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Pharmacodynamics, pharmacokinetics and CYP3A4 interaction potential of the selective P2X3 receptor antagonist filapixant: A randomized multiple ascending-dose study in healthy young men (2024)
Journal Article
Friedrich, C., Singh, D., Francke, K., Klein, S., Hetzel, T., Zolk, O., Gashaw, I., Scheerans, C., & Morice, A. (2024). Pharmacodynamics, pharmacokinetics and CYP3A4 interaction potential of the selective P2X3 receptor antagonist filapixant: A randomized multiple ascending-dose study in healthy young men. British Journal of Clinical Pharmacology, https://doi.org/10.1111/bcp.16091

Aims: We report on investigations exploring the P2X3-receptor antagonist filapixant's effect on taste perception and cough-reflex sensitivity and describe its pharmacokinetics, including its CYP3A4-interaction potential. Methods: In a randomized, pla... Read More about Pharmacodynamics, pharmacokinetics and CYP3A4 interaction potential of the selective P2X3 receptor antagonist filapixant: A randomized multiple ascending-dose study in healthy young men.

Environmental behaviour of iron and steel slags in coastal settings (2024)
Journal Article
Riley, A. L., Cameron, J., Burke, I. T., Onnis, P., Macdonald, J. M., Gandy, C. J., Crane, R. A., Byrne, P., Comber, S., Jarvis, A. P., Hudson-Edwards, K. A., & Mayes, W. M. (2024). Environmental behaviour of iron and steel slags in coastal settings. Environmental science and pollution research, https://doi.org/10.1007/s11356-024-33897-4

Iron and steel slags have a long history of both disposal and beneficial use in the coastal zone. Despite the large volumes of slag deposited, comprehensive assessments of potential risks associated with metal(loid) leaching from iron and steel by-pr... Read More about Environmental behaviour of iron and steel slags in coastal settings.

Morphometric fingerprints and downslope evolution in bathymetric surveys: insights into morphodynamics of the Congo canyon-channel (2024)
Journal Article
Hasenhündl, M., Talling, P. J., Pope, E. L., Baker, M. L., Heijnen, M. S., Ruffell, S. C., da Silva Jacinto, R., Jacinto, S., Gaillot, A., Hage, S., Simmons, S. M., Heerema, C. J., McGhee, C., Clare, M. A., & Cartigny, M. J. (2024). Morphometric fingerprints and downslope evolution in bathymetric surveys: insights into morphodynamics of the Congo canyon-channel. Frontiers in Earth Science, 12, Article 1381019. https://doi.org/10.3389/feart.2024.1381019

Submarine canyons and channels are globally important pathways for sediment, organic carbon, nutrients and pollutants to the deep sea, and they form the largest sediment accumulations on Earth. However, studying these remote submarine systems compreh... Read More about Morphometric fingerprints and downslope evolution in bathymetric surveys: insights into morphodynamics of the Congo canyon-channel.

The symptom to assessment pathway for suspected chronic limb-threatening ischaemia (CLTI) affects quality of care: a process mapping exercise (2024)
Journal Article
Atkins, E., Kellar, I., Birmpili, P., Waton, S., Li, Q., Johal, A. S., …Cromwell, D. A. (2024). The symptom to assessment pathway for suspected chronic limb-threatening ischaemia (CLTI) affects quality of care: a process mapping exercise. BMJ Open Quality, 13(1), Article e002605. https://doi.org/10.1136/bmjoq-2023-002605

Background Delays in the pathway from first symptom to treatment of chronic limb-threatening ischaemia (CLTI) are associated with worse mortality and limb loss outcomes. This study examined the processes used by vascular services to provide urgent ca... Read More about The symptom to assessment pathway for suspected chronic limb-threatening ischaemia (CLTI) affects quality of care: a process mapping exercise.

Advancements in the management of obesity: a review of current evidence and emerging therapies (2024)
Journal Article
Abdalla Ahmed, M. A., Ssemmondo, E., Mark-Wagstaff, C., & Sathyapalan, T. (2024). Advancements in the management of obesity: a review of current evidence and emerging therapies. Expert Review of Endocrinology and Metabolism, 19(3), 257-268. https://doi.org/10.1080/17446651.2024.2347258

Introduction: Obesity is the modern world’s current epidemic, with substantial health and economic impact. This study aimed to provide a narrative overview of the past, currently available, and future treatment options that offer therapeutic and prev... Read More about Advancements in the management of obesity: a review of current evidence and emerging therapies.

