All Outputs (163)

Validation of field-based running tests to determine maximal aerobic speed in professional rugby league (2024)
Journal Article
Bennett, T., Marshall, P., Barrett, S., Malone, J., Simpson, A., Bray, J., Christopherson, C., Nickolay, T., Metcalfe, J., & Towlson, C. (2024). Validation of field-based running tests to determine maximal aerobic speed in professional rugby league. PLoS ONE, 19(7 July), Article e0306062. https://doi.org/10.1371/journal.pone.0306062

Practitioners place importance on high-speed running (HSR) to monitor training practice and match-play demands, whilst attempting to maximise fitness and minimize the risk of injury occurrence. Practitioners apply various methods to quantify HSR, suc... Read More about Validation of field-based running tests to determine maximal aerobic speed in professional rugby league.

A co-produced teaching experience to promote nursing students’ care and compassion towards mental health service users (2024)
Digital Artefact
Davenport, C., & O'Brien, S. (2024). A co-produced teaching experience to promote nursing students’ care and compassion towards mental health service users. [Website]

This blog describes a teaching session we co-produced and delivered to around 300 second year student nurses. We recently followed it up by publishing an article reflecting on the experience (O’Brien and Davenport, 2024) and highlighting the need for... Read More about A co-produced teaching experience to promote nursing students’ care and compassion towards mental health service users.

Inter- and intra-observer reliability and agreement of O<inf>2</inf>Pulse inflection during cardiopulmonary exercise testing: A comparison of subjective and novel objective methodology (2024)
Journal Article
Nickolay, T., McGregor, G., Powell, R., Begg, B., Birkett, S., Nichols, S., Ennis, S., Banerjee, P., Shave, R., Metcalfe, J., Hoye, A., & Ingle, L. (2024). Inter- and intra-observer reliability and agreement of O2Pulse inflection during cardiopulmonary exercise testing: A comparison of subjective and novel objective methodology. PLoS ONE, 19(3 March), Article e0299486. https://doi.org/10.1371/journal.pone.0299486

Cardiopulmonary exercise testing (CPET) is the ‘gold standard’ method for evaluating functional capacity, with oxygen pulse (O2Pulse) inflections serving as a potential indicator of myocardial ischaemia. However, the reliability and agreement of iden... Read More about Inter- and intra-observer reliability and agreement of O<inf>2</inf>Pulse inflection during cardiopulmonary exercise testing: A comparison of subjective and novel objective methodology.

Validation of Field-Based Running Tests to Determine Maximal Aerobic Speed in Professional Rugby League: Anonymised data set (2024)
Data
McLaren-Towlson, C., Marshall, P., Simpson, A., Bray, J., & Nickolay, T. (2024). Validation of Field-Based Running Tests to Determine Maximal Aerobic Speed in Professional Rugby League: Anonymised data set. [Data]

Practitioners place importance on high-speed running (HSR) to monitor training practice and match-play demands, whilst attempting to maximise fitness and minimize the risk of injury occurrence. Practitioners apply various methods to quantify HSR, suc... Read More about Validation of Field-Based Running Tests to Determine Maximal Aerobic Speed in Professional Rugby League: Anonymised data set.

Embedding the service user voice to co-produce UK mental health nurse education—A lived experience narrative (2024)
Journal Article
O'Brien, S., & Davenport, C. (2024). Embedding the service user voice to co-produce UK mental health nurse education—A lived experience narrative. Journal of psychiatric and mental health nursing, https://doi.org/10.1111/jpm.13031

What is known on the subject?: Co-production aims to value service user voices and is increasingly used in healthcare. Less is known about how co-production in nursing education is experienced by service users. What the paper adds to existing knowled... Read More about Embedding the service user voice to co-produce UK mental health nurse education—A lived experience narrative.

