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A muscle growth-promoting treatment based on the attenuation of activin/myostatin signalling results in long-term testicular abnormalities (2021)
Journal Article
Vaughan, D., Mitchell, R., Kretz, O., Chambers, D., Lalowski, M., Amthor, H., …Patel, K. (2021). A muscle growth-promoting treatment based on the attenuation of activin/myostatin signalling results in long-term testicular abnormalities. Disease Models and Mechanisms, 14(2), Article dmm047555. https://doi.org/10.1242/dmm.047555

© 2021. Published by The Company of Biologists Ltd. Activin/myostatin signalling acts to induce skeletal muscle atrophy in adult mammals by inhibiting protein synthesis as well as promoting protein and organelle turnover. Numerous strategies have bee... Read More about A muscle growth-promoting treatment based on the attenuation of activin/myostatin signalling results in long-term testicular abnormalities.

Protective effects of dapagliflozin against oxidative stress-induced cell injury in human proximal tubular cells (2021)
Journal Article
Zaibi, N., Li, P., & Xu, S.-Z. (in press). Protective effects of dapagliflozin against oxidative stress-induced cell injury in human proximal tubular cells. PLoS ONE, 16(2), Article e0247234. https://doi.org/10.1371/journal.pone.0247234

Elevated reactive oxygen species (ROS) in type 2 diabetes cause cellular damage in many organs. Recently, the new class of glucose-lowering agents, SGLT-2 inhibitors, have been shown to reduce the risk of developing diabetic complications; however, t... Read More about Protective effects of dapagliflozin against oxidative stress-induced cell injury in human proximal tubular cells.

The association between diabetes-related distress and fear of hypoglycaemia in patients with type 2 diabetes mellitus: A cross-sectional descriptive study (2021)
Journal Article
Li, S., Fang, L., Lee, A., Hayter, M., Zhang, L., Bi, Y., …Zhang, Y. (2021). The association between diabetes-related distress and fear of hypoglycaemia in patients with type 2 diabetes mellitus: A cross-sectional descriptive study. Nursing Open, https://doi.org/10.1002/nop2.800

Aim: The study aimed to explore the association between diabetes-related distress as a dependent variable and fear of hypoglycaemia as a independent variable in Chinese individuals with type 2 diabetes, which can provide a basis for the development o... Read More about The association between diabetes-related distress and fear of hypoglycaemia in patients with type 2 diabetes mellitus: A cross-sectional descriptive study.

Medication adherence in patients with severe asthma prescribed oral corticosteroids in the U-BIOPRED cohort (2021)
Journal Article
Ahmed, H., Auffray, C., Bakke, P., Bush, A., Baribaud, F., Bates, S., …Study Group, U. (2021). Medication adherence in patients with severe asthma prescribed oral corticosteroids in the U-BIOPRED cohort. Chest, 160(1), 53-64. https://doi.org/10.1016/j.chest.2021.02.023

Background: Although estimates of suboptimal adherence to oral corticosteroids in asthma range from 30% to 50%, no ideal method for measurement exists; the impact of poor adherence in severe asthma is likely to be particularly high. Research Question... Read More about Medication adherence in patients with severe asthma prescribed oral corticosteroids in the U-BIOPRED cohort.

Policing mental illness: Police use of section 136 – Perspectives from police and mental-health nurses (2021)
Journal Article
Wondemaghen, M. (2021). Policing mental illness: Police use of section 136 – Perspectives from police and mental-health nurses. Medicine, Science and the Law, 61(4), 266-274. https://doi.org/10.1177/0025802421993363

Ideological shifts in mental health-care policy such as deinstitutionalisation have meant police have had to make decisions about the care of persons with a mental-health crisis. This study examines how police in five English counties respond to cris... Read More about Policing mental illness: Police use of section 136 – Perspectives from police and mental-health nurses.

From light touch to top management control: HSBC’s integration of its first two acquired subsidiaries 1960-1980 (2021)
Journal Article
Lu, Q., Toms, S., & Wei, Y. (2023). From light touch to top management control: HSBC’s integration of its first two acquired subsidiaries 1960-1980. Business history, 65(4), 656-678. https://doi.org/10.1080/00076791.2021.1883000

This research contributes to British multinational banking history, post-acquisition integration and legitimacy research, by exploring HSBC’s top management control integration with its first two acquired British banks, during the period 1960–1980, f... Read More about From light touch to top management control: HSBC’s integration of its first two acquired subsidiaries 1960-1980.

