (2018)
Journal Article
Narayan, N., Owen, D. R., Mandhair, H., Smyth, E., Carlucci, F., Saleem, A., …Taylor, P. C. (2018). Translocator protein as an imaging marker of macrophage and stromal activation in rheumatoid arthritis pannus. Journal of nuclear medicine, 59(7), 1125-1132. https://doi.org/10.2967/jnumed.117.202200

PET radioligands targeted to translocator protein (TSPO) offer a highly sensitive and specific means of imaging joint inflammation in rheumatoid arthritis (RA). Through high expression of TSPO on activated macrophages, TSPO PET has been widely report... Read More about Translocator protein as an imaging marker of macrophage and stromal activation in rheumatoid arthritis pannus.