All Outputs (1363)

On the high-pressure phase stability and elastic properties of β-titanium alloys (2017)
Journal Article
Smith, D., Joris, O. P. J., Sankaran, A., Weekes, H. E., Bull, D. J., Dye, D., Errandonea, D., Smith, D., Joris, O. P. J., Sankaran, A., Weekes, H. E., Bull, D. J., Prior, T. J., Dye, D., Errandonea, D., & Proctor, J. E. (2017). On the high-pressure phase stability and elastic properties of β-titanium alloys. Journal of Physics: Condensed Matter, 29(15), 155401. https://doi.org/10.1088/1361-648x/aa60b6

We have studied the compressibility and stability of different β-titanium alloys at high pressure, including binary Ti-Mo, Ti-24Nb-4Zr-8Sn (Ti2448) and Ti-36Nb-2Ta-0.3O (gum metal). We observed stability of the β phase in these alloys to 40 GPa, well... Read More about On the high-pressure phase stability and elastic properties of β-titanium alloys.

Maintenance of head and neck tumor on-chip: gateway to personalized treatment? (2017)
Journal Article
Bower, R., Green, V. L., Kuvshinova, E., Kuvshinov, D., Karsai, L., Crank, S. T., Stafford, N. D., & Greenman, J. (2017). Maintenance of head and neck tumor on-chip: gateway to personalized treatment?. Future Science OA, 3(2), FSO174. https://doi.org/10.4155/fsoa-2016-0089

Aim: Head and neck squamous cell carcinomas (HNSCC) are solid tumors with low overall survival (40–60%). In a move toward personalized medicine, maintenance of tumor biopsies in microfluidic tissue culture devices is being developed. Methodology/ res... Read More about Maintenance of head and neck tumor on-chip: gateway to personalized treatment?.

The necessity for assessment and management of speech, language and communication needs to take account of cultural and multilingual diversity (2017)
Journal Article
Glazzard, J. (2017). The necessity for assessment and management of speech, language and communication needs to take account of cultural and multilingual diversity. International Journal of Learning, Teaching and Educational Research, 16(2), 11-21

This paper argues for the need for a culturally responsive approach to the identification, assessment and intervention processes for multilingual children with speech, language and communication impairment. It highlights the potential for misdiagnosi... Read More about The necessity for assessment and management of speech, language and communication needs to take account of cultural and multilingual diversity.

The cumulative effects assessment of a coastal ecological restoration project in China: An integrated perspective (2017)
Journal Article
Ma, D., Zhang, L., Fang, Q., Jiang, Y., & Elliott, M. (2017). The cumulative effects assessment of a coastal ecological restoration project in China: An integrated perspective. Marine pollution bulletin, 118(1-2), 254-260. https://doi.org/10.1016/j.marpolbul.2017.02.043

© 2017 Elsevier Ltd Large scale coastal land-claim and sea-enclosing (CLASE) activities have caused habitat destruction, biodiversity losses and water deterioration, thus the local governments in China have recently undertaken seabed dredging and dyk... Read More about The cumulative effects assessment of a coastal ecological restoration project in China: An integrated perspective.

Extracorporeal shockwave therapy for the treatment of lower limb intermittent claudication: Study protocol for a randomised controlled trial (the SHOCKWAVE 1 trial) (2017)
Journal Article
Harwood, A. E., Smith, G. E., Totty, J. P., Carradice, D., Chetter, I. C., Harwood, A., Totty, J., Cayton, T., & Smith, G. (2017). Extracorporeal shockwave therapy for the treatment of lower limb intermittent claudication: Study protocol for a randomised controlled trial (the SHOCKWAVE 1 trial). Trials, 18(1), https://doi.org/10.1186/s13063-017-1844-4

© 2017 The Author(s). Background: Peripheral arterial disease (PAD) has a population prevalence of 4.6% with intermittent claudication (IC) presenting as one of the earliest and most common symptoms. PAD has detrimental effects on patients' walking a... Read More about Extracorporeal shockwave therapy for the treatment of lower limb intermittent claudication: Study protocol for a randomised controlled trial (the SHOCKWAVE 1 trial).

The use of educational game design and play in higher education to influence sustainable behaviour (2017)
Journal Article
Mercer, T. G., Kythreotis, A. P., Robinson, Z. P., Stolte, T., George, S. M., & Haywood, S. K. (2017). The use of educational game design and play in higher education to influence sustainable behaviour. International Journal of Sustainability in Higher Education, 18(3), 359-384. https://doi.org/10.1108/IJSHE-03-2015-0064

Purpose: The purpose of this paper is to discuss a novel life cycle approach to education for sustainable development (ESD) where the students become “design thinkers”. Design/methodology/approach: A case study on the creation, development and utilis... Read More about The use of educational game design and play in higher education to influence sustainable behaviour.

A systematic review examining reducing unplanned hospital admissions in adults with cancer (2017)
Preprint / Working Paper
Walabyeki, J., Macleod, U., Johnson, M., Dyson, J., Oliver, S., Allgar, V., Oviasu, O., Chen, H., Smith, S., & Hammond, T. A systematic review examining reducing unplanned hospital admissions in adults with cancer

Review question:
1. What interventions have been tested and have successfully reduced unplanned hospital admissions in adults with cancer?