The role of cardiopulmonary exercise testing for identifying possible silent myocardial ischaemia in people with coronary heart disease (2024)
Thesis
Nickolay, T. (2024). The role of cardiopulmonary exercise testing for identifying possible silent myocardial ischaemia in people with coronary heart disease. (Thesis). University of Hull and University of York. https://hull-repository.worktribe.com/output/4659878

This thesis investigates the utility of cardiopulmonary exercise testing (CPET) in assessing and managing patients with coronary artery disease (CAD), particularly focusing on the significance of oxygen pulse (O2Pulse) inflections as a marker for myo... Read More about The role of cardiopulmonary exercise testing for identifying possible silent myocardial ischaemia in people with coronary heart disease.

Views of patients with progressive illness and carers about the role of digital advance care planning systems to record and share information: a qualitative study (2024)
Journal Article
Birtwistle, J., Allsop, M. J., Bradshaw, A., Millares Martin, P., Sleeman, K. E., Twiddy, M., & Evans, C. J. (2024). Views of patients with progressive illness and carers about the role of digital advance care planning systems to record and share information: a qualitative study. Palliative medicine, 38(7), 711-724. https://doi.org/10.1177/02692163241255511

Background: Digital approaches are being explored internationally to support the elicitation, documentation and sharing of advance care planning information. However, the views and experiences of patients and carers are little understood, impeding th... Read More about Views of patients with progressive illness and carers about the role of digital advance care planning systems to record and share information: a qualitative study.

Ex situ experimentation to determine if introduced artificial habitat can provide alternative refuge to hazardous anthropogenic structures (2024)
Journal Article
Norman, J., Clark, D., Henshaw, A., Wright, R. M., Cattaneo, M. E. G. V., & Bolland, J. D. (2024). Ex situ experimentation to determine if introduced artificial habitat can provide alternative refuge to hazardous anthropogenic structures. Restoration Ecology, Article e14157. https://doi.org/10.1111/rec.14157

Highly degraded lowland river ecosystems are of global concern to restoration practitioners. Hazardous anthropogenic structures, such as those used for water level management (i.e. pumping stations), present a mortality risk to fish and associated ch... Read More about Ex situ experimentation to determine if introduced artificial habitat can provide alternative refuge to hazardous anthropogenic structures.

Isolating the effects of visual imagery on prospective memory (2024)
Journal Article
Abel, J. W., Anderson, R. J., Dean, G. M., & Dewhurst, S. A. (2024). Isolating the effects of visual imagery on prospective memory. Memory, https://doi.org/10.1080/09658211.2024.2335302

Two experiments investigated the role of visual imagery in prospective memory (PM). In experiment 1, 140 participants completed a general knowledge quiz which included a PM task of writing a letter “X” next to any questions that referred to space. Pa... Read More about Isolating the effects of visual imagery on prospective memory.

The Influence of Joe Wicks on Physical Activity During the COVID-19 Pandemic: Thematic, Location, and Social Network Analysis of X Data (2024)
Journal Article
Ahmed, W., Aiyenitaju, O., Chadwick, S., Hardey, M., & Fenton, A. (2024). The Influence of Joe Wicks on Physical Activity During the COVID-19 Pandemic: Thematic, Location, and Social Network Analysis of X Data. Journal of medical Internet research, 26, Article e49921. https://doi.org/10.2196/49921

Background: Social media (SM) was essential in promoting physical activity during the COVID-19 pandemic, especially among people confined to their homes. Joe Wicks, a fitness coach, became particularly popular on SM during this time, posting daily wo... Read More about The Influence of Joe Wicks on Physical Activity During the COVID-19 Pandemic: Thematic, Location, and Social Network Analysis of X Data.

Emigration of post-spawned twaite shad Alosa fallax, an anadromous and iteroparous fish, in a highly fragmented river (2024)
Journal Article
Yeldham, M. I., Britton, J. R., Crundwell, C., Davies, P., Dodd, J. R., Nunn, A. D., …Bolland, J. D. (2024). Emigration of post-spawned twaite shad Alosa fallax, an anadromous and iteroparous fish, in a highly fragmented river. Journal of fish biology, https://doi.org/10.1111/jfb.15713

Anthropogenic barriers are widely known to negatively impact the spawning migrations of anadromous fishes, by delaying or preventing passage upstream. Although the impacts of barriers on emigrating post-spawned adults are less well studied, they coul... Read More about Emigration of post-spawned twaite shad Alosa fallax, an anadromous and iteroparous fish, in a highly fragmented river.

Human capital in the financial sector and corporate innovation: Evidence from China (2024)
Journal Article
Liu, G., He, F., Zhang, C., Akbar, S., & Li, Y. (2024). Human capital in the financial sector and corporate innovation: Evidence from China. The British accounting review, Article 101370. https://doi.org/10.1016/j.bar.2024.101370

This paper investigates how human capital in the financial sector affects corporate innovation. Based on China's National Economic Census in 2008, we construct a measure of the financial sector's human capital across prefecture-level cities and then... Read More about Human capital in the financial sector and corporate innovation: Evidence from China.