Palliative medicine in the intensive care unit: needs, delivery, quality (2021)
Journal Article
Hill, S., Dawood, A., Boland, E., Leahy, H. E., & Murtagh, F. (in press). Palliative medicine in the intensive care unit: needs, delivery, quality. BMJ supportive & palliative care, Article 2795. https://doi.org/10.1136/bmjspcare-2020-002795

Background: 15%-20% of critical care patients die during their hospital admission. This service evaluation assesses quality of palliative care in intensive care units (ICUs) compared with national standards. Methods: Retrospective review of records f... Read More about Palliative medicine in the intensive care unit: needs, delivery, quality.

Human ex vivo wound model and whole-mount staining approach to accurately evaluate skin repair (2021)
Journal Article
Wilkinson, H. N., Kidd, A. S., Roberts, E. R., & Hardman, M. J. (2021). Human ex vivo wound model and whole-mount staining approach to accurately evaluate skin repair. Journal of visualized experiments : JoVE, 168, Article e62326. https://doi.org/10.3791/62326

© 2021 JoVE Creative Commons. Chronic non-healing wounds, which primarily affect the elderly and diabetic, are a significant area of clinical unmet need. Unfortunately, current chronic wound treatments are inadequate, while available pre-clinical mod... Read More about Human ex vivo wound model and whole-mount staining approach to accurately evaluate skin repair.

Evolutionary biomechanics: hard tissues and soft evidence? (2021)
Journal Article
Broyde, S., Dempsey, M., Wang, L., Cox, P. G., Fagan, M., & Bates, K. T. (2021). Evolutionary biomechanics: hard tissues and soft evidence?. Proceedings of the Royal Society B: Biological Sciences, 288(1945), Article 20202809. https://doi.org/10.1098/rspb.2020.2809

Biomechanical modelling is a powerful tool for quantifying the evolution of functional performance in extinct animals to understand key anatomical innovations and selective pressures driving major evolutionary radiations. However, the fossil record i... Read More about Evolutionary biomechanics: hard tissues and soft evidence?.

An international e-Delphi study to identify core competencies for Italian cardiac nurses (2021)
Journal Article
Bagnasco, A., Barisone, M., Aleo, G., Watson, R., Catania, G., Zanini, M., …Sasso, L. (2021). An international e-Delphi study to identify core competencies for Italian cardiac nurses. European journal of cardiovascular nursing : journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology, 20(7), 684-691. https://doi.org/10.1093/eurjcn/zvab003

Aims The management of cardiovascular patients requires increasingly competent nursing professionals. In Italy, there are no specific postgraduate courses focused on specialist cardiac skills development for nurses. To develop such courses, content i... Read More about An international e-Delphi study to identify core competencies for Italian cardiac nurses.

How physicians in South India recognize, assess, and manage people with chronic breathlessness syndrome: A thematic analysis (2021)
Journal Article
Barnes-Harris, M., Daniel, S., Venkateswaran, C., Hutchinson, A., & Johnson, M. (2021). How physicians in South India recognize, assess, and manage people with chronic breathlessness syndrome: A thematic analysis. Indian Journal of Palliative Care, 27(1), 54-61. https://doi.org/10.4103/IJPC.IJPC_139_20

Objectives: Chronic breathlessness syndrome has been defined to help clinicians actively seek, and patients legitimately present with, persistent breathlessness, and to drive services and research. However, views from low- to middle-income countries... Read More about How physicians in South India recognize, assess, and manage people with chronic breathlessness syndrome: A thematic analysis.

Comparing functional decline and distress from symptoms in people with thoracic life-limiting illnesses: Lung cancers and non-malignant end-stage respiratory diseases (2021)
Journal Article
Barnes-Harris, M., Allingham, S., Morgan, D., Ferreira, D., Johnson, M. J., Eagar, K., & Currow, D. (2021). Comparing functional decline and distress from symptoms in people with thoracic life-limiting illnesses: Lung cancers and non-malignant end-stage respiratory diseases. Thorax, 76(10), 989-995. https://doi.org/10.1136/thoraxjnl-2020-216039

© Author(s) (or their employer(s)) 2021. No commercial re-use. See rights and permissions. Published by BMJ. Background: Malignant and non-malignant respiratory diseases account for >4.6 million deaths annually worldwide. Despite similar symptom burd... Read More about Comparing functional decline and distress from symptoms in people with thoracic life-limiting illnesses: Lung cancers and non-malignant end-stage respiratory diseases.