2. What are the factors associated with unplanned hospital admissions in adults with cancer?

Enabling the flow of compassionate care: a grounded theory study (2017)
Journal Article
Tierney, S., Seers, K., Tutton, E., & Reeve, J. (2017). Enabling the flow of compassionate care: a grounded theory study. BMC health services research, 17(1), Article 174. https://doi.org/10.1186/s12913-017-2120-8

Background: Compassion has become a topic of increasing interest within healthcare over recent years. Yet despite its raised profile, little research has investigated how compassionate care is enacted and what it means to healthcare professionals (HC... Read More about Enabling the flow of compassionate care: a grounded theory study.

Inhaled corticosteriod use and the risk of pneumonia and COPD exacerbations in the UPLIFT study (2017)
Journal Article
Morjaria, J. B., Morice, A. H., Morice, A., Rigby, A., & Morjaria, J. (2017). Inhaled corticosteriod use and the risk of pneumonia and COPD exacerbations in the UPLIFT study. Lung, 195(3), 281-288. https://doi.org/10.1007/s00408-017-9990-8

Rationale Unlike many other COPD studies, the 4-year UPLIFT trial permitted inhaled corticosteroid (ICS) use during run-in and treatment phases. This provided the opportunity to prospectively observe the continuing effects of ICS on respiratory event... Read More about Inhaled corticosteriod use and the risk of pneumonia and COPD exacerbations in the UPLIFT study.

Maternal metabolic stress may affect oviduct gatekeeper function (2017)
Journal Article
Jordaens, L., van Hoeck, V., Maillo, V., Gutiérrez-Adán, A., Marei, W., Vlaeminck, B., Thys, S., Sturmey, R., Bols, P., & Leroy, J. L. M. R. (2017). Maternal metabolic stress may affect oviduct gatekeeper function. Reproduction, 153(6), 759-773. https://doi.org/10.1530/rep-16-0569

We hypothesized that elevated non-esterified fatty acids (NEFA) modify in vitro bovine oviduct epithelial cell (BOEC) metabolism and barrier function. Hereto, BOECs were studied in a polarized system with 24h-treatments at day 9: 1) CONTROL (0µM NEFA... Read More about Maternal metabolic stress may affect oviduct gatekeeper function.

Dialkylcarbamoyl chloride (DACC)-coated dressings in the management and prevention of wound infection: A systematic review (2017)
Journal Article
Totty, J., Bua, N., Smith, G., Harwood, A., Carradice, D., Wallace, T., & Chetter, I. (2017). Dialkylcarbamoyl chloride (DACC)-coated dressings in the management and prevention of wound infection: A systematic review. Journal of Wound Care, 26(3), 107-114. https://doi.org/10.12968/jowc.2017.26.3.107

Objective: Dialkylcarbomoyl chloride (DACC)-coated dressings (Leukomed Sorbact and Cutimed Sorbact) irreversibly bind bacteria at the wound surface that are then removed when the dressing is changed. They are a recent addition to the wound care profe... Read More about Dialkylcarbamoyl chloride (DACC)-coated dressings in the management and prevention of wound infection: A systematic review.

Plant-expressed hepatitis B core antigen virus-like particles : characterization and investigation of their stability in simulated and pig gastro-intestinal fluids (2017)
Journal Article
Berardi, A., Lomonossoff, G. P., Evans, D. J., & Barker, S. A. (2017). Plant-expressed hepatitis B core antigen virus-like particles : characterization and investigation of their stability in simulated and pig gastro-intestinal fluids. International Journal of Pharmaceutics, 522(1-2), 147-156. https://doi.org/10.1016/j.ijpharm.2017.03.001

Virus-like particles (VLPs) are potential oral vaccine candidates, as their highly compact structure may allow them to withstand the harsh conditions of the gastro-intestinal (GI) environment. Hepatitis B core antigen (HBcAg) is an immunogenic protei... Read More about Plant-expressed hepatitis B core antigen virus-like particles : characterization and investigation of their stability in simulated and pig gastro-intestinal fluids.

Bovine and human becomings in histories of dairy technologies: robotic milking systems and remaking animal and human subjectivity (2017)
Journal Article
HOLLOWAY, L., & BEAR, C. (2017). Bovine and human becomings in histories of dairy technologies: robotic milking systems and remaking animal and human subjectivity. BJHS Themes, 2, 215-234. https://doi.org/10.1017/bjt.2017.2

This paper positions the recent emergence of robotic or automatic milking systems (AMS) in relation to discourses surrounding the longer history of milking technologies in the UK and elsewhere. The mechanisation of milking has been associated with se... Read More about Bovine and human becomings in histories of dairy technologies: robotic milking systems and remaking animal and human subjectivity.

