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The timing of development and subsequent clinical course of heart failure after a myocardial infarction (2008)
Journal Article
Torabi, A., Cleland, J. G., Khan, N. K., Loh, P. H., Clark, A. L., Alamgir, F., …Goode, K. (2008). The timing of development and subsequent clinical course of heart failure after a myocardial infarction. European Heart Journal, 29(7), 859-870. https://doi.org/10.1093/eurheartj/ehn096

Aims: Myocardial infarction (MI) is a common cause of heart failure (HF), which may develop early and persist or resolve, or develop late. The cumulative incidence, persistence, and resolution of HF after MI are poorly described. The aim of this stud... Read More about The timing of development and subsequent clinical course of heart failure after a myocardial infarction.

Brain imaging of acupuncture: comparing superficial with deep needling (2008)
Journal Article
MacPherson, H., Green, G., Nevado, A., Lythgoe, M. F., Lewith, G., Devlin, R., …Asghar, A. U. R. (2008). Brain imaging of acupuncture: comparing superficial with deep needling. Neuroscience letters, 434(1), 144-149. https://doi.org/10.1016/j.neulet.2008.01.058

The difference between superficial and deep needling at acupuncture points has yet to be mapped with functional magnetic resonance imaging (fMRI). Using a 3 T MRI, echo planar imaging data were acquired for 17 right-handed healthy volunteer participa... Read More about Brain imaging of acupuncture: comparing superficial with deep needling.

Fluvastatin reduces oxidative damage in human vascular endothelial cells by upregulating Bcl-2 (2008)
Journal Article
Xu, S. Z., Zhong, W., Watson, N. M., Dickerson, E., Wake, J. D., Lindow, S. W., …Atkin, S. L. (2008). Fluvastatin reduces oxidative damage in human vascular endothelial cells by upregulating Bcl-2. Journal of thrombosis and haemostasis : JTH, 6(4), 692-700. https://doi.org/10.1111/j.1538-7836.2008.02913.x

Background: 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) have been widely used in clinical practise and their efficacy in reducing cardiovascular risk has been well described. Objectives: To investigate the effect of low doses... Read More about Fluvastatin reduces oxidative damage in human vascular endothelial cells by upregulating Bcl-2.

Treating the hotel like a home: the contribution of studying the single location home/workplace (2007)
Journal Article
Seymour, J. (2007). Treating the hotel like a home: the contribution of studying the single location home/workplace. Sociology, 41(6), 1097-1114. https://doi.org/10.1177/0038038507082317

This article contributes to research on the dynamic of space and social life by examining a comparatively uncommon, configuration; that of the single location home/workplace, It draws on an empirical study of family-run hotels, pubs and boarding hous... Read More about Treating the hotel like a home: the contribution of studying the single location home/workplace.

Mean blood glucose compared with HbA1c in the prediction of cardiovascular disease in patients with type 1 diabetes (2007)
Journal Article
Kilpatrick, E. S., Rigby, A. S., & Atkin, S. L. (2008). Mean blood glucose compared with HbA1c in the prediction of cardiovascular disease in patients with type 1 diabetes. Diabetologia, 51(2), 365-371. https://doi.org/10.1007/s00125-007-0883-x

Aims/hypothesisIt is not known whether mean blood glucose (MBG) predicts the risk of macrovascular complications in diabetes any differently from HbA1c. In this study we therefore analysed data from the Diabetes Control and Complications Trial (DCCT)... Read More about Mean blood glucose compared with HbA1c in the prediction of cardiovascular disease in patients with type 1 diabetes.

Shared prescribing? A focus group study with community pharmacists (2007)
Journal Article
Irving, G., Hilton, A., & Campion, P. (2007). Shared prescribing? A focus group study with community pharmacists. Primary Health Care Research and Development, 8(4), 308-314. https://doi.org/10.1017/S1463423607000400

Background: in the Community, randomised over Time) trial was a multi-centre pragmatic trial of pharmaceutical care in the community, which took place in five areas of East and North Yorkshire. of community pharmacists towards the process of ‘pharmac... Read More about Shared prescribing? A focus group study with community pharmacists.