HVs’ role in providing alcohol advice to women who are pregnant or planning a pregnancy (2024)
Digital Artefact
Walker, J., Smith, L., Hilton, A., Alfred, L., Scholin, L., & Ahankari, A. (2024). HVs’ role in providing alcohol advice to women who are pregnant or planning a pregnancy

Opening paragraph:
Pregnancy is a transformative period in a woman’s life and an important time to lay strong foundations for infant health and wellbeing that can last a lifetime. The health and wellbeing of the mother, her unborn baby and wider fam... Read More about HVs’ role in providing alcohol advice to women who are pregnant or planning a pregnancy.

The role of cardiopulmonary exercise testing for identifying possible silent myocardial ischaemia in people with coronary heart disease (2024)
Thesis
Nickolay, T. The role of cardiopulmonary exercise testing for identifying possible silent myocardial ischaemia in people with coronary heart disease. (Thesis). University of Hull and University of York. https://hull-repository.worktribe.com/output/4659878

This thesis investigates the utility of cardiopulmonary exercise testing (CPET) in assessing and managing patients with coronary artery disease (CAD), particularly focusing on the significance of oxygen pulse (O2Pulse) inflections as a marker for myo... Read More about The role of cardiopulmonary exercise testing for identifying possible silent myocardial ischaemia in people with coronary heart disease.

Promoting an alcohol-free (dry) pregnancy not just for Dry January (2023)
Digital Artefact
Walker, J., Smith, L., Hilton, A., Alfred, L., Scholin, L., & Ahankari, A. (in press). Promoting an alcohol-free (dry) pregnancy not just for Dry January

Opening paragraph:
Many people make resolutions to take steps towards a healthier lifestyle after the New Year, and ‘Dry January’ is an opportunity to think about cutting down on alcohol consumption.

Making healthy resolutions are also important... Read More about Promoting an alcohol-free (dry) pregnancy not just for Dry January.

Effectiveness of short-term isothermic-heat acclimation (4 days) on physical performance in moderately trained males (2022)
Journal Article
Shaw, J., Walkington, C., Cole, E., Gleadall-Siddall, D. O., Burke, R., Bray, J., Simpson, A. J., Vince, R. V., & Garrett, A. T. (2022). Effectiveness of short-term isothermic-heat acclimation (4 days) on physical performance in moderately trained males. PLoS ONE, 17(11), Article e0270093. https://doi.org/10.1371/journal.pone.0270093

Introduction A typical heat acclimation (HA) protocol takes 5–7 d of 60–90 minutes of heat exposure. Identifying the minimum dose of HA required to elicit a heat adapted phenotype could reduce financial constraints on participants and aid in the tape... Read More about Effectiveness of short-term isothermic-heat acclimation (4 days) on physical performance in moderately trained males.

The Evolution of Scientific Visualisations: A Case Study Approach to Big Data for Varied Audiences (2022)
Book Chapter
Lunn, A. J., Shaw, V., & Winder, I. C. (2022). The Evolution of Scientific Visualisations: A Case Study Approach to Big Data for Varied Audiences. In L. Shapiro, & P. M. Rea (Eds.), Biomedical Visualisation (51-84). Springer. https://doi.org/10.1007/978-3-031-10889-1_3

Visual representations of complex data are a cornerstone of how scientific information is shared. By taking large quantities of data and creating accessible visualisations that show relationships, patterns, outliers, and conclusions, important resear... Read More about The Evolution of Scientific Visualisations: A Case Study Approach to Big Data for Varied Audiences.

Effectiveness of short-term heat acclimation on intermittent sprint performance in the heat with moderately trained males. (2022)
Journal Article
Garrett, A. T., Birkett, M., Gleadall-Siddall, D. O., Burke, R., Bray, J., & Nation, F. (2022). Effectiveness of short-term heat acclimation on intermittent sprint performance in the heat with moderately trained males. Journal of Human Performance in Extreme Environments, 17(1), Article 4. https://doi.org/10.7771/2327-2937.1139

Introduction: Effectiveness of short-term heat acclimation (STHA), over 5-days (permissive dehydration), on intermittent heat stress test (HST) with males.