Novel non-invasive algorithm to identify the origins of re-entry and ectopic foci in the atria from 64-lead ECGs. A computational study (2017)
Journal Article
Alday, E. A. P., Colman, M. A., Langley, P., & Zhang, H. (2017). Novel non-invasive algorithm to identify the origins of re-entry and ectopic foci in the atria from 64-lead ECGs. A computational study. PLoS Computational Biology, 13(3), e1005270. https://doi.org/10.1371/journal.pcbi.1005270

Atrial tachy-arrhytmias, such as atrial fibrillation (AF), are characterised by irregular electrical activity in the atria, generally associated with erratic excitation underlain by re-entrant scroll waves, fibrillatory conduction of multiple wavelet... Read More about Novel non-invasive algorithm to identify the origins of re-entry and ectopic foci in the atria from 64-lead ECGs. A computational study.

Patterns and persistence of behavioural and psychological symptoms in those with cognitive impairment: the importance of apathy (2017)
Journal Article
van der Linde, R. M., Matthews, F. E., Dening, T., & Brayne, C. (2017). Patterns and persistence of behavioural and psychological symptoms in those with cognitive impairment: the importance of apathy. International journal of geriatric psychiatry, 32(3), 306-315. https://doi.org/10.1002/gps.4464

Objective: To study the stability and emergence of a range of behavioural and psychological symptoms (BPS), their association with mortality and the effect of covariates on these transitions in a population-based study of cognitively impaired older p... Read More about Patterns and persistence of behavioural and psychological symptoms in those with cognitive impairment: the importance of apathy.

Association of delirium with cognitive decline in late life: A neuropathologic study of 3 population-based cohort studies (2017)
Journal Article
Davis, D. H., Muniz-Terrera, G., Keage, H. A., Stephan, B. C., Fleming, J., Ince, P. G., …Oinas, M. (2017). Association of delirium with cognitive decline in late life: A neuropathologic study of 3 population-based cohort studies. JAMA Psychiatry, 74(3), 244-251. https://doi.org/10.1001/jamapsychiatry.2016.3423

Importance: Delirium is associated with accelerated cognitive decline. The pathologic substrates of this association are not yet known, that is, whether they are the same as those associated with dementia, are independent, or are interrelated. Object... Read More about Association of delirium with cognitive decline in late life: A neuropathologic study of 3 population-based cohort studies.

Potentially modifiable lifestyle factors, cognitive reserve, and cognitive function in later life: A cross-sectional study (2017)
Journal Article
Clare, L., Wu, Y. T., Teale, J. C., MacLeod, C., Matthews, F., Brayne, C., & Woods, B. (2017). Potentially modifiable lifestyle factors, cognitive reserve, and cognitive function in later life: A cross-sectional study. PLoS Medicine, 14(3), https://doi.org/10.1371/journal.pmed.1002259

Background: Potentially modifiable lifestyle factors may influence cognitive health in later life and offer potential to reduce the risk of cognitive decline and dementia. The concept of cognitive reserve has been proposed as a mechanism to explain i... Read More about Potentially modifiable lifestyle factors, cognitive reserve, and cognitive function in later life: A cross-sectional study.

Dementia incidence trend over 1992-2014 in the Netherlands: Analysis of primary care data (2017)
Journal Article
van Bussel, E. F., Richard, E., Arts, D. L., Nooyens, A. C., Coloma, P. M., de Waal, M. W., …Moll van Charante, E. P. (2017). Dementia incidence trend over 1992-2014 in the Netherlands: Analysis of primary care data. PLoS Medicine, 14(3), https://doi.org/10.1371/journal.pmed.1002235

Background: Recent reports have suggested declining age-specific incidence rates of dementia in high-income countries over time. Improved education and cardiovascular health in early age have been suggested to be bringing about this effect. The aim o... Read More about Dementia incidence trend over 1992-2014 in the Netherlands: Analysis of primary care data.

Age-related cognitive decline and associations with sex, education and apolipoprotein E genotype across ethnocultural groups and geographic regions: a collaborative cohort study (2017)
Journal Article
Lipnicki, D. M., Crawford, J. D., Dutta, R., Thalamuthu, A., Kochan, N. A., Andrews, G., …Sachdev, P. S. (2017). Age-related cognitive decline and associations with sex, education and apolipoprotein E genotype across ethnocultural groups and geographic regions: a collaborative cohort study. PLoS Medicine, 14(3), https://doi.org/10.1371/journal.pmed.1002261

Background: The prevalence of dementia varies around the world, potentially contributed to by international differences in rates of age-related cognitive decline. Our primary goal was to investigate how rates of age-related decline in cognitive test... Read More about Age-related cognitive decline and associations with sex, education and apolipoprotein E genotype across ethnocultural groups and geographic regions: a collaborative cohort study.

Assessing reading development through systematic synthetic phonics (2017)
Journal Article
Glazzard, J. (2017). Assessing reading development through systematic synthetic phonics. English in Education, 51(1), 44-57. https://doi.org/10.1111/eie.12125

This narrative literature review evaluates the effectiveness of synthetic phonics in comparison with analytic phonics. It presents the key research findings and offers a critical appraisal of this research. Primary schools have developed a variety of... Read More about Assessing reading development through systematic synthetic phonics.