Lesion T2 relaxation times and volumes predict the response of malignant breast lesions to neoadjuvant chemotherapy (2007)
Journal Article
Tan, P. C., Pickles, M. D., Lowry, M., Manton, D. J., & Turnbull, L. W. (2008). Lesion T2 relaxation times and volumes predict the response of malignant breast lesions to neoadjuvant chemotherapy. Magnetic Resonance Imaging, 26(1), 26-34. https://doi.org/10.1016/j.mri.2007.04.002

The aim of this study was to investigate the utility of the water T-2 values of malignant breast lesions in predicting response after the first and second cycles of neoadjuvant chemotherapy (NAC), both alone and in combination with lesion volumes. Th... Read More about Lesion T2 relaxation times and volumes predict the response of malignant breast lesions to neoadjuvant chemotherapy.

Cutaneous hyperpigmentation after endovenous laser therapy: a case report and literature review (2007)
Journal Article
Mekako, A., & Chetter, I. (2007). Cutaneous hyperpigmentation after endovenous laser therapy: a case report and literature review. Annals of vascular surgery, 21(5), 637-639. https://doi.org/10.1016/j.avsg.2007.03.013

Endovenous laser therapy (EVLT) for the treatment of varicose veins has been shown to be effective and relatively safe. Reported complications are few and transient. Whereas it is not uncommon to have cutaneous hyperpigmentation following treatment m... Read More about Cutaneous hyperpigmentation after endovenous laser therapy: a case report and literature review.

Plasma tissue factor is a predictor for restenosis after femoropopliteal angioplasty (2007)
Journal Article
Ray, B., Chetter, I. C., Lee, H. L. D., Ettelaie, C., & McCollum, P. T. (2007). Plasma tissue factor is a predictor for restenosis after femoropopliteal angioplasty. British journal of surgery, 94(9), 1092-1095. https://doi.org/10.1002/bjs.5759

Background:In vitro studies suggest an association between raised levels of tissue factor and restenosis after coronary percutaneous transluminal angioplasty (PTA). This prospective, controlled study examined the association between plasma tissue fac... Read More about Plasma tissue factor is a predictor for restenosis after femoropopliteal angioplasty.

Changes in body composition in patients with left ventricular systolic dysfunction initiated on beta-blocker therapy (2007)
Journal Article
Ingle, L., Rigby, A. S., Carroll, S., Butterly, R., King, R. F., Cooke, C. B., …Clark, A. L. (2007). Changes in body composition in patients with left ventricular systolic dysfunction initiated on beta-blocker therapy. Experimental and Clinical Cardiology, 12(1), 46-47

Background: Increasing body mass index, cholesterol and body fat are associated with a better prognosis in patients with left ventricular systolic dysfunction (LVSD). Beta-blocker usage is associated with changes in body composition and increased bod... Read More about Changes in body composition in patients with left ventricular systolic dysfunction initiated on beta-blocker therapy.

Prognostic value of the 6 min walk test and self-perceived symptom severity in older patients with chronic heart failure (2007)
Journal Article
Ingle, L., Rigby, A. S., Carroll, S., Butterly, R., King, R. F., Cooke, C. B., …Clark, A. L. (2007). Prognostic value of the 6 min walk test and self-perceived symptom severity in older patients with chronic heart failure. European Heart Journal, 28(5), 560-568. https://doi.org/10.1093/eurheartj/ehl527

Background: The 6 min walk test (6-MWT) is a simple and popular test for evaluating functional status in patients with chronic heart failure (CHF). However, the prognostic value of the 6-MWT in a large, representative sample of CHF patients, and in p... Read More about Prognostic value of the 6 min walk test and self-perceived symptom severity in older patients with chronic heart failure.

