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All Outputs (700)

Interventions to improve the quality of life in patients living with endocrine conditions A (2025)
Thesis
Ssemmondo, E. (2025). Interventions to improve the quality of life in patients living with endocrine conditions A. (Thesis). Hull York Medical School. https://hull-repository.worktribe.com/output/5006299

Introduction
Patients living with chronic endocrine conditions experience a burden of disease which affects their quality of life compared to healthy controls. In people living with type 1 and type 2 diabetes, this may be due to micro or macrovascul... Read More about Interventions to improve the quality of life in patients living with endocrine conditions A.

Combined Head-Mounted Display Virtual Reality and Electroencephalography in the Study of Working Memory (2024)
Thesis
Durnin, A. (2024). Combined Head-Mounted Display Virtual Reality and Electroencephalography in the Study of Working Memory. (Thesis). Hull York Medical School. https://hull-repository.worktribe.com/output/5005212

Modern head-mounted display virtual reality (HMD-VR) is used to present immersive virtual environments which reduce external distractions during research. Working memory load (WML) is commonly measured using electroencephalography (EEG), which non-in... Read More about Combined Head-Mounted Display Virtual Reality and Electroencephalography in the Study of Working Memory.

Barriers and facilitators for cardiopulmonary resuscitation discussions with people with heart failure (2024)
Journal Article
Barnes-Harris, M. M., Datla, S., Abel, A., Clark, A. L., & Johnson, M. J. (2024). Barriers and facilitators for cardiopulmonary resuscitation discussions with people with heart failure. PLoS ONE, 19(12), Article e0314631. https://doi.org/10.1371/journal.pone.0314631

Background Care planning with people with advanced heart failure enables appropriate care, and prevents futile interventions, such as cardio-pulmonary resuscitation (CPR). Aim To explore what motivates clinicians to conduct, and people with heart fai... Read More about Barriers and facilitators for cardiopulmonary resuscitation discussions with people with heart failure.

Human Brain Responses to Fast-Moving Consumer Goods Using Electroencephalography (2024)
Thesis
Aksoy, M. (2024). Human Brain Responses to Fast-Moving Consumer Goods Using Electroencephalography. (Thesis). University of Hull. https://hull-repository.worktribe.com/output/4910116

The utilisation of brain monitoring methods in the field of neuroscience provides an opportunity to go beyond subjective data collection methods such as questionnaires, focus groups, and interviews. Using these monitoring methods allows researchers i... Read More about Human Brain Responses to Fast-Moving Consumer Goods Using Electroencephalography.

Meaningful patient and public engagement in dissemination—embedding co-production in dementia research (2024)
Journal Article
de Wolf-Linder, S., Kramer, I., Hersperger, M., Schubert, M., Bachi, S., Stolz, M., Wolverson, E., & Ramsenthaler, C. (2024). Meaningful patient and public engagement in dissemination—embedding co-production in dementia research. Frontiers in Dementia, 3, Article 1426019. https://doi.org/10.3389/frdem.2024.1426019

Background: Patient and Public Involvement and Engagement (PPIE) is still underutilised in both dementia research and corresponding dissemination activities.

Aim: To describe the methods, format, and lessons learned in co-creating and co-producing... Read More about Meaningful patient and public engagement in dissemination—embedding co-production in dementia research.

Addressing hidden tensions and grey areas of general practice: A qualitative study of the experiences of newly qualified GPs attending a course on generalist medicine (2024)
Journal Article
Reeve, J., & Dell Olio, M. (in press). Addressing hidden tensions and grey areas of general practice: A qualitative study of the experiences of newly qualified GPs attending a course on generalist medicine. BJGP Open, 74(746), e637-e643. https://doi.org/10.3399/BJGP.2023.0514

Background
Generalist approaches can help address several challenges facing today’s primary care. However, GPs report insufficient support to deliver advanced generalist medicine (AGM) in daily practice, struggling within a healthcare system that im... Read More about Addressing hidden tensions and grey areas of general practice: A qualitative study of the experiences of newly qualified GPs attending a course on generalist medicine.

Addressing hidden tensions and grey areas of general practice: a qualitative study of the experiences of newly qualified GPs attending a course on generalist medicine (2024)
Journal Article
Dell'Olio, M., & Reeve, J. (2024). Addressing hidden tensions and grey areas of general practice: a qualitative study of the experiences of newly qualified GPs attending a course on generalist medicine. The British journal of general practice : the journal of the Royal College of General Practitioners, 74(746), e637-e643. https://doi.org/10.3399/BJGP.2023.0514

Background Generalist approaches can help address several challenges facing today’s primary care. However, GPs report insufficient support to deliver advanced generalist medicine (AGM) in daily practice, struggling within a healthcare system that imp... Read More about Addressing hidden tensions and grey areas of general practice: a qualitative study of the experiences of newly qualified GPs attending a course on generalist medicine.