Methods: Ten, moderately-trained, males (mean [SD]; age 25.6 [8.9] y; stature 180.7 [5.6]... Read More about Effectiveness of short-term heat acclimation on intermittent sprint performance in the heat with moderately trained males..

Making Sense of Evidence: Using Research Training to Promote Organisational Change (2022)
Book Chapter
Wilkinson, K., Boyd, K., Pearson, M., Farrimond, H., Lang, I. A., Fleischer, D., Poole, A., Ralph, N., & Rappert, B. (2022). Making Sense of Evidence: Using Research Training to Promote Organisational Change. In George Mason Police Research Group, & D. Weisburd (Eds.), Translational Criminology in Policing (64-85). Routledge. https://doi.org/10.4324/9781003153009-7

The International Association of Chiefs of Police (IACP) is perhaps the most prominent advocate for such partnerships. Problems confronting public institutions have become more complex in recent years. A number of fields and disciplines have recogniz... Read More about Making Sense of Evidence: Using Research Training to Promote Organisational Change.

Practical considerations of dissolved oxygen levels for platelet function under hypoxia (2021)
Journal Article
Kusanto, B., Gordon, A., Naylor-Adamson, L., Atkinson, L., Coupland, C., Booth, Z., Ahmed, Y., Pires, I. M., Stasiuk, G. J., Sturmey, R., Calaminus, S. D., & Arman, M. (2021). Practical considerations of dissolved oxygen levels for platelet function under hypoxia. International Journal of Molecular Sciences, 22(24), Article 13223. https://doi.org/10.3390/ijms222413223

Investigating human platelet function in low-oxygen environments is important in multiple settings, including hypobaric hypoxia (e.g., high altitude), sea level hypoxia-related disease, and thrombus stability. These studies often involve drawing bloo... Read More about Practical considerations of dissolved oxygen levels for platelet function under hypoxia.

Bruton’s tyrosine kinase inhibitors impair FcγRIIA-driven platelet responses to bacteria in chronic lymphocytic leukemia (2021)
Journal Article
Naylor-Adamson, L., Chacko, A., Booth, Z., Caserta, S., Jarvis, J., Khan, S., Hart, S. P., Rivero, F., Allsup, D. J., & Arman, M. (2021). Bruton’s tyrosine kinase inhibitors impair FcγRIIA-driven platelet responses to bacteria in chronic lymphocytic leukemia. Frontiers in immunology, 12, Article 766272. https://doi.org/10.3389/fimmu.2021.766272

Bacterial infections are a major cause of morbidity and mortality in chronic lymphocytic leukemia (CLL), and infection risk increases in patients treated with the Bruton’s tyrosine kinase (Btk) inhibitor, ibrutinib. Btk and related kinases (like Tec)... Read More about Bruton’s tyrosine kinase inhibitors impair FcγRIIA-driven platelet responses to bacteria in chronic lymphocytic leukemia.

Anatomy in Ancient China: How Acupuncture Meridians Were First Identified (2021)
Journal Article
Shaw, V., & Winder, I. C. (2021). Anatomy in Ancient China: How Acupuncture Meridians Were First Identified. Acupuncture in Physiotherapy : Journal of the Acupuncture Association of Chartered Physiotherapists, 33(2), Article 11-18

Acupuncture meridians are usually considered esoteric structures which serve as conduits for invisible Qi or life force. We argue, however, that the earliest texts describing meridians, the Mawangdui medical manuscripts, are in fact an anatomical atl... Read More about Anatomy in Ancient China: How Acupuncture Meridians Were First Identified.