Anterior anal sphincter repair for fecal incontinence: Good longterm results are possible (2006)
Journal Article
Maslekar, S., Gardiner, A. B., & Duthie, G. S. (2007). Anterior anal sphincter repair for fecal incontinence: Good longterm results are possible. Journal of The American College of Surgeons, 204(1), 40-46. https://doi.org/10.1016/j.jamcollsurg.2006.10.008

Background: Anterior anal sphincter repair (ASR) is standard treatment for fecal incontinence resulting from an obstetrically damaged anal sphincter. Longterm results of repair have generally been shown to be poor. This review of single-unit series a... Read More about Anterior anal sphincter repair for fecal incontinence: Good longterm results are possible.

A nonrandomised controlled trial of endovenous laser therapy and surgery in the treatment of varicose veins (2006)
Journal Article
Mekako, A. I., Hatfield, J., Bryce, J., Lee, D., McCollum, P. T., & Chetter, I. (2006). A nonrandomised controlled trial of endovenous laser therapy and surgery in the treatment of varicose veins. Annals of vascular surgery, 20(4), 451-457. https://doi.org/10.1007/s10016-006-9095-y

Endovenous laser therapy (EVLT) is a minimally invasive treatment for varicose veins. This study compares early quality-of-life (QoL) outcomes following EVLT and surgery. Two nonrandomized groups were studied: an EVLT group with 70 patients, median a... Read More about A nonrandomised controlled trial of endovenous laser therapy and surgery in the treatment of varicose veins.

Combined endovenous laser therapy and ambulatory phlebectomy: refinement of a new technique (2006)
Journal Article
Mekako, A., Hatfield, J., Bryce, J., Lee, D., Heng, M., McCollum, P., & Chetter, I. (2006). Combined endovenous laser therapy and ambulatory phlebectomy: refinement of a new technique. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 32(6), 725-729. https://doi.org/10.1016/j.ejvs.2006.06.002

Objective. Sclerotherapy (IS) or ambulatory phlebectomy (AP) are required as subsequent interventions in majority of cases following endovenous laser therapy (EVLT). We assessed whether AP performed concomitantly with EVLT (EVLTAP), is effective, acc... Read More about Combined endovenous laser therapy and ambulatory phlebectomy: refinement of a new technique.

Clinical determinants of poor six-minute walk test performance in patients with left ventricular systolic dysfunction and no major structural heart disease (2006)
Journal Article
Ingle, L., Rigby, A. S., Nabb, S., Jones, P. K., Clark, A. L., & Cleland, J. G. (2006). Clinical determinants of poor six-minute walk test performance in patients with left ventricular systolic dysfunction and no major structural heart disease. European journal of heart failure, 8(3), 321-325. https://doi.org/10.1016/j.ejheart.2005.08.006

Background: The clinical determinants of six-minute walk test (6-MWT) performance in patients with left ventricular systolic dysfunction (LVSD) have rarely been investigated, and it is not clear whether they differ from patients referred for the asse... Read More about Clinical determinants of poor six-minute walk test performance in patients with left ventricular systolic dysfunction and no major structural heart disease.

Abstracts of the AGA Institute (2006)
Journal Article
Gardiner, A., Maslekar, S., & Duthie, G. (2006). Abstracts of the AGA Institute. Gastroenterology, 130(4), A-1-A-747. https://doi.org/10.1016/s0016-5085%2806%2960008-5

Aims: Artificial neural networks (ANN) are computer programs used to identify complexrelations within data that cannot be detected with conventional linear-statistical analysis.The routine clinical predictions of need for lower gastrointestinal endos... Read More about Abstracts of the AGA Institute.

Non-medical colonoscopy (2006)
Journal Article
Maslekar, S. K., Gardiner, A., Hughes, M., & Duthie, G. S. (2006). Non-medical colonoscopy. Gastrointestinal Endoscopy, 63(5), AB114. https://doi.org/10.1016/j.gie.2006.03.148

Aims: There is increasing demand for colonoscopy especially with introduction of screening programmes. Though colonoscopy is performed by doctors and nurses, there is an acute shortage of trained colonoscopists