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Acupuncture needling sensation: the neural correlates of deqi using fMRI (2009)
Journal Article
Asghar, A. U. R., Green, G., Lythgoe, M. F., Lewith, G., & MacPherson, H. (2010). Acupuncture needling sensation: the neural correlates of deqi using fMRI. Brain research, 1315, 111-118. https://doi.org/10.1016/j.brainres.2009.12.019

The needling sensation of deqi is considered by most acupuncturists to be an important component of acupuncture, yet neuroimaging research that investigates this needle sensation has been limited. In this study we have investigated the effect of deqi... Read More about Acupuncture needling sensation: the neural correlates of deqi using fMRI.

Randomized clinical trial of co-amoxiclav versus no antibiotic prophylaxis in varicose vein surgery (2009)
Journal Article
Mekako, A. I., Chetter, I. C., Coughlin, P. A., Hatfield, J., & McCollum, P. T. (2010). Randomized clinical trial of co-amoxiclav versus no antibiotic prophylaxis in varicose vein surgery. British journal of surgery, 97(1), 29-36. https://doi.org/10.1002/bjs.6849

Background: Wound infection rates of up to 16 per cent are reported following varicose vein surgery and the value of antibiotic prophylaxis in clean surgery remains unclear. Methods: Some 443 patients undergoing varicose vein surgery randomly receive... Read More about Randomized clinical trial of co-amoxiclav versus no antibiotic prophylaxis in varicose vein surgery.

TRPA1 agonists evoke coughing in guinea pig and human volunteers (2009)
Journal Article
Birrell, M. A., Belvisi, M. G., Grace, M., Sadofsky, L., Faruqi, S., Hele, D. J., Maher, S. A., Freund-Michel, V., & Morice, A. H. (2009). TRPA1 agonists evoke coughing in guinea pig and human volunteers. American Journal of Respiratory and Critical Care Medicine, 180(11), 1042-1047. https://doi.org/10.1164/rccm.200905-0665OC

Rationale: Cough is the most frequent reason for consultation with a family doctor, or with a general or respiratory physician. Treatment options are limited and one meta-analysis concluded that over-the-counter remedies are ineffective. There is als... Read More about TRPA1 agonists evoke coughing in guinea pig and human volunteers.

Lack of diastolic reserve in patients with heart failure and normal ejection fraction (2009)
Journal Article
Chattopadhyay, S., Alamgir, M. F., Nikitin, N. P., Rigby, A. S., Clark, A. L., & Cleland, J. G. F. (2010). Lack of diastolic reserve in patients with heart failure and normal ejection fraction. Circulation. Heart failure, 3(1), 35-43. https://doi.org/10.1161/CIRCHEARTFAILURE.108.824888

Background-The genesis of symptoms in patients with heart failure (HF) and normal ejection fraction (HFNEF) is unclear. Most investigations of HFNEF have focused on cardiac function at rest although most of these patients are breathless only on exerc... Read More about Lack of diastolic reserve in patients with heart failure and normal ejection fraction.

Intramucosal carcinoma on biopsy reliably predicts invasive colorectal cancer (2009)
Journal Article
MacDonald, A. W., Tayyab, M., Arsalani-Zadeh, R., Hartley, J. E., & Monson, J. R. T. (2009). Intramucosal carcinoma on biopsy reliably predicts invasive colorectal cancer. Annals of Surgical Oncology, 16(12), 3267-3270. https://doi.org/10.1245/s10434-009-0727-7

Background: The diagnosis of invasive malignancy on biopsies from colorectal neoplasms can be challenging. The concept of intramucosal carcinoma as an indicator of invasive malignancy is somewhat controversial within histopathology circles despite cu... Read More about Intramucosal carcinoma on biopsy reliably predicts invasive colorectal cancer.

Quality assurance in flexible sigmoidoscopy: Medical and nonmedical endoscopists (2009)
Journal Article
Maslekar, S., Waudby, P., Avery, G., Monson, J. R. T., & Duthie, G. S. (2010). Quality assurance in flexible sigmoidoscopy: Medical and nonmedical endoscopists. Surgical Endoscopy, 24(1), 89-93. https://doi.org/10.1007/s00464-009-0553-9

Purpose: The clinical assessment of position in colon and hence completion during flexible sigmoidoscopy (FS) is believed to be inaccurate. The technique of applying endomucosal clips with follow-up X-ray has previously been used for establishing com... Read More about Quality assurance in flexible sigmoidoscopy: Medical and nonmedical endoscopists.