A circular economy approach for industrial scale biodiesel production from palm oil mill effluent using microwave heating: Design, simulation, techno-economic analysis and location comparison (2021)
Journal Article
Waudby, H., & Zein, S. H. (2021). A circular economy approach for industrial scale biodiesel production from palm oil mill effluent using microwave heating: Design, simulation, techno-economic analysis and location comparison. Process Safety and Environmental Protection, 148, 1006-1018. https://doi.org/10.1016/j.psep.2021.02.011

This paper examines a green approach to produce industrial-scale biodiesel from a palm oil mill effluent (POME) using Microwave Heating. Kinetic data were determined for this reaction and implemented into the Aspen HYSYS simulation software to produc... Read More about A circular economy approach for industrial scale biodiesel production from palm oil mill effluent using microwave heating: Design, simulation, techno-economic analysis and location comparison.

“It’s one of the few things that … pulls us together when the outside world is really tough.” Exploring the outcomes and challenges of a charity-led community garden in a disadvantaged English city (2021)
Journal Article
Ramsden, S. (in press). “It’s one of the few things that … pulls us together when the outside world is really tough.” Exploring the outcomes and challenges of a charity-led community garden in a disadvantaged English city. Local environment, 1-14. https://doi.org/10.1080/13549839.2021.1886067

This article explores a charity-led community gardening project working in a disadvantaged community in northern England and provides a detailed analysis of the outcomes for vulnerable people. This article contributes to the research on community gar... Read More about “It’s one of the few things that … pulls us together when the outside world is really tough.” Exploring the outcomes and challenges of a charity-led community garden in a disadvantaged English city.

The language of behaviour changes in dementia: A mixed methods survey exploring the perspectives of people with dementia (2021)
Journal Article
Wolverson, E., Moniz-Cook, E., Dunn, R., Gove, D., & Diaz-Ponce, A. (2021). The language of behaviour changes in dementia: A mixed methods survey exploring the perspectives of people with dementia. Journal of advanced nursing, 77(4), 1992-2001. https://doi.org/10.1111/jan.14787

Aims: The aim of this study was to explore the opinions of people with dementia, about the language used to describe changes in behaviour associated with dementia. Design: This study adopted a human rights approach in a mixed methods convergent paral... Read More about The language of behaviour changes in dementia: A mixed methods survey exploring the perspectives of people with dementia.

Barriers and enablers of implementation of alcohol guidelines with pregnant women: a cross-sectional survey among UK midwives (2021)
Journal Article
Smith, L. A., Dyson, J., Watson, J., & Schölin, L. (2021). Barriers and enablers of implementation of alcohol guidelines with pregnant women: a cross-sectional survey among UK midwives. BMC Pregnancy and Childbirth, 21(1), Article 134. https://doi.org/10.1186/s12884-021-03583-1

© 2021, The Author(s). Background: In 2016, the UK Chief Medical Officers revised their guidance on alcohol and advised women to abstain from alcohol if pregnant or planning pregnancy. Midwives have a key role in advising women about alcohol during p... Read More about Barriers and enablers of implementation of alcohol guidelines with pregnant women: a cross-sectional survey among UK midwives.

The Chamber of Banality: Hell on Earth (2021)
Journal Article
Arya, R. (2021). The Chamber of Banality: Hell on Earth. Performance Research, 26(1-2), 78--87. https://doi.org/10.1080/13528165.2021.1959237

In Sartre{\textquoteright}s play Huis Clos, hell is conceptualized as a psychological state of mind and interdependence rather than a physical place and is manifested through the conversational exchanges between the three characters, who seek to evad... Read More about The Chamber of Banality: Hell on Earth.

NIR-quantum dots in biomedical imaging and their future (2021)
Journal Article
Gil, H. M., Price, T. W., Chelani, K., Bouillard, J. S. G., Calaminus, S. D., & Stasiuk, G. J. (2021). NIR-quantum dots in biomedical imaging and their future. iScience, 24(3), Article 102189. https://doi.org/10.1016/j.isci.2021.102189

Fluorescence imaging has gathered interest over the recent years for its real-time response and high sensitivity. Developing probes for this modality has proven to be a challenge. Quantum dots (QDs) are colloidal nanoparticles that possess unique opt... Read More about NIR-quantum dots in biomedical imaging and their future.

India Led Growth in South Asia: Empirical Analyses (2021)
Journal Article
Bhattarai, K. (2021). India Led Growth in South Asia: Empirical Analyses. Journal of Development Economics and Finance, 1(2), 401-415

Strategic lessons are drown based on Ramsey model of growth for the South Asia region and empirical panel data analysis on the determinates of growth in it. Given its size of population this region should push for growth and increase its share of glo... Read More about India Led Growth in South Asia: Empirical Analyses.