Telephone advice lines for adults with advanced illness and their family carers: a qualitative analysis and novel practical framework (2024)
Journal Article
Pask, S., Omoruyi, A., Mohamed, A., Chambers, R. L., McFarlane, P. G., Johansson, T., …Murtagh, F. E. (2024). Telephone advice lines for adults with advanced illness and their family carers: a qualitative analysis and novel practical framework. Palliative medicine, https://doi.org/10.1177/02692163241242329

Background: Telephone advice lines have been recommended internationally to support around-the-clock care for people living at home with advanced illness. While they undoubtedly support care, there is little evidence about what elements are needed fo... Read More about Telephone advice lines for adults with advanced illness and their family carers: a qualitative analysis and novel practical framework.

Gravity current escape from a topographic depression (2024)
Journal Article
Skevington, E. W., & Hogg, A. J. (2024). Gravity current escape from a topographic depression. Physical Review Fluids, 9(1), Article 014802. https://doi.org/10.1103/PhysRevFluids.9.014802

An inertial gravity current released within a topographic depression may climb up the incline from a lower to an upper plateau if it is sufficiently energetic and then continue to flow unsteadily away from the step while simultaneously draining back... Read More about Gravity current escape from a topographic depression.

Association study of human leukocyte antigen variants and idiopathic pulmonary fibrosis (2024)
Journal Article
Guillen-Guio, B., Paynton, M. L., Allen, R. J., Chin, D. P., Donoghue, L. J., Stockwell, A., …Hollox, E. J. (2024). Association study of human leukocyte antigen variants and idiopathic pulmonary fibrosis. ERJ Open Research, 10(1), https://doi.org/10.1183/23120541.00553-2023

Introduction Idiopathic pulmonary fibrosis (IPF) is a chronic interstitial pneumonia marked by progressive lung fibrosis and a poor prognosis. Recent studies have highlighted the potential role of infection in the pathogenesis of IPF, and a prior ass... Read More about Association study of human leukocyte antigen variants and idiopathic pulmonary fibrosis.

Erratum: Correction: Supported: Supporting, enabling, and sustaining homecare workers to deliver end-of-life care: A qualitative study protocol (PloS one (2023) 18 12 (e0291525)) (2024)
Journal Article
Bayley, Z., Bothma, J., Bravington, A., Forward, C., Hussain, J., Manthorpe, J., Pearson, M., Roberts, H., Taylor, P., Walker, L., White, C., Wray, J., & Johnson, M. J. (2024). Erratum: Correction: Supported: Supporting, enabling, and sustaining homecare workers to deliver end-of-life care: A qualitative study protocol (PloS one (2023) 18 12 (e0291525)). PLoS ONE, 19(2), Article e0298925. https://doi.org/10.1371/journal.pone.0298925

[This corrects the article DOI: 10.1371/journal.pone.0291525.].

Pickering emulsion droplets and solid microspheres acting synergistically for continuous-flow cascade reactions (2024)
Journal Article
Zhang, M., Ettelaie, R., Li, T., Yang, J., Dong, L., Xue, N., …Yang, H. (2024). Pickering emulsion droplets and solid microspheres acting synergistically for continuous-flow cascade reactions. Nature Catalysis, https://doi.org/10.1038/s41929-024-01110-x

Integration of multiple incompatible catalysts in one continuous-flow reaction system is of paramount significance for green synthetic chemistry. Here we develop a continuous-flow cascade catalytic system by co-packing micrometre-sized Pickering emul... Read More about Pickering emulsion droplets and solid microspheres acting synergistically for continuous-flow cascade reactions.

Extracorporeal Shockwave for Intermittent Claudication and Quality of Life: A Randomized Clinical Trial (2024)
Journal Article
Cai, P., Pymer, S., Raza, A., Ibeggazene, S., Hitchman, L., Chetter, I., & Smith, G. (2024). Extracorporeal Shockwave for Intermittent Claudication and Quality of Life: A Randomized Clinical Trial. JAMA Surgery, https://doi.org/10.1001/jamasurg.2024.0625

Importance: Intermittent lower limb claudication limits function and quality of life. Supervised exercise programs are not readily available, and a noninvasive alternative is needed. Objective: To assess extracorporeal corporeal shockwave therapy in... Read More about Extracorporeal Shockwave for Intermittent Claudication and Quality of Life: A Randomized Clinical Trial.