Inhibition of arginine methylation impairs platelet function (2021)
Journal Article
Marsden, A. J., Riley, D. R. J., Barry, A., Khalil, J. S., Guinn, B. A., Kemp, N. T., Rivero, F., & Beltran-Alvarez, P. (in press). Inhibition of arginine methylation impairs platelet function. ACS Pharmacology & Translational Science, https://doi.org/10.1021/acsptsci.1c00135

Protein arginine methyltransferases (PRMTs) catalyze the transfer of methyl groups to arginine residues in proteins. PRMT inhibitors are novel, promising drugs against cancer that are currently in clinical trials, which include oral administration of... Read More about Inhibition of arginine methylation impairs platelet function.

Spheroid-on-chip microfluidic technology for the evaluation of the impact of continuous flow on metastatic potential in cancer models in vitro (2021)
Journal Article
Collins, T., Pyne, E., Christensen, M., Iles, A., Pamme, N., & Pires, I. M. (2021). Spheroid-on-chip microfluidic technology for the evaluation of the impact of continuous flow on metastatic potential in cancer models in vitro. Biomicrofluidics, 15(4), Article 044103. https://doi.org/10.1063/5.0061373

The majority of cancer deaths are linked to tumor spread, or metastasis, but 3D in vitro metastasis models relevant to the tumor microenvironment (including interstitial fluid flow) remain an area of unmet need. Microfluidics allows us to introduce c... Read More about Spheroid-on-chip microfluidic technology for the evaluation of the impact of continuous flow on metastatic potential in cancer models in vitro.

The vertebral artery blood supply to the brain and its relationship with cognition across the taxonomic classes: Mammalia and Aves (2021)
Presentation / Conference Contribution
Lunn, A., Winder, I. C., & Shaw, V. (2021, July). The vertebral artery blood supply to the brain and its relationship with cognition across the taxonomic classes: Mammalia and Aves. Poster presented at Anatomical Society Summer Meeting 2021: Cutting Edge Anatomy, Glasgow

Human brains require the most energy per unit of mass of any animal and also have the largest cortical neuron count, which is afforded by having the largest primate brain and abiding by economic scaling rules. Cortical neuron count is one of the most... Read More about The vertebral artery blood supply to the brain and its relationship with cognition across the taxonomic classes: Mammalia and Aves.

Love is in the hair: arginine methylation of human hair proteins as novel cardiovascular biomarkers (2021)
Journal Article
Marsden, A. J., Riley, D. R., Birkett, S., Rodriguez-Barucg, Q., Guinn, B. A., Carroll, S., Ingle, L., Sathyapalan, T., & Beltran-Alvarez, P. (in press). Love is in the hair: arginine methylation of human hair proteins as novel cardiovascular biomarkers. Amino acids, https://doi.org/10.1007/s00726-021-03024-5

Cardiovascular disease is the major cause of death worldwide. Extensive cardiovascular biomarkers are available using blood tests but very few, if any, investigations have described non-invasive tests for cardiovascular biomarkers based on readily av... Read More about Love is in the hair: arginine methylation of human hair proteins as novel cardiovascular biomarkers.

aDolescents gEnder surVey, rEsponsible coupLes evaluatiOn, and capacity building Project in India (DEVELOP): a study protocol [version 2; peer review: 2 approved] (2021)
Journal Article
Ahankari, A., Hayter, M., Whitfield, C., Ali, P., Giridhari, S., Tambe, S., Kabra, P., Rayamane, K., & Ovseiko, P. (2021). aDolescents gEnder surVey, rEsponsible coupLes evaluatiOn, and capacity building Project in India (DEVELOP): a study protocol [version 2; peer review: 2 approved]. F1000Research, 8, Article 958. https://doi.org/10.12688/f1000research.19521.2

Domestic violence and assault (DVA) against women is a serious concern in India. This affects the health and wellbeing of victims and their dependents. Published evidence has documented a variety of reasons for such violence in Indian societies, pavi... Read More about aDolescents gEnder surVey, rEsponsible coupLes evaluatiOn, and capacity building Project in India (DEVELOP): a study protocol [version 2; peer review: 2 approved].