Acquired microcephaly: causes, patterns, motor and IQ effects, and associated growth changes (2009)
Journal Article
Baxter, P. S., Rigby, A. S., Rotsaert, M. H. E. P. D., & Wright, I. (2009). Acquired microcephaly: causes, patterns, motor and IQ effects, and associated growth changes. Pediatrics, 124(2), 590-595. https://doi.org/10.1542/peds.2008-2784

OBJECTIVES: The goals were to identify and to classify causes and growth patterns of acquired (or progressive) microcephaly and to look for hypothesized correlations between causes, growth patterns, and developmental quotient/IQ. METHODS: Fifty-one c... Read More about Acquired microcephaly: causes, patterns, motor and IQ effects, and associated growth changes.

Patient satisfaction with lower gastrointestinal endoscopy: doctors, nurse and nonmedical endoscopists (2009)
Journal Article
Maslekar, S., Hughes, M., Gardiner, A., Monson, J. R. T., & Duthie, G. S. (2010). Patient satisfaction with lower gastrointestinal endoscopy: doctors, nurse and nonmedical endoscopists. Colorectal disease, 12(10), 1033-1038. https://doi.org/10.1111/j.1463-1318.2009.01989.x

Aim Assessment of patient satisfaction with lower gastrointestinal endoscopy (LGE) comprising colonoscopy and flexible sigmoidoscopy is gaining increasing importance. We have now trained non healthcare professionals such as nonmedical endoscopists (N... Read More about Patient satisfaction with lower gastrointestinal endoscopy: doctors, nurse and nonmedical endoscopists.

Effect of glucose variability on the long-term risk of microvascular complications in type 1 diabetes (2009)
Journal Article
Kilpatrick, E. S., Rigby, A. S., & Atkin, S. L. (2009). Effect of glucose variability on the long-term risk of microvascular complications in type 1 diabetes. Diabetes Care, 32(10), 1901-1903. https://doi.org/10.2337/dc09-0109

OBJECTIVE This study analyzed data from the Epidemiology of Diabetes Interventions and Complications (EDIC) study to see whether longer-term follow-up of Diabetes Control and Complications Trial (DCCT) patients reveals a role for glycemic instability... Read More about Effect of glucose variability on the long-term risk of microvascular complications in type 1 diabetes.

Network-based activity induced by 4-aminopyridine in rat dorsal horn in vitro is mediated by both chemical and electrical synapses (2009)
Journal Article
Chapman, R. J., Cilia La Corte, P. F., Asghar, A. U. R., & King, A. E. (2009). Network-based activity induced by 4-aminopyridine in rat dorsal horn in vitro is mediated by both chemical and electrical synapses. The Journal of physiology, 587(11), 2499-2510. https://doi.org/10.1113/jphysiol.2009.171777

This study investigated the role of electrical and chemical synapses in sustaining 4-aminopyridine (4-AP)-evoked network activity recorded extracellularly from substantia gelatinosa (SG) of young rat spinal cord in vitro. Superfusion of 4-AP (50 micr... Read More about Network-based activity induced by 4-aminopyridine in rat dorsal horn in vitro is mediated by both chemical and electrical synapses.

Learning from evaluation: A descriptive, student-informed approach (2009)
Journal Article
Hammond, A., Collins, S., Booth, J., & Kalia, S. (2009). Learning from evaluation: A descriptive, student-informed approach. Clinical Teacher, 6(2), 73-78. https://doi.org/10.1111/j.1743-498X.2009.00275.x

Preamble
Meaningful engagement of students in the thoughtful evaluation of teaching is difficult
Students were involved in framing questions and in commenting on the evaluation process
The data supply insights into students' views on being taught... Read More about Learning from evaluation: A descriptive, student-informed approach.

Quality assurance in colonoscopy: role of endomucosal clips (2009)
Journal Article
Maslekar, S., Avery, G., & Duthie, G. S. (2010). Quality assurance in colonoscopy: role of endomucosal clips. Colorectal Disease, 12(7), 651-656. https://doi.org/10.1111/j.1463-1318.2009.01874.x

Objective Quality assurance in colonoscopy is important, and subjective assessment of completion based on endoscopic signs can be inaccurate leading to missed lesions. We aimed to determine the technique of endomucosal clips with follow-up X-rays in... Read More about Quality assurance in colonoscopy: role of endomucosal clips.

Randomized clinical trial of concomitant or sequential phlebectomy after endovenous laser therapy for varicose veins (2009)
Journal Article
Carradice, D., Mekako, A. I., Hatfield, J., & Chetter, I. C. (2009). Randomized clinical trial of concomitant or sequential phlebectomy after endovenous laser therapy for varicose veins. British journal of surgery, 96(4), 369-375. https://doi.org/10.1002/bjs.6556

Background: The management of residual varicosities following endovenous laser therapy (EVLT) for varicose veins is contentious. Ambulatory phlebectomy may be performed concomitantly with the initial EVLT, or sequentially as a secondary procedure. Th... Read More about Randomized clinical trial of concomitant or sequential phlebectomy after endovenous laser therapy for varicose veins.