Supporting the primary care workforce through training in advanced generalist practice: An evaluation of the Catalyst programme (2024)
Journal Article
Dell'Olio, M., & Reeve, J. (online). Supporting the primary care workforce through training in advanced generalist practice: An evaluation of the Catalyst programme. The Journal of Continuing Education in the Health Professions, https://doi.org/10.1097/CEH.0000000000000566

Introduction:
As a workforce crisis is causing recruitment and retention issues for new to practice GPs, we designed Catalyst, a one-year pilot career development program aiming to help new to practice GPs develop the skills of advanced generalist... Read More about Supporting the primary care workforce through training in advanced generalist practice: An evaluation of the Catalyst programme.

Disease progression in chronic heart failure is linear: Insights from multistate modelling (2024)
Journal Article
Kazmi, S., Kambhampati, C., Rigby, A. S., Cleland, J. G. F., Kazmi, K. S., Cuthbert, J., Pellicori, P., & Clark, A. L. (online). Disease progression in chronic heart failure is linear: Insights from multistate modelling. European journal of heart failure, https://doi.org/10.1002/ejhf.3400

Aims: Understanding the pattern of disease progression in chronic heart failure (HF) may inform patient care and healthcare system design. We used a four-state Markov model to describe the disease trajectory of patients with HF. Methods and results:... Read More about Disease progression in chronic heart failure is linear: Insights from multistate modelling.

The association between completion of supervised exercise therapy and long-term outcomes in patients with intermittent claudication, concomitant sarcopenia and cardiometabolic multimorbidity (2024)
Journal Article
Ravindhran, B., Igwe, C., Nazir, S., Prosser, J., Harwood, A., Lathan, R., Harwood, A. E., Carradice, D., Smith, G. E., Chetter, I. C., & Pymer, S. (online). The association between completion of supervised exercise therapy and long-term outcomes in patients with intermittent claudication, concomitant sarcopenia and cardiometabolic multimorbidity. Annals of vascular surgery, https://doi.org/10.1016/j.avsg.2024.04.032

Introduction: The combination of intermittent claudication (IC), cardiometabolic multimorbidity (CMM), and sarcopenia is associated with worse outcomes than IC alone. This study aimed to identify whether the completion of supervised exercise therapy... Read More about The association between completion of supervised exercise therapy and long-term outcomes in patients with intermittent claudication, concomitant sarcopenia and cardiometabolic multimorbidity.

A Scoping Review of Stigma Related to Prostate Cancer in Black Men (2024)
Journal Article
Bamidele, O., Greenley, S., Ukoha-Kalu, B. O., Titus, O. F., & Nanton, V. (2024). A Scoping Review of Stigma Related to Prostate Cancer in Black Men. Journal of Racial and Ethnic Health Disparities, https://doi.org/10.1007/s40615-024-02070-5

Background: Prostate cancer (CaP) disproportionately affects 1-in-4 Black men and is a stigmatised disease within their communities. Yet, Black men are underrepresented in CaP research concerning stigma, which necessitates a scoping review to map ava... Read More about A Scoping Review of Stigma Related to Prostate Cancer in Black Men.

Internet and Telephone Support for Discontinuing Long-Term Antidepressants: The REDUCE Cluster Randomized Trial (2024)
Journal Article
Kendrick, T., Stuart, B., Bowers, H., Haji Sadeghi, M., Page, H., Dowrick, C., Moore, M., Gabbay, M., Leydon, G. M., Yao, G. L., Little, P., Griffiths, G., Lewis, G., May, C., Moncrieff, J., Johnson, C. F., Macleod, U., Gilbody, S., Dewar-Haggart, R., Williams, S., …Geraghty, A. W. (2024). Internet and Telephone Support for Discontinuing Long-Term Antidepressants: The REDUCE Cluster Randomized Trial. Jama Network Open, 7(6), Article e2418383. https://doi.org/10.1001/jamanetworkopen.2024.18383

Importance: There is significant concern regarding increasing long-term antidepressant treatment for depression beyond an evidence-based duration. Objective: To determine whether adding internet and telephone support to a family practitioner review t... Read More about Internet and Telephone Support for Discontinuing Long-Term Antidepressants: The REDUCE Cluster Randomized Trial.

The prognostic value of simple frailty and malnutrition screening tools for determining surgical risk in patients with chronic limb threatening ischaemia undergoing major vascular surgery: A retrospective cross-sectional study (2024)
Journal Article
Palmer, J., Pymer, S., Smith, G., Ingle, L., Harwood, A., & Chetter, I. (online). The prognostic value of simple frailty and malnutrition screening tools for determining surgical risk in patients with chronic limb threatening ischaemia undergoing major vascular surgery: A retrospective cross-sectional study. Journal of Vascular Societies Great Britain and Ireland, https://doi.org/10.54522/jvsgbi.2024.124

Background: This study aims to explore the prognostic value of simple frailty and malnutrition tools for determining postoperative outcomes at 30 days and 1 year in patients with CLTI undergoing major surgery.
Methods: This was a single-centre retr... Read More about The prognostic value of simple frailty and malnutrition screening tools for determining surgical risk in patients with chronic limb threatening ischaemia undergoing major vascular surgery: A retrospective cross-sectional study.

The Effect of Thiazolidinediones in Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis of Randomised Controlled Trials (2024)
Journal Article
Abdalla, M. A., Shah, N., Deshmukh, H., Sahebkar, A., Östlundh, L., Al-Rifai, R. H., Atkin, S. L., & Sathyapalan, T. (2024). The Effect of Thiazolidinediones in Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis of Randomised Controlled Trials. Advances in Therapy, 41, 2168-2195. https://doi.org/10.1007/s12325-024-02848-3

Introduction: Polycystic ovary syndrome (PCOS) is a complex endocrine condition affecting women of reproductive age. It is characterised by insulin resistance and is a risk for type 2 diabetes mellitus (T2DM). The aim of this study was to review the... Read More about The Effect of Thiazolidinediones in Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.

Evaluation of iron supplementation and its effect on postoperative outcomes in non-anaemic iron deficient patients undergoing surgery, with a focus on lower limb arthroplasty (2024)
Thesis
Randall, J. Evaluation of iron supplementation and its effect on postoperative outcomes in non-anaemic iron deficient patients undergoing surgery, with a focus on lower limb arthroplasty. (Thesis). University of Hull and University of York. https://hull-repository.worktribe.com/output/4659916

Aim
Non-anaemic iron deficiency although identified as a potential area for improving patient outcome in the literature, its effect on patient outcomes post-surgery is an under researched topic, with numerous gaps in the published literature. The ai... Read More about Evaluation of iron supplementation and its effect on postoperative outcomes in non-anaemic iron deficient patients undergoing surgery, with a focus on lower limb arthroplasty.

Outcomes in patients treated with loop diuretics without a diagnosis of heart failure: a retrospective cohort study (2024)
Journal Article
Cuthbert, J. J., Soyiri, I., Lomax, S. J., Turgoose, J., Fuat, A., Cohen, J., & Clark, A. L. (2024). Outcomes in patients treated with loop diuretics without a diagnosis of heart failure: a retrospective cohort study. Heart, 110(12), 854-862. https://doi.org/10.1136/heartjnl-2023-323577

Background Loop diuretics are commonly prescribed in the community, not always to patients with a recorded diagnosis of heart failure (HF). The rate of HF events in patients prescribed loop diuretics without a diagnosis of HF is unknown. Methods This... Read More about Outcomes in patients treated with loop diuretics without a diagnosis of heart failure: a retrospective cohort study.

The differential effect of intravenous iron in patients with non-dialysis chronic kidney disease in terms of fibroblast growth factor 23, phosphate, bone metabolism, functional status and quality of life and cardiovascular variables (2024)
Thesis
Kassianides, X. The differential effect of intravenous iron in patients with non-dialysis chronic kidney disease in terms of fibroblast growth factor 23, phosphate, bone metabolism, functional status and quality of life and cardiovascular variables. (Thesis). University of Hull and University of York. https://hull-repository.worktribe.com/output/4659777

Background: Modern intravenous iron preparations (e.g. ferric derisomaltose (FDI), ferric carboxymaltose (FCM)) are commonly used in non-dialysis-dependent chronic kidney disease (CKD) patients. Despite similar efficacy and safety in terms of previou... Read More about The differential effect of intravenous iron in patients with non-dialysis chronic kidney disease in terms of fibroblast growth factor 23, phosphate, bone metabolism, functional status and quality of life and cardiovascular variables.

The regulatory role of Malat1 on the alternative splicing factor SRSF1 during CD4+ T cell differentiation (2024)
Thesis
Greaves, J. The regulatory role of Malat1 on the alternative splicing factor SRSF1 during CD4+ T cell differentiation. (Thesis). Hull York Medical School. https://hull-repository.worktribe.com/output/4609527

The proper activation and subsequent differentiation of naive CD4+ T cells into effector T helper and regulatory T cells is vital for directing an appropriate adaptive immune response to specific infections. Recent evidence has identified long non-co... Read More about The regulatory role of Malat1 on the alternative splicing factor SRSF1 during CD4+ T cell differentiation.