Randomized clinical trial of Entonox ® versus midazolam-fentanyl sedation for colonoscopy (2009)
Journal Article
Maslekar, S., Gardiner, A., Hughes, M., Culbert, B., & Duthie, G. S. (2009). Randomized clinical trial of Entonox ® versus midazolam-fentanyl sedation for colonoscopy. British journal of surgery, 96(4), 361-368. https://doi.org/10.1002/bjs.6467

Background: Intravenous sedation for colonoscopy is associated with cardiorespiratory complications and delayed recovery. The aim of this randomized clinical trial was to compare the efficacy of Entonox ® (50 per cent nitrous oxide and 50 per cent o... Read More about Randomized clinical trial of Entonox ® versus midazolam-fentanyl sedation for colonoscopy.

Considered evaluation of clinical placements in a new medical school (2009)
Journal Article
Booth, J., Collins, S., & Hammond, A. (2009). Considered evaluation of clinical placements in a new medical school. Assessment and Evaluation in Higher Education, 34(1), 17-29. https://doi.org/10.1080/02602930701773018

This article suggests that quality assessment in the UK has been largely set apart from learning and teaching and reports on a pilot project at the Hull York Medical School which attempted to integrate students' evaluation of their clinical placement... Read More about Considered evaluation of clinical placements in a new medical school.

In Situ Characterization of Elusive Salt Hydrates-The Crystal Structures of the Heptahydrate and Octahydrate of Sodium Sulfate (2008)
Journal Article
Oswald, I. D. H., Hamilton, A., Hall, C., Marshall, W. G., Prior, T. J., & Pulham, C. R. (2008). In Situ Characterization of Elusive Salt Hydrates-The Crystal Structures of the Heptahydrate and Octahydrate of Sodium Sulfate. Journal of the American Chemical Society, 130(52), 17795-17800. https://doi.org/10.1021/ja805429m

An important intermediate phase in the crystallization of aqueous solutions of sodium sulfate is the highly metastable sodium sulfate heptahydrate (Na2SO4 center dot 7H(2)O). This has been structurally characterized for the first time by in situ sing... Read More about In Situ Characterization of Elusive Salt Hydrates-The Crystal Structures of the Heptahydrate and Octahydrate of Sodium Sulfate.

Predictors of short term mortality in heart failure - insights from the Euro Heart Failure survey (2008)
Journal Article
Velavan, P., Khan, N. K., Goode, K., Rigby, A. S., Loh, P. H., Komajda, M., Follath, F., Swedberg, K., Madeira, H., & Cleland, J. G. (2010). Predictors of short term mortality in heart failure - insights from the Euro Heart Failure survey. International journal of cardiology, 138(1), 63-69. https://doi.org/10.1016/j.ijcard.2008.08.004

Objective: To identify factors associated with short term mortality in hospitalised patients with heart failure. Background: Hospitalisation is frequent in patients with heart failure and is associated with a high mortality. Methods: The Euro Heart F... Read More about Predictors of short term mortality in heart failure - insights from the Euro Heart Failure survey.

Low dose cabergoline for hyperprolactinaemia is not associated with clinically significant valvular heart disease (2008)
Journal Article
Wakil, A., Rigby, A. S., Clark, A. L., Kallvikbacka-Bennett, A., & Atkin, S. L. (2008). Low dose cabergoline for hyperprolactinaemia is not associated with clinically significant valvular heart disease. European journal of endocrinology, 159(4), R11-R14. https://doi.org/10.1530/eje-08-0365

OBJECTIVE: Recent trials suggest that using ergot-derived dopamine agonists such as cabergoline in the treatment of Parkinson's disease is associated with an increased risk of valvular heart disease. However, the dose of cabergoline used to treat hyp... Read More about Low dose cabergoline for hyperprolactinaemia is not associated with clinically significant valvular heart disease.

A1C variability and the risk of microvascular complications in type 1 diabetes: Data from the diabetes control and complications trial (2008)
Journal Article
Kilpatrick, E. S., Rigby, A. S., & Atkin, S. L. (2008). A1C variability and the risk of microvascular complications in type 1 diabetes: Data from the diabetes control and complications trial. Diabetes Care, 31(11), 2198-2202. https://doi.org/10.2337/dc08-0864

OBJECTIVE—Debate remains as to whether short- or long-term glycemic instability confers a risk of microvascular complications in addition to that predicted by mean glycemia alone. In this study, we analyzed data from the Diabetes Control and Complica... Read More about A1C variability and the risk of microvascular complications in type 1 diabetes: Data from the diabetes control and